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The map label for this gene is trxB1 [H]

Identifier: 229586727

GI number: 229586727

Start: 602860

End: 603792

Strand: Direct

Name: trxB1 [H]

Synonym: RAF_ORF0576

Alternate gene names: 229586727

Gene position: 602860-603792 (Clockwise)

Preceding gene: 229586726

Following gene: 229586728

Centisome position: 47.15

GC content: 37.94

Gene sequence:

>933_bases
ATGAAAATTACTACTAAAGTACTAATAATAGGTTCAGGACCTGCGGGCTTAAGTGCCGCTATTTATACAGCTAGAGCTGC
TTTAAAACCAATATTAATAAATGGTATGCAGCCAGGCGGGCAGCTTACAAGTACCACCGATGTTGAGAACTATCCAGGAT
TTGCGGAAACGGTGCAAGGACCTTGGCTTATGGAGCAGATGTATATGCAGGCTAAAAATGTCGGTACGGAAATTGTTAGT
GATTACGTAGAAAAGGTGGATTTATCAAAAAGACCTTTTAAAGTATTTACAGGAGCAGGAAATGAATATGACGCGGAGAG
CATAATCATTTGTACCGGTGCGGAAGCAAAATGGCTTGGTATAGCTTCAGAGCAGAAATTTCGTGGTTTTGGTGTTTCGG
CATGTGCTACTTGCGATGGTTTCTTTTTTAAGAATCAAGAAATAGTTGTAGTAGGGGGAGGAAATAGTGCAGTAGAAGAA
GCTTTATACTTAACCAATCATGCTAACAAAGTCACTATAGTGCATAGAAGAGATAGTTTTAGAGCTGAGAAAATATTACA
GGATCGATTATTTAAAAATTCTAAAATATCAGTAATTTGGGATCATGTAGTAGATGAGATTGTAGGTAGCAATAAACCAA
AATCCGTTACTGGAGTTAAAATTCAAAATGTTCACACCAAAGAGATTAGTCTATTGAATTGTAGTGGTGTATTTATAGCT
ATTGGGCATGCACCGAATACGGGGCTATTTACCGGACAAATTGTAATGGATGACGATAATTATATCATCACGAAGTCAGG
TACTACTAGAACTAGTGTAGAAGGTGTTTTTGCTGCTGGTGACGTTCAGGATAAAATTTATAGACAAGCAGTAACTGCTG
CAGGAACAGGCTGTATGGCGGCTCTTGAGGCTGAAAAATTTCTAAATAAATAA

Upstream 100 bases:

>100_bases
ATACAATAAACATATAAAAAAACTGTTTTTTATATGTTTTTCTGGATTCCTGCTTTCGCATGAATGACATAGGCATCATT
TAAATTAATAAATAATAATT

Downstream 100 bases:

>100_bases
TTTAGATTTTTTAGCTGTAAATTAACATATAAGTTAATAAAAAATTGTTGTATTTAGTAAGACACTTATTATAGTCATTG
TGTATTAATTTAATTAGGTA

Product: Thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTSTTDVENYPGFAETVQGPWLMEQMYMQAKNVGTEIVS
DYVEKVDLSKRPFKVFTGAGNEYDAESIIICTGAEAKWLGIASEQKFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHANKVTIVHRRDSFRAEKILQDRLFKNSKISVIWDHVVDEIVGSNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHAPNTGLFTGQIVMDDDNYIITKSGTTRTSVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK

Sequences:

>Translated_310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTSTTDVENYPGFAETVQGPWLMEQMYMQAKNVGTEIVS
DYVEKVDLSKRPFKVFTGAGNEYDAESIIICTGAEAKWLGIASEQKFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHANKVTIVHRRDSFRAEKILQDRLFKNSKISVIWDHVVDEIVGSNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHAPNTGLFTGQIVMDDDNYIITKSGTTRTSVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK
>Mature_310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTSTTDVENYPGFAETVQGPWLMEQMYMQAKNVGTEIVS
DYVEKVDLSKRPFKVFTGAGNEYDAESIIICTGAEAKWLGIASEQKFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHANKVTIVHRRDSFRAEKILQDRLFKNSKISVIWDHVVDEIVGSNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHAPNTGLFTGQIVMDDDNYIITKSGTTRTSVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=52.7156549520767, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=32.6797385620915, Blast_Score=134, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=46.8354430379747, Blast_Score=281, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=46.6876971608833, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33444; Mature: 33444

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTSTTDVENYPGFAETVQG
CCEEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCC
PWLMEQMYMQAKNVGTEIVSDYVEKVDLSKRPFKVFTGAGNEYDAESIIICTGAEAKWLG
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEE
IASEQKFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEEALYLTNHANKVTIVHRRDSF
ECCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHEECCCCEEEEEEECCCH
RAEKILQDRLFKNSKISVIWDHVVDEIVGSNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEECEEEECEEECEEEEEEECCEEEE
IGHAPNTGLFTGQIVMDDDNYIITKSGTTRTSVEGVFAAGDVQDKIYRQAVTAAGTGCMA
EECCCCCCEEEEEEEEECCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHH
ALEAEKFLNK
HHHHHHHHCC
>Mature Secondary Structure
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTSTTDVENYPGFAETVQG
CCEEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCC
PWLMEQMYMQAKNVGTEIVSDYVEKVDLSKRPFKVFTGAGNEYDAESIIICTGAEAKWLG
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEECCCCEEEE
IASEQKFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEEALYLTNHANKVTIVHRRDSF
ECCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHEECCCCEEEEEEECCCH
RAEKILQDRLFKNSKISVIWDHVVDEIVGSNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEECEEEECEEECEEEEEEECCEEEE
IGHAPNTGLFTGQIVMDDDNYIITKSGTTRTSVEGVFAAGDVQDKIYRQAVTAAGTGCMA
EECCCCCCEEEEEEEEECCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHH
ALEAEKFLNK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]