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The map label for this gene is sodB

Identifier: 229586773

GI number: 229586773

Start: 666447

End: 667076

Strand: Direct

Name: sodB

Synonym: RAF_ORF0627

Alternate gene names: 229586773

Gene position: 666447-667076 (Clockwise)

Preceding gene: 229586772

Following gene: 229586774

Centisome position: 52.13

GC content: 33.33

Gene sequence:

>630_bases
ATGACCTATTGCAACAAATCTAATCAAACCTCATATCCTTTTATCTTACCTGATTTACCTTATGAGAAAGAAAGTTTTAA
ACCACATTTTACTCTCGAGACTTTTGATTATCATCATGGTAAGCATCATAATACTTATGTACAAAATCTAAACAATTTAC
TCAAAGATAAAGAAGAATTACAAAAAAAAGATTTAGAAGAAATAATAGAATGGTCATCACAAAACTCAAATGCGGCTATT
TTTAATAACGCAGCCCAAATATGGAATCATACCTTTTTTTGGCATTCAATAAAGCCGCAGGGCGGAGGTAAGCCAAGCGG
TAAAATATTAGAACAAATTAATAAAGATTTCGGTAGTTTTGAAGAGTTTTGCGAACAGTTTAAGCAAGAGGCAGTAGGGC
AATTCGGTAGCGGCTGGGCATGGCTTATATATCACGATAATAGGTTACAAATTATAAAAACCGCTAATGCCGGTACACCT
ATAGCACACGGTATGAAGCCGCTTCTTGCATGTGATGTATGGGAACATGCTTATTATATTGATTATCGTAACAAACGACC
TGATTATGTTGACATATTTATTAAGCATATGATCAACTGGAAGTTTGTAGAAGATAACTTAATAAAATAA

Upstream 100 bases:

>100_bases
GGACTCCTGAGATTGCTTCGTCAAAATTTTCAATTTTTTCTCGCAATGACGTATTGATTCTCGCTATAAATATATAAAAA
CCAACATAGGAGAAAATAAC

Downstream 100 bases:

>100_bases
AACTATGGCTGATATAAAGGTAAGAAAACATCCTATTATTAATAATCTGAAGCAAGAGTCACAAACTCCTGGAGTTAATG
AGCAATCTGATATATTAGAG

Product: Superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHNTYVQNLNNLLKDKEELQKKDLEEIIEWSSQNSNAAI
FNNAAQIWNHTFFWHSIKPQGGGKPSGKILEQINKDFGSFEEFCEQFKQEAVGQFGSGWAWLIYHDNRLQIIKTANAGTP
IAHGMKPLLACDVWEHAYYIDYRNKRPDYVDIFIKHMINWKFVEDNLIK

Sequences:

>Translated_209_residues
MTYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHNTYVQNLNNLLKDKEELQKKDLEEIIEWSSQNSNAAI
FNNAAQIWNHTFFWHSIKPQGGGKPSGKILEQINKDFGSFEEFCEQFKQEAVGQFGSGWAWLIYHDNRLQIIKTANAGTP
IAHGMKPLLACDVWEHAYYIDYRNKRPDYVDIFIKHMINWKFVEDNLIK
>Mature_208_residues
TYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHNTYVQNLNNLLKDKEELQKKDLEEIIEWSSQNSNAAIF
NNAAQIWNHTFFWHSIKPQGGGKPSGKILEQINKDFGSFEEFCEQFKQEAVGQFGSGWAWLIYHDNRLQIIKTANAGTPI
AHGMKPLLACDVWEHAYYIDYRNKRPDYVDIFIKHMINWKFVEDNLIK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family

Homologues:

Organism=Homo sapiens, GI67782307, Length=195, Percent_Identity=43.5897435897436, Blast_Score=150, Evalue=7e-37,
Organism=Homo sapiens, GI67782305, Length=195, Percent_Identity=43.5897435897436, Blast_Score=150, Evalue=7e-37,
Organism=Homo sapiens, GI67782309, Length=195, Percent_Identity=35.3846153846154, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1787946, Length=195, Percent_Identity=52.8205128205128, Blast_Score=221, Evalue=2e-59,
Organism=Escherichia coli, GI1790342, Length=197, Percent_Identity=38.0710659898477, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17506561, Length=199, Percent_Identity=39.6984924623116, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17569479, Length=193, Percent_Identity=39.8963730569948, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321796, Length=200, Percent_Identity=32.5, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136812, Length=189, Percent_Identity=37.5661375661376, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SODF_RICCN (Q92HJ3)

Other databases:

- EMBL:   AE006914
- PIR:   B97797
- RefSeq:   NP_360415.1
- ProteinModelPortal:   Q92HJ3
- SMR:   Q92HJ3
- GeneID:   927465
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0778
- NMPDR:   fig|272944.1.peg.778
- OMA:   WALVNWK
- ProtClustDB:   CLSK870979
- BioCyc:   RCON272944:RC0778-MONOMER
- BRENDA:   1.15.1.1
- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831
- PANTHER:   PTHR11404
- PIRSF:   PIRSF000349
- PRINTS:   PR01703

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N; SSF46609 SODismutase; SSF54719 SODismutase

EC number: =1.15.1.1

Molecular weight: Translated: 24648; Mature: 24517

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHNTYVQNLNNLLKDKEEL
CCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
QKKDLEEIIEWSSQNSNAAIFNNAAQIWNHTFFWHSIKPQGGGKPSGKILEQINKDFGSF
HHHHHHHHHHHCCCCCCEEEECCHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHH
EEFCEQFKQEAVGQFGSGWAWLIYHDNRLQIIKTANAGTPIAHGMKPLLACDVWEHAYYI
HHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCCCHHHCCHHHHHHHHHHHEEEE
DYRNKRPDYVDIFIKHMINWKFVEDNLIK
EECCCCCCHHHHHHHHHHCCEEECCCCCC
>Mature Secondary Structure 
TYCNKSNQTSYPFILPDLPYEKESFKPHFTLETFDYHHGKHHNTYVQNLNNLLKDKEEL
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
QKKDLEEIIEWSSQNSNAAIFNNAAQIWNHTFFWHSIKPQGGGKPSGKILEQINKDFGSF
HHHHHHHHHHHCCCCCCEEEECCHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHH
EEFCEQFKQEAVGQFGSGWAWLIYHDNRLQIIKTANAGTPIAHGMKPLLACDVWEHAYYI
HHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCCCHHHCCHHHHHHHHHHHEEEE
DYRNKRPDYVDIFIKHMINWKFVEDNLIK
EECCCCCCHHHHHHHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893