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The map label for this gene is murG

Identifier: 229586687

GI number: 229586687

Start: 555547

End: 556677

Strand: Direct

Name: murG

Synonym: RAF_ORF0524

Alternate gene names: 229586687

Gene position: 555547-556677 (Clockwise)

Preceding gene: 229586686

Following gene: 229586688

Centisome position: 43.45

GC content: 32.89

Gene sequence:

>1131_bases
ATGAAAAAAATCATTTTGGTAGCAGGAGGGACAGGGGGACATTTTTTTCCGGCAGTTGCTCTTGGAGAAGAATTAATTAA
ACGTGGCTATGAAGTTCATTTTATTACTGATTTAAGATGCAAACAATATATAAAGCAGGATATGAAAGTAATTTTTCATA
TCCTAGATTTAAAACGCTCAGGTAATATTTTCTTGTTTTTACCTAGGTTATCAATTGCAGTTTTAAAGGCTATTAAATTA
TTATATAATATGAAGCCTTCCGTTACTGTAGGGTTTGGCGGTTATCCTGTTATAGCTCCAATGTTTGCAGCAATTTTTTT
AAGAGTACCGATTATAATTCATGAACAGAATTCTTACCTTGGAAAAGTTAATAAATTTTTTGCAAGCTTTGCTAAAAAGA
TAGCTATTTCTTATGAAAAAATAAAGAATTTACCGGAATTTGCAAAAAGTAAAATAGTAGTTACCGGTGGGGTAGTTAGA
GAGAATATTAGGGAATTAAAGGTTATAGAAATGTCGTCCCGTGGCTTGACCACGGGGTCCAAAAAGTCTTTAATAAAAGC
ACTGGATTCCGTGGTTAAGCCACGGAATGACAAGCTTTTTACAATATTCATCTTTGGCGGTAGTCAAGGAGCTAAGTTAT
TTTCAGAGCTGATACCTGCAAGTATCCAATTTTTGATGCAAAAACAGCCAAGTCTTGAATTAAACATAATCCAGCAAGCG
GCATTAGATGATCAAGTAAAAATAAAAGATATATACTCGAAATTAAACATTACCTATGAATTTGCTGAATTTTTTGATAA
TATGGCATTGCAATATAAAGAAGCCGATTTAGTGATTTCAAGAGCAGGAGCATCTACTATAGAAGAATTGACCTATATAG
GGTTGCCGGCAATCTTTATTCCACTGCCTAGTGCTGCAGATAATCATCAATATTACAATGCACAATTATTGGAAGATGAA
AAAACAGGATGGTGTTTAGAGCAGAATAATATTTCTGCAGGAAAATTAGCAGATAAAATACTCGAGTTGATAAGTAATCC
AAAAATATTAGAGGATGCTTCACAAAATTTATTAAAAAGAAGAAAAGAAGGGCATAAGCTATTAAGTAACCTAATAGAAG
AGGTGATTTAG

Upstream 100 bases:

>100_bases
GTTCTTCAACGCTTGCAATAGCTATCGCTACCGGTATGCTTCTTGGCTTTACAAGATACCGAACGCCGTTAAATTCGTAC
AAAATTCGTAATATTGAAAT

Downstream 100 bases:

>100_bases
ATTTTGTTTTCCGTCATTGCGAGGAAAGACTGTAAGTTTTGACGAAGCAATCTCGTGCTAAAGTCCTGAGATTGCCACGC
TCCTTTTAGTCGTTTGTAAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRSGNIFLFLPRLSIAVLKAIKL
LYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYLGKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVR
ENIRELKVIEMSSRGLTTGSKKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQA
ALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAQLLEDE
KTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKRRKEGHKLLSNLIEEVI

Sequences:

>Translated_376_residues
MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRSGNIFLFLPRLSIAVLKAIKL
LYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYLGKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVR
ENIRELKVIEMSSRGLTTGSKKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQA
ALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAQLLEDE
KTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKRRKEGHKLLSNLIEEVI
>Mature_376_residues
MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRSGNIFLFLPRLSIAVLKAIKL
LYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYLGKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVR
ENIRELKVIEMSSRGLTTGSKKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQA
ALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAQLLEDE
KTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKRRKEGHKLLSNLIEEVI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=349, Percent_Identity=28.080229226361, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RICAE (C3PND5)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845188.1
- GeneID:   7814948
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0524
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- InterPro:   IPR022439
- TIGRFAMs:   TIGR01133
- TIGRFAMs:   TIGR03777

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 42186; Mature: 42186

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRS
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
GNIFLFLPRLSIAVLKAIKLLYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYL
CCEEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCEEEECCCCHH
GKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVRENIRELKVIEMSSRGLTTGS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECHHHHHHHHHEEEEEECCCCCCCCH
KKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQA
HHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFI
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEEEHHHEEEECCCCHHHHHHHHHCCCEEEE
PLPSAADNHQYYNAQLLEDEKTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKR
ECCCCCCCCCEECEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RKEGHKLLSNLIEEVI
HHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKKIILVAGGTGGHFFPAVALGEELIKRGYEVHFITDLRCKQYIKQDMKVIFHILDLKRS
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
GNIFLFLPRLSIAVLKAIKLLYNMKPSVTVGFGGYPVIAPMFAAIFLRVPIIIHEQNSYL
CCEEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCEEEECCCCHH
GKVNKFFASFAKKIAISYEKIKNLPEFAKSKIVVTGGVVRENIRELKVIEMSSRGLTTGS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECHHHHHHHHHEEEEEECCCCCCCCH
KKSLIKALDSVVKPRNDKLFTIFIFGGSQGAKLFSELIPASIQFLMQKQPSLELNIIQQA
HHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ALDDQVKIKDIYSKLNITYEFAEFFDNMALQYKEADLVISRAGASTIEELTYIGLPAIFI
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEEEHHHEEEECCCCHHHHHHHHHCCCEEEE
PLPSAADNHQYYNAQLLEDEKTGWCLEQNNISAGKLADKILELISNPKILEDASQNLLKR
ECCCCCCCCCEECEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RKEGHKLLSNLIEEVI
HHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA