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The map label for this gene is grxC1 [H]

Identifier: 229586448

GI number: 229586448

Start: 273220

End: 273528

Strand: Direct

Name: grxC1 [H]

Synonym: RAF_ORF0249

Alternate gene names: 229586448

Gene position: 273220-273528 (Clockwise)

Preceding gene: 229586446

Following gene: 229586449

Centisome position: 21.37

GC content: 34.95

Gene sequence:

>309_bases
ATGAATAAAGCTATATTACACACAATTATTGTTTATACTCTCTCTAGTTGTCCTTATTGTATAAAAGCTAAAGCATTGCT
TGATGAGAAAAATGTTGCTTATGAGGAAATTGAAGTAAGTAATTTTACTCGGGAAGAGAAAGAAAAATTTATTAAGAAAT
CCGGTGGAAAAAAGACCGTCCCGCAGATATTTATAGATAATATGCATGTTGGCGGTTGTGATGCTCTGTTTGATCTTGAA
AAAGAGGGAAGGTTAGATAAGCTGTTAGAAAATCAGCCAAAGACGACTTCACCTGCTGCTGGAGCGTAA

Upstream 100 bases:

>100_bases
ATATTCTGAGATAATAGAAAAATTATTCATGCATTTTTACTTGCTTTAAAAACTATAGTTTAAGATAATATATTAAAATC
TCACAAAAAAATATAACATT

Downstream 100 bases:

>100_bases
TTAATAAAAACGTCATTGCAAGGAAATTACGAAGTAATTGACGAAGCAATCTAAGGAGTTTGTTATTATTTTATGAGATT
GCCACGCTCCCTACGGTCGC

Product: Glutaredoxin, GrxC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MNKAILHTIIVYTLSSCPYCIKAKALLDEKNVAYEEIEVSNFTREEKEKFIKKSGGKKTVPQIFIDNMHVGGCDALFDLE
KEGRLDKLLENQPKTTSPAAGA

Sequences:

>Translated_102_residues
MNKAILHTIIVYTLSSCPYCIKAKALLDEKNVAYEEIEVSNFTREEKEKFIKKSGGKKTVPQIFIDNMHVGGCDALFDLE
KEGRLDKLLENQPKTTSPAAGA
>Mature_102_residues
MNKAILHTIIVYTLSSCPYCIKAKALLDEKNVAYEEIEVSNFTREEKEKFIKKSGGKKTVPQIFIDNMHVGGCDALFDLE
KEGRLDKLLENQPKTTSPAAGA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=80, Percent_Identity=48.75, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 11375; Mature: 11375

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAILHTIIVYTLSSCPYCIKAKALLDEKNVAYEEIEVSNFTREEKEKFIKKSGGKKTV
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCC
PQIFIDNMHVGGCDALFDLEKEGRLDKLLENQPKTTSPAAGA
CHHHCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNKAILHTIIVYTLSSCPYCIKAKALLDEKNVAYEEIEVSNFTREEKEKFIKKSGGKKTV
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCC
PQIFIDNMHVGGCDALFDLEKEGRLDKLLENQPKTTSPAAGA
CHHHCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]