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The map label for this gene is argS

Identifier: 229586306

GI number: 229586306

Start: 87835

End: 89565

Strand: Direct

Name: argS

Synonym: RAF_ORF0089

Alternate gene names: 229586306

Gene position: 87835-89565 (Clockwise)

Preceding gene: 229586305

Following gene: 229586307

Centisome position: 6.87

GC content: 33.16

Gene sequence:

>1731_bases
ATGAATATATTTAATCAATTGAAACAAGATATAATTGTGGCAAGCAGGCAATTATATAATAATCAAGAAATAGCAAATAC
TGCTACTATTGAAATACCGAAAGATAGTTTTAACGGTGATTTATCAAGTAATATTGCAATGATTATTGCAGCTAAAGAAA
GTATTGCTCCTCGGGAAGTGGCTTTAAAATTTAAAGAAGTCCTTATAACATTACCTTATATTGCAAGTATAGAAATAGCA
GGACCTGGCTTTATTAATTTTACTATAAAAGCTGATAGTTGGCAGGCATCAATAAAGGATATTTTACAGCATGAAGAAAA
GTTTTTTGAAATTGATATAGATAAAAGCAAAAATATTAACATCGAGTATGTTTCGGCAAATCCCACCGGTCCAATGCATA
TAGGGCATGCTAGGGGTGCGATATATGGTGATGTGCTAGCAAGGATTTTGCAAAAGGTAAGTTATTCCGTTACAAAAGAA
TATTATGTTAATGATGCAGGCTCACAAATAAATGATTTAGTTAGTACGGTATTATTACGTTATAAAGAGGCTTTAGGTGA
GCAAATTACTATCCCTGCCGGGTTATATCCGGGAGAGTATTTAATTCCGCTTGGGCAAATTTTAGCGAAAGAATACGGCA
ATAAATTATTAACGATGAACTATGCTGAAAGGTTCAAAATAATTAAAAGTTTTGCCGTAGAAAAAATGCTTGATTTAAAT
AGAAAAGATTTAGCAGATTTAGGGATTAAACATGATATATTTTTCTCTGAGCAATCATTGCATGATAAAGGTGAGATAGA
GGAAACAGTTAAACTACTGGAGCGTATGGGGCTAATTTATGAAGGTACGTTACCTGCCCCTAAAGGTAAAATTCACGAAG
AGTGGGATAATAGAGTTCAAAAATTATTTAAATCTACTAAGTACGGTGATAGTCAAGATCGTCCTATAGAAAAAGCTGAT
GGAAGTTGGTCTTATTTTGCTTCTGATCTTGCATATGCTAAGGATAAAATAGAGCGGGGAGCGAATCACTTAATTTATGT
ACTTGGTGCCGATCATAGTGGATATGTTAAAAGAATTGAGGCAATAGTTAAAGCTTTAGGTAAGGAGCAGGTTAAAGTGG
ACGTTAAAATTTGTCAATTGGTCAATTTCGTTGAAAACGGTGTGCCGGTTAAAATGTCAAAACGTCTTGGGAGCTTTGCT
AGTGTGCAAGACGTAAATCATGAGGTGGGGAAAGATATCATAAGATTTATGATGTTAACTAGACAAAATGATAAGCCACT
TGATTTTGATTTGGTAAAAGTGAAAGAACAATCAAGAGAAAATCCTATCTTTTATGTACAATATGCACATGTGAGAACGA
TATCTATTTTATCAAAAGCTAAAGAATTAATGCCTGAATCTTATAATAACTTTGAATCAGGTAAGTATGATTTATCTTTA
TTATCCTCTGAAGAAGAAATTGAGATTATAAAACTTTTGGCTAGTTGGACAAAAACATTAGAAGCATCTGCAAAATATTT
TGAACCGCATCGCATCGCATTTTATTTAATAAATTTAGCCTCAAAATTTCATTCTATGTGGAATTTCGGTAAAGAAAATA
GCGATTATAGATTTGTAATTGAGAGCAATAAAGAATTAACTCTAGCACGCCTTGCTCTTGCAAGTGCCATACAGAAAGTT
ATAGCTAGCGGTCTCGAAGTGATAGGTGTAGAACCAATGAACAAAATGTAG

Upstream 100 bases:

>100_bases
TACGCTACGGTGCTGCGTTCTGTGTCTCCTACAAATTCCTCCTTATTAGCAAGCGTTTGTAAGAATTCTATTCGCTGAAT
TTTAATAACATTTAATAATT

Downstream 100 bases:

>100_bases
TTAGGTTTTCATCGTCATTGCAAGGAGGTATTGCTCATGTGGATACCGAGTCGTCATTGTGAGCAGCCGTAGGCTGCGTG
GCAATCTCATGAAATAATAC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNIAMIIAAKESIAPREVALKFKEVLITLPYIASIEIA
GPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSKNINIEYVSANPTGPMHIGHARGAIYGDVLARILQKVSYSVTKE
YYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIIKSFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKAKELMPESYNNFESGKYDLSL
LSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVIESNKELTLARLALASAIQKV
IASGLEVIGVEPMNKM

Sequences:

>Translated_576_residues
MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNIAMIIAAKESIAPREVALKFKEVLITLPYIASIEIA
GPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSKNINIEYVSANPTGPMHIGHARGAIYGDVLARILQKVSYSVTKE
YYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIIKSFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKAKELMPESYNNFESGKYDLSL
LSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVIESNKELTLARLALASAIQKV
IASGLEVIGVEPMNKM
>Mature_576_residues
MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNIAMIIAAKESIAPREVALKFKEVLITLPYIASIEIA
GPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSKNINIEYVSANPTGPMHIGHARGAIYGDVLARILQKVSYSVTKE
YYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIIKSFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKAKELMPESYNNFESGKYDLSL
LSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVIESNKELTLARLALASAIQKV
IASGLEVIGVEPMNKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=605, Percent_Identity=21.9834710743802, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1788184, Length=618, Percent_Identity=23.6245954692557, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320548, Length=570, Percent_Identity=25.7894736842105, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321883, Length=575, Percent_Identity=23.304347826087, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859963, Length=606, Percent_Identity=22.9372937293729, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RICAE (C3PMA4)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002844807.1
- ProteinModelPortal:   C3PMA4
- GeneID:   7815340
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0089
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65221; Mature: 65221

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNIAMIIAAKESIAPREV
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCHHHH
ALKFKEVLITLPYIASIEIAGPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSKNIN
HHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCC
IEYVSANPTGPMHIGHARGAIYGDVLARILQKVSYSVTKEYYVNDAGSQINDLVSTVLLR
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIIKSFAVEKMLDLN
HHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCC
RKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQ
HHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHH
KLFKSTKYGDSQDRPIEKADGSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIE
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
AIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNHEVGKDIIRFMMLT
HHHHHHCCHHEEHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKAKELMPESYNNFESGKYDLSL
CCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
LSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ESNKELTLARLALASAIQKVIASGLEVIGVEPMNKM
ECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNIAMIIAAKESIAPREV
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCHHHH
ALKFKEVLITLPYIASIEIAGPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSKNIN
HHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCC
IEYVSANPTGPMHIGHARGAIYGDVLARILQKVSYSVTKEYYVNDAGSQINDLVSTVLLR
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIIKSFAVEKMLDLN
HHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHCCC
RKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQ
HHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHH
KLFKSTKYGDSQDRPIEKADGSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIE
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
AIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNHEVGKDIIRFMMLT
HHHHHHCCHHEEHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKAKELMPESYNNFESGKYDLSL
CCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
LSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ESNKELTLARLALASAIQKVIASGLEVIGVEPMNKM
ECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA