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The map label for this gene is rpoB [H]

Identifier: 229586379

GI number: 229586379

Start: 179998

End: 184119

Strand: Direct

Name: rpoB [H]

Synonym: RAF_ORF0170

Alternate gene names: 229586379

Gene position: 179998-184119 (Clockwise)

Preceding gene: 229586378

Following gene: 229586380

Centisome position: 14.08

GC content: 34.93

Gene sequence:

>4122_bases
ATGGTTTCATTAAGGGATAATATAGAAGCACAACCCTTGTCACATAATAGAAGAATAAGAAAAAATTTCGGTCACATAAA
TTTAGTAGCAGATATACCGAATTTGATTGAAATTCAAAAAAATTCATATGAGAAAAACTTTCTACAGTTAAATATTAAAG
ATTCTGAAAGAAAAAACAAAGGTTTACAATCTATATTAAACTCGATTTTTCCTATTTCAGATTCCTCCAATATTGCTAAT
TTAGAATTTGTAAAATATGAATTTGATACTCCAAAATATGATGTAGAAGAGTGCAGTCAAAGAAGTTTAAGTTATGCTGC
TCCTCTTAAAGTTACTTTAAGATTAAGTATTTGGGATATAGATGAGGATACCGGTACTAGAGAAATTAAAGGGATTAAAG
AGCAAGAAGTATATATGGGTGATATCCCATTAATGACTAAAAACGGTACTTTTATTATCAATGGTACGGAAAGAGTAGTT
GTATCACAAATGCATCGCTCACCTGGTGTATTCTTTTATCATGATGAAGGAAAAGTCCACTCTTCCGGCAAGCTTTTATA
TTCTGCTCGTGTTATTCCATATAGAGGGTCTTGGCTTGATTTAGAATTCGACGCTAAGGATGTGATTTATTTCAGGATTG
ATAGAAAAAGAAAGCTTTATACTACTACTTTGCTTAGAGCTATAGGTATGAGTACTGAAGAAATTATAAAATTTTATTAT
AATTCAGTAACTTATAAGCTTGTTAAAAATAAAGGTTGGGCGGTTAAATTTATACCTCAGCATATTACTGCTCATCGTTT
AACAAGTGATTTAGTAGATGCAGATACCGGAAATATTCTACTGAAAGCAGGACAAAAAATTACTCCGCGTTTGGCTAAAA
AATATTTTGGGGAAGGGCTTAATAATATTTTAGTAGCTCATGAAACTTTAATCGGCAAATATCTATCCGAAGATTTAAGA
GATCCTGCAAACGATGAAGTATTAGCAAAAATCGGTGAAATGATTACTGCTGATATGCTAAATGTTATTAATGATCTTAA
AATTAAAAATGTTAACGTATTAGTAATCAATCCTCAATCCGGTCCATATATAAGGAACACCTTATTTGCTGATAAAAATC
AGGATCGTGAGGCAGCATTATGTGATATTTTCAGAGTTCTAAGACCAGGCGAACCTGCTAATATCGAAGCGGCTGAAAGC
CTGTTTTATAATTTATTCTTTGATACGGAAAGATATGATCTGTCAGAAGTCGGGCGAATAAAAATGAATTCTAGGTTAGA
GCTGAATATTTCTGAAGAAGTTACGGTTTTAACAATTGATGATATTAAAAATATCGTAAGAGTTTTAGTAGAGCTTAAAG
ACGGTAAAGGTATCATAGACGATATTGATCATTTAGGTAATAGAAGGGTTAGATCGGTAGGTGAATTGATAGAAAATCAA
TTTAGAATAGGTTTAGTCCGAATGGAAAAATCTGTAATTGAAAGGATGTCGGCAGGTGATGTTGATACCGTAATGCCTCA
TGATTTAGTAAATTCTAAAATTTTAGTTTCAGTAGTAAAAGAATTTTTTAGTACCTCCCAATTATCCCAATTTATGGATC
AGACAAATCCATTATCGGAAATAACTCATAAAAGAAGGCTGTCGGCACTCGGTCCCGGAGGTCTTAGTCGAGATCGAGCA
GGTTTTGAGGTGCGTGACGTACATCCGACTCATTACGGTCGTATTTGTCCTATTGAAACACCTGAAGGTCAGAATATCGG
GTTAATTAACTCTATGGCTACTTATGCTAGAATAAATAAACATGGTTTTATAGAGAGTCCGTATAGAAGAGTTAAAGATG
GATGTGTAACCGATGAAGTGGTATATCTTTCTGCTATTGAAGAAGGTAAATACAAAATCGGACAAGCAAATTCTAAAATT
AATAAAGACGGAAAGCTGCAAGGAGAGTTTATTAATTGCCGTGTTGAAGGCGGTAATTTTGTAATGGTAGAACCGTATGA
GGTAGACTTCATTGATGTGACTCCTATGCAGGTAGTATCGGTTGCAGCTTCTCTTATACCTTTCTTAGAAAACGATGATG
CTAACCGTGCTTTGATGGGTTCAAACATGCAAAGACAAGCCGTTCCTTTAATTAAAACGGATGCACCTTTTGTAGGTACC
GGAGTTGAAGGGATAGTAGCTAAAGATTCCGGAGCGTCAGTGCTTGCATTACATGACGGTATTGTTGAGCAGGTAGATTC
AAATAGAATCGTGATTAGAACTCTAGAACAAAAAGTTGACGGTTCTCCTTCGGTTGATATTTATAACTTACTAAAATTCC
AAAAATCCAATCATAATACTTGTATAAATCAAAAGCCTTTAGTTAAGGTCGGTCATTACGTTAAGAAAAACGATATTATA
GCTGACGGTCCTAGTACGGATAACGGTGAAATTGCTTTAGGTCGAAACGTGCTTGTGGCTTTCTTACCTTGGAACGGTTA
TAATTTTGAAGATTCCATTTTAATATCCGAACGTATAGTAAAAGAGGATGTATTTACATCTATTCATATTGAAGAGTTTG
AAGTAATAGCTAGAGATACACGTCTTGGTCCTGAAGAAATTACCCGTGATATACCGAATGTAAGTGAAGAAGCGTTGCGT
CATCTTGATGAGGTCGGAATAATTTATATAGGTGCAGAAGTAAAAGCCGGTGATATTTTAGTTGGAAAAGTAACACCAAA
AAGTGAATCGCCTATTACTCCTGAAGAGAAGCTACTACGTGCTATTTTCGGGGAAAAAGCTTTTGACGTAAAAGATTCAT
CGCTGCATGTACCTTCCGGAGTGAGCGGAACTGTAGTAGAAGTAAGGGTATTTTCTCGTAGAGGTGTAGAAAAAGACCAG
CGAGCTATTGCTATTGAAAAACAACAAATTGAAAAATTCGCAAAAGACAGAGACGATGAATTAGAAATTATTGAGCATTT
TGTGTTTAGTTGGCTTGAAAAGCTTTTAGTAGGGCAGGTGATTATTAACGGTCCTAAGCAAGTAAAAGTAGGACAAACTA
TTACTACTGAAATGCTAAAAGGCTTATCTAAAGGGCAATTTTGGCAGATTATCGTGGAAGATGCAAATGTAATGAATGAA
ATAGAGCAGATAAAGACTCATTATGATGAGAAAAAAGAGGCTCTTGATAAAAGATTTGCTACTAAGGTAGAGAAATTGCA
AAGTGGTGATGATTTACCTCAGGGAGCTTTAAAAGTAGTAAAAGTATTTATTGCCACTAAGCATAAATTACAACCTGGGG
ATAAAATGGCAGGAAGACACGGAAATAAAGGTGTTATTTCACGTATCGTACCTGAAGAAGATATGCCGTTTTTAGAAGAT
GGAACTGTGGTAGATATCGTTCTTAACCCTCTAGGTCTTCCGTCCCGTATGAATATAGGACAGATTTTAGAAACGCATCT
TGGGTGGGCATCAATAAATTTAGCAAAAAAAATATCTACCTTAGTAAAGGAATATAAAAATAAACATATAGGTATTGAGC
AGATTAAGAAATTCTTAATTGAACTGTATGGAGAAAATATTAATTCTATACTTGAAAGACCGGAAGAAGAGATTATCTCT
TTTTGTAAGAAAGTAAGTAAAGGCGTACATTTTGCAACTCCTGTATTTGACGGAGCAAAAGTTCAGGACGTTAAAGATAT
GTTAAAGCTTGCCGGTCAAGACCCTTCAGGACAAGTGAAATTAATTGACGGTAGAACCGGTGAATATTTTGACCGTCTAG
TAACCGTCGGACAGAAATATTTGTTGAAATTGCATCATTTAGTCGATAATAAAATTCATTCCCGTTCTATAGGACCTTAT
AGCTTAGTAACGCAGCAACCGCTTGGAGGTAAGTCTCATTTCGGCGGACAGCGTTTCGGAGAAATGGAATGCTGGGCATT
ACAAGCTTACGGTGCAGCTTATACGTTACAGGAAATGTTAACGGTTAAGTCGGATGACGTAAACGGTAGGATTAAAACTT
ATGATTCTATAGTACGTGGTGAAAATAATTTTGAATCAGGCATTCCTGAATCATTTAATGTTATGATAAAAGAATTTAGA
TCTTTATGTCTTAACGTAAAGCTTGAAGTAACTTCAAGTTAA

Upstream 100 bases:

>100_bases
TTTACAGCTAAAAAGAGCCATAATTATGATTATTCTATTAAAAGTGCATAGGACCTAATCACTGTAATACGGGCAGTAAT
TTTATCAGTCAGGAGATTAT

Downstream 100 bases:

>100_bases
GAAAGACAGGTCATTTAAACAGATAAAAAACAAGTTTTTTATCTGTTTTACTAGATTCCCGCTTTTGCGGGAATGACATA
TAGGGTGCAATAAGAACTCT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1373; Mature: 1373

Protein sequence:

>1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYTTTLLRAIGMSTEEIIKFYY
NSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGLNNILVAHETLIGKYLSEDLR
DPANDEVLAKIGEMITADMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAES
LFYNLFFDTERYDLSEVGRIKMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKI
NKDGKLQGEFINCRVEGGNFVMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGIVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNTCINQKPLVKVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYIGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKFAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLKGLSKGQFWQIIVEDANVMNE
IEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIIS
FCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS

Sequences:

>Translated_1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYTTTLLRAIGMSTEEIIKFYY
NSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGLNNILVAHETLIGKYLSEDLR
DPANDEVLAKIGEMITADMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAES
LFYNLFFDTERYDLSEVGRIKMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKI
NKDGKLQGEFINCRVEGGNFVMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGIVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNTCINQKPLVKVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYIGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKFAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLKGLSKGQFWQIIVEDANVMNE
IEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIIS
FCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS
>Mature_1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYTTTLLRAIGMSTEEIIKFYY
NSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGLNNILVAHETLIGKYLSEDLR
DPANDEVLAKIGEMITADMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAES
LFYNLFFDTERYDLSEVGRIKMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKI
NKDGKLQGEFINCRVEGGNFVMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGIVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNTCINQKPLVKVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYIGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKFAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLKGLSKGQFWQIIVEDANVMNE
IEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIIS
FCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908503, Length=303, Percent_Identity=29.7029702970297, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI238908505, Length=303, Percent_Identity=29.7029702970297, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI33469941, Length=261, Percent_Identity=31.8007662835249, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI212286172, Length=261, Percent_Identity=31.8007662835249, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI4505941, Length=315, Percent_Identity=30.1587301587302, Blast_Score=120, Evalue=8e-27,
Organism=Escherichia coli, GI1790419, Length=1363, Percent_Identity=54.1452677916361, Blast_Score=1491, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=303, Percent_Identity=27.7227722772277, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17552304, Length=248, Percent_Identity=31.8548387096774, Blast_Score=111, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=305, Percent_Identity=30.8196721311475, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=252, Percent_Identity=31.3492063492063, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=249, Percent_Identity=31.7269076305221, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136444, Length=310, Percent_Identity=29.0322580645161, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17647877, Length=247, Percent_Identity=28.7449392712551, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136446, Length=100, Percent_Identity=39, Blast_Score=71, Evalue=6e-12,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154373; Mature: 154373

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH
GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC
DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH
CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE
SSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYTTTLLRAIGMSTEEIIKFYY
CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
NSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGL
HHHEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCH
NNILVAHETLIGKYLSEDLRDPANDEVLAKIGEMITADMLNVINDLKIKNVNVLVINPQS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC
GPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAESLFYNLFFDTERYDLSEVGRI
CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCCCHHHCCEE
KMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
EECCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
HGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKINKDGKLQGEFINCRVEGGNF
CCCCCCHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEECCCE
VMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
EEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC
GVEGIVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNT
CCCEEEEECCCCEEEEECCHHHHHCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHCCCCCC
CINQKPLVKVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV
CCCCCCHHHHCCEEECCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH
KEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYIGAEVKAGDIL
HHHHHHEEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE
VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH
RAIAIEKQQIEKFAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHH
GLSKGQFWQIIVEDANVMNEIEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVV
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG
HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIIS
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
FCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY
HHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML
HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH
TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS
HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC
>Mature Secondary Structure
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH
GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC
DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH
CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE
SSGKLLYSARVIPYRGSWLDLEFDAKDVIYFRIDRKRKLYTTTLLRAIGMSTEEIIKFYY
CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
NSVTYKLVKNKGWAVKFIPQHITAHRLTSDLVDADTGNILLKAGQKITPRLAKKYFGEGL
HHHEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCH
NNILVAHETLIGKYLSEDLRDPANDEVLAKIGEMITADMLNVINDLKIKNVNVLVINPQS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC
GPYIRNTLFADKNQDREAALCDIFRVLRPGEPANIEAAESLFYNLFFDTERYDLSEVGRI
CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCCCHHHCCEE
KMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
EECCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
HGFIESPYRRVKDGCVTDEVVYLSAIEEGKYKIGQANSKINKDGKLQGEFINCRVEGGNF
CCCCCCHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEECCCE
VMVEPYEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
EEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC
GVEGIVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKVDGSPSVDIYNLLKFQKSNHNT
CCCEEEEECCCCEEEEECCHHHHHCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHCCCCCC
CINQKPLVKVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV
CCCCCCHHHHCCEEECCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH
KEDVFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYIGAEVKAGDIL
HHHHHHEEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE
VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH
RAIAIEKQQIEKFAKDRDDELEIIEHFVFSWLEKLLVGQVIINGPKQVKVGQTITTEMLK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHH
GLSKGQFWQIIVEDANVMNEIEQIKTHYDEKKEALDKRFATKVEKLQSGDDLPQGALKVV
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KVFIATKHKLQPGDKMAGRHGNKGVISRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG
HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QILETHLGWASINLAKKISTLVKEYKNKHIGIEQIKKFLIELYGENINSILERPEEEIIS
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
FCKKVSKGVHFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY
HHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML
HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH
TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS
HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9555894; 9823893; 10508014 [H]