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The map label for this gene is cox11

Identifier: 229586561

GI number: 229586561

Start: 409310

End: 409876

Strand: Direct

Name: cox11

Synonym: RAF_ORF0382

Alternate gene names: 229586561

Gene position: 409310-409876 (Clockwise)

Preceding gene: 229586559

Following gene: 229586563

Centisome position: 32.01

GC content: 32.8

Gene sequence:

>567_bases
ATGTCTAAAAAATCCAATAAAAATTTAGCTTTTTCCTTGCTGGGATTAATAATTAGTATGGTGTTACTCAGTTTTGCTTC
CGTACCTATCTATAATTTATTTTGTAAAGTTACAGGATATGGCGGCACTACTGCAAAAGAAACGGTGAGTGTATATTCTA
AGGTAAAAGGCACTAAACCTATAATTATCGAGTTTGATGCTAATGTTGATAAAGATTTACCTTGGCGGTTTATTCCAAGG
CAGCAAAGAGTGCAAATTGTTCCGGGGCAGAATACTCTAGTGTTCTATGAAACGGAGAATCTAAGCGATAACGATATAAT
AGGTACTTCCGTATATAATGTTACTCCAAATAAAGCAGGAAAATATTTCGTAAAAATTCATTGTTTTTGTTTTGAAGAAC
AATTATTAAAAGCCGGCGAAAGAGTCTTAATGCCGGTTACATTTTATATAGATAAGGATTTTGAGCTTGATCCTGAAATG
CAAGACATTAAAGTACTTACTTTATCTTATAGTTTTTTTAAAGTACGAGAGATGTCGTCATTGCGAGGAAATTACGTAAG
TAATTGA

Upstream 100 bases:

>100_bases
ATTATTAGTCATACTAACCTTAAAAACTATTTTTTTTATACTAACACATATATGATCTAAAATAAACTTTTTCTAGAGTA
TTTTTAAATAAAATCAAATA

Downstream 100 bases:

>100_bases
CGAAGCAATCTCAGGAGTTTGTTATTATTTCATGAGATTGCCACGCTCTCTACGTTCGCTCGTAATGACGGCTTTGGAAT
TATGCAACAACACCGGCTCA

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSKKSNKNLAFSLLGLIISMVLLSFASVPIYNLFCKVTGYGGTTAKETVSVYSKVKGTKPIIIEFDANVDKDLPWRFIPR
QQRVQIVPGQNTLVFYETENLSDNDIIGTSVYNVTPNKAGKYFVKIHCFCFEEQLLKAGERVLMPVTFYIDKDFELDPEM
QDIKVLTLSYSFFKVREMSSLRGNYVSN

Sequences:

>Translated_188_residues
MSKKSNKNLAFSLLGLIISMVLLSFASVPIYNLFCKVTGYGGTTAKETVSVYSKVKGTKPIIIEFDANVDKDLPWRFIPR
QQRVQIVPGQNTLVFYETENLSDNDIIGTSVYNVTPNKAGKYFVKIHCFCFEEQLLKAGERVLMPVTFYIDKDFELDPEM
QDIKVLTLSYSFFKVREMSSLRGNYVSN
>Mature_187_residues
SKKSNKNLAFSLLGLIISMVLLSFASVPIYNLFCKVTGYGGTTAKETVSVYSKVKGTKPIIIEFDANVDKDLPWRFIPRQ
QRVQIVPGQNTLVFYETENLSDNDIIGTSVYNVTPNKAGKYFVKIHCFCFEEQLLKAGERVLMPVTFYIDKDFELDPEMQ
DIKVLTLSYSFFKVREMSSLRGNYVSN

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family

Homologues:

Organism=Homo sapiens, GI4758034, Length=184, Percent_Identity=41.304347826087, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI242247061, Length=131, Percent_Identity=35.8778625954198, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI242247057, Length=130, Percent_Identity=36.1538461538462, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71990692, Length=175, Percent_Identity=38.2857142857143, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325125, Length=174, Percent_Identity=41.9540229885057, Blast_Score=156, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24581944, Length=162, Percent_Identity=43.2098765432099, Blast_Score=149, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXZ_RICCN (Q92IL2)

Other databases:

- EMBL:   AE006914
- PIR:   H97750
- RefSeq:   NP_360045.1
- ProteinModelPortal:   Q92IL2
- SMR:   Q92IL2
- GeneID:   927555
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0408
- OMA:   SNNDIIG
- ProtClustDB:   PRK05089
- BioCyc:   RCON272944:RC0408-MONOMER
- HAMAP:   MF_00155
- InterPro:   IPR007533
- Gene3D:   G3DSA:2.60.370.10
- PANTHER:   PTHR21320
- PIRSF:   PIRSF005413

Pfam domain/function: PF04442 CtaG_Cox11; SSF110111 CtaG_Cox11

EC number: NA

Molecular weight: Translated: 21399; Mature: 21268

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2145d038)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKSNKNLAFSLLGLIISMVLLSFASVPIYNLFCKVTGYGGTTAKETVSVYSKVKGTKP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCC
IIIEFDANVDKDLPWRFIPRQQRVQIVPGQNTLVFYETENLSDNDIIGTSVYNVTPNKAG
EEEEECCCCCCCCCEEECCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEECCCCCC
KYFVKIHCFCFEEQLLKAGERVLMPVTFYIDKDFELDPEMQDIKVLTLSYSFFKVREMSS
EEEEEEEEEEEHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEEHHHHHHHHHH
LRGNYVSN
HCCCCCCH
>Mature Secondary Structure 
SKKSNKNLAFSLLGLIISMVLLSFASVPIYNLFCKVTGYGGTTAKETVSVYSKVKGTKP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCC
IIIEFDANVDKDLPWRFIPRQQRVQIVPGQNTLVFYETENLSDNDIIGTSVYNVTPNKAG
EEEEECCCCCCCCCEEECCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEECCCCCC
KYFVKIHCFCFEEQLLKAGERVLMPVTFYIDKDFELDPEMQDIKVLTLSYSFFKVREMSS
EEEEEEEEEEEHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEEHHHHHHHHHH
LRGNYVSN
HCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893