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The map label for this gene is trpS [H]

Identifier: 229586829

GI number: 229586829

Start: 727426

End: 728418

Strand: Direct

Name: trpS [H]

Synonym: RAF_ORF0697

Alternate gene names: 229586829

Gene position: 727426-728418 (Clockwise)

Preceding gene: 229586826

Following gene: 229586837

Centisome position: 56.9

GC content: 33.23

Gene sequence:

>993_bases
ATGAAAAAAACTGTTCTTTCCGGTGTGCAAGCAACCGGTTCTTTACATCTCGGTAACTATCTTGGTGCAATTAAAAACTG
GGTTAAAATGCAGGAAGAATATAATTGTTTTTTCTTCTTAGCAGATTTGCATGCTATCACGGTTGATATTAAGCCATCAG
AACTTAACAATTCAATTATGGAGGTGCTTGCTGTTTATTTAGCAGCAGGGCTTAACCCCGACAAAGTAACGATTTTTGCC
CAAAGTATGGTGAAAGAGCATACTGAACTTGCTTGGCTACTAAATTGCGTTACACCGCTTGGATGGTTAAAGCGCATGAC
ACAATTTAAAGATAAAGCAGGTAGCGATCAAGAAAAGGCTTGTCTTGGGTTATTTTCCTATCCGGTACTTATGGCAGCGG
ATATCTTAATATATAAAGCCGATATAGTGCCTGTAGGTGAGGATCAGAAACAGCATTTAGAACTAACAAGAGATATTGCA
GGGGTAATAAATAGAAAATTTAACAAAGAAATTCTAAAAGTTCCTGAGGTGTTAATTAGTGAAACAGGCACAAGAATCAT
GAGCTTACGGGATGGATTAAAGAAAATGAGTAAATCTGATATTTCGGATTTTTCCCGTATCAATTTAAAAGACAATAACG
ATCTTATTCATCAAAAAATAAAAAAAGCCAAAACCGATCATTTAAGTTTTGTTAGCTATGATCAAGAAACAAGACCGGAA
ATTAGTAATTTATTAGATATTTATAGCAGTTTATCCGAAGAAAGCTTGGAAAAAATAATCGGTAATTATCAAAACCAAGG
TTTCGCAAAATTTAAAGAAGATTTGGCAGAAATTATTATTACAAATCTACAACCGATACGTAATAAATATTTAGAATTAA
TGAATGATAAAGAATATTTATTAAAAATACTGCACAAAGGAGCAGAAAAAGCAAGAATTAGAGCTTCTGAAACGGTTAAT
GAAGTGAAAGAACAATTCGGATTTGTAATTTAG

Upstream 100 bases:

>100_bases
AAAATTCTTAAACGCCACAGCATAATTATTAAGATAATTATATTAATTAAAATGGTATTTATAACATAATTTTACAATGA
GTAAAATAAAAAGGTATTAA

Downstream 100 bases:

>100_bases
ATTCATATATTGCAAGATTTCCCTTGAAATATATAAGATTATTTGGTATGAATCTTCTTGGATAGGTGGCCGAGTGGTTT
AAGGCACTAGTCTTGAAAAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDNNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEKIIGNYQNQGFAKFKEDLAEIIITNLQPIRNKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI

Sequences:

>Translated_330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDNNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEKIIGNYQNQGFAKFKEDLAEIIITNLQPIRNKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI
>Mature_330_residues
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIMEVLAVYLAAGLNPDKVTIFA
QSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKACLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIA
GVINRKFNKEILKVPEVLISETGTRIMSLRDGLKKMSKSDISDFSRINLKDNNDLIHQKIKKAKTDHLSFVSYDQETRPE
ISNLLDIYSSLSEESLEKIIGNYQNQGFAKFKEDLAEIIITNLQPIRNKYLELMNDKEYLLKILHKGAEKARIRASETVN
EVKEQFGFVI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=41.6413373860182, Blast_Score=267, Evalue=8e-72,
Organism=Homo sapiens, GI41352700, Length=180, Percent_Identity=50, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=44.8484848484849, Blast_Score=292, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=36.969696969697, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=36.969696969697, Blast_Score=213, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=39.1304347826087, Blast_Score=231, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24666151, Length=327, Percent_Identity=39.4495412844037, Blast_Score=254, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37504; Mature: 37504

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHEEEEEECCHHHHHHHHH
EVLAVYLAAGLNPDKVTIFAQSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFNKEILKVPEVLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGTRIMSLRDGLKKMSKSDISDFSRINLKDNNDLIHQKIKKAKTDHLSFVSYDQETRPE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ISNLLDIYSSLSEESLEKIIGNYQNQGFAKFKEDLAEIIITNLQPIRNKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILHKGAEKARIRASETVNEVKEQFGFVI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKTVLSGVQATGSLHLGNYLGAIKNWVKMQEEYNCFFFLADLHAITVDIKPSELNNSIM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHEEEEEECCHHHHHHHHH
EVLAVYLAAGLNPDKVTIFAQSMVKEHTELAWLLNCVTPLGWLKRMTQFKDKAGSDQEKA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CLGLFSYPVLMAADILIYKADIVPVGEDQKQHLELTRDIAGVINRKFNKEILKVPEVLIS
HHHHHHHHHHHHHHHHHEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGTRIMSLRDGLKKMSKSDISDFSRINLKDNNDLIHQKIKKAKTDHLSFVSYDQETRPE
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ISNLLDIYSSLSEESLEKIIGNYQNQGFAKFKEDLAEIIITNLQPIRNKYLELMNDKEYL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LKILHKGAEKARIRASETVNEVKEQFGFVI
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]