Click here to switch to the map view.

The map label for this gene is iscR [H]

Identifier: 229586808

GI number: 229586808

Start: 705927

End: 706346

Strand: Direct

Name: iscR [H]

Synonym: RAF_ORF0674

Alternate gene names: 229586808

Gene position: 705927-706346 (Clockwise)

Preceding gene: 229586807

Following gene: 229586809

Centisome position: 55.21

GC content: 32.14

Gene sequence:

>420_bases
ATGATGCTGACGACGAAAGGAAGATATGCCGTAATGGCAATACTTGAAATGGCCTCAAAATCAAGTGCCGAACCGGTCAC
TTTGAATGAAATGTCCGTAAAACAAAATATATCGCTTAACTATTTAGAGCAGATATTTTCTAAACTTAAAAAAGCTGATC
TAGTTAAGGCTATTAGAGGATCGAAAGGTGGGTATATTTTAATCGGTAACCTAGAAGAAATAAAAATTTCCGATATTATG
GACGCCGTTAACGAAAATTTTATAATGACTACCTGCTATAAGAAGTCAGTTAAAACTTGCGTGCCTGATACAATAAAATG
TAATTCGCATAAATTATGGCAAGGTCTTGGTAAGCATATTAGAGATTATTTTGAAAATATCTCAATTAAAGATGCTTTAA
ACTCAAATTTAAATATATGA

Upstream 100 bases:

>100_bases
AACAAGCTAATTTTTTATTAAATAATATAATTATATACTTGACTAAATTACTTGGGTATTGTAAATATTAAACAATTTTA
AGTTTTAATAGGTTGGTTAT

Downstream 100 bases:

>100_bases
TATATTTAGACCATAATGCTACTACTTTTATCGACCCTAGAGTTAAGGAATTCATAATAAGTTTAATGGACAAGGAGCTT
AACCCTTCATCAGCACATAG

Product: Iron-sulfur cluster assembly transcription factor IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MMLTTKGRYAVMAILEMASKSSAEPVTLNEMSVKQNISLNYLEQIFSKLKKADLVKAIRGSKGGYILIGNLEEIKISDIM
DAVNENFIMTTCYKKSVKTCVPDTIKCNSHKLWQGLGKHIRDYFENISIKDALNSNLNI

Sequences:

>Translated_139_residues
MMLTTKGRYAVMAILEMASKSSAEPVTLNEMSVKQNISLNYLEQIFSKLKKADLVKAIRGSKGGYILIGNLEEIKISDIM
DAVNENFIMTTCYKKSVKTCVPDTIKCNSHKLWQGLGKHIRDYFENISIKDALNSNLNI
>Mature_139_residues
MMLTTKGRYAVMAILEMASKSSAEPVTLNEMSVKQNISLNYLEQIFSKLKKADLVKAIRGSKGGYILIGNLEEIKISDIM
DAVNENFIMTTCYKKSVKTCVPDTIKCNSHKLWQGLGKHIRDYFENISIKDALNSNLNI

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=39.5522388059701, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15624; Mature: 15624

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLTTKGRYAVMAILEMASKSSAEPVTLNEMSVKQNISLNYLEQIFSKLKKADLVKAIRG
CEECCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SKGGYILIGNLEEIKISDIMDAVNENFIMTTCYKKSVKTCVPDTIKCNSHKLWQGLGKHI
CCCCEEEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RDYFENISIKDALNSNLNI
HHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure
MMLTTKGRYAVMAILEMASKSSAEPVTLNEMSVKQNISLNYLEQIFSKLKKADLVKAIRG
CEECCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
SKGGYILIGNLEEIKISDIMDAVNENFIMTTCYKKSVKTCVPDTIKCNSHKLWQGLGKHI
CCCCEEEECCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RDYFENISIKDALNSNLNI
HHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA