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The map label for this gene is dmsB [H]

Identifier: 227828791

GI number: 227828791

Start: 2384576

End: 2385772

Strand: Direct

Name: dmsB [H]

Synonym: M1425_2565

Alternate gene names: 227828791

Gene position: 2384576-2385772 (Clockwise)

Preceding gene: 227828789

Following gene: 227828792

Centisome position: 91.4

GC content: 35.67

Gene sequence:

>1197_bases
ATGGAAAGGAAATTAGGATTCATATTTGACCATAATAAGTGCATAATCTGTAACGCTTGCGTTGATGCTTGCAATAAAGC
TTATGGTAACCTTAACTGGAGAAGCTTAATCGTGATGCCATATGGTGAGAGTAAAACAGCGCTCTCAATTGCTTGTAATC
ATTGCGATAATCCAACGTGTATGCAAGTATGCCCCGCTAATGCAATAGAGAAGAACGAAATGGGAATAGTCAGAATAAGA
GATGATAAATGTATAGGATGTGGATTCTGTACGTGGGCTTGTCCATATGAGGCTTTAAAGTTCAATAATGAAGGAATCAT
GACTAAATGCAACTTTTGTTATGCTCGTTTAGCAGAGGGAAAGGGCATACCATACTGTGTCGAAGCTTGTCCCACAGGGG
CATTAGCATTTGGCTGGATAGAGAAAGGAGAGGCAGAAGTAGATTATCTTCCTCCCTCGGAGATAACTAAACCAAGGATA
GTAATAAAACAACCAGAAATAAAGGAGAGCCTTAAAGCAAATGTTTTACATACTAAAAAGGAGGACAATTACTTGGGACT
ATTAGCTTTTACAATTGGGAGTGAATTCGCGTTGGGTTATTCTCTCTTTAAATTGCCATTCTGGAGTATTGTAAGCGTTA
TCTTACTAGTAGCTTCTTTACTCTTATCAGTAAATCACGCTAGGAGAACTGATAGGTTTTACAGAGTTATTTACAACTTG
AAGACATCTTGGTTAAGCAGAGAAGTATTATTTTCATCCTTATCGATACTATTCTATATCTTAAGTATAGTCAAACCCGC
ATTTTACTATCCCGCGTTAGTATTTCTAACCGCTGGAGTTATCTCAAGTATTATGATCTATATGTTGAAAAGTAGACCGT
CGTGGTATAAGGCTGATACTCCAGTTTCCTTCGTAGGGAGTATCTTTACAATGTCTCTACCAATTGCGTACTTTTTAACC
CACGATCTAATAACTATTATTCCATTAGTGATAATATTAGCTATAGAAATAATCTCTAATCACATGAGGTCTAAAGTTAG
AACGAGCCTCAACATTGTTTCGATTCTCATCTCATTAATTTCAATCATAATTCCTGAAATTATCATTATAGTTGAAATTA
TGAATATTGTTTCTGAAACCGAACATAGGAAAGAGTTTTATGAAAAAGTTATATATTACGGCTTACCTAAAGTTTAA

Upstream 100 bases:

>100_bases
TCATTAATGCGTATTTGTAAAATGGTGTTTCCATAAAATTTAATCAATTTATATCGATATAAAGCTAATGTTATTAACCT
ATTTTACGAGATATTAACAT

Downstream 100 bases:

>100_bases
ACATTTTTTATAGTTAGTTTTTTAAACGATGAAGAGTATACAGTTCTAATAGGTGGTTATTTATTGCTCGAAATAAGATT
CCACGGTAGAGGTGGACAAG

Product: 4Fe-4S ferredoxin iron-sulfur binding domain protein

Products: NA

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MERKLGFIFDHNKCIICNACVDACNKAYGNLNWRSLIVMPYGESKTALSIACNHCDNPTCMQVCPANAIEKNEMGIVRIR
DDKCIGCGFCTWACPYEALKFNNEGIMTKCNFCYARLAEGKGIPYCVEACPTGALAFGWIEKGEAEVDYLPPSEITKPRI
VIKQPEIKESLKANVLHTKKEDNYLGLLAFTIGSEFALGYSLFKLPFWSIVSVILLVASLLLSVNHARRTDRFYRVIYNL
KTSWLSREVLFSSLSILFYILSIVKPAFYYPALVFLTAGVISSIMIYMLKSRPSWYKADTPVSFVGSIFTMSLPIAYFLT
HDLITIIPLVIILAIEIISNHMRSKVRTSLNIVSILISLISIIIPEIIIIVEIMNIVSETEHRKEFYEKVIYYGLPKV

Sequences:

>Translated_398_residues
MERKLGFIFDHNKCIICNACVDACNKAYGNLNWRSLIVMPYGESKTALSIACNHCDNPTCMQVCPANAIEKNEMGIVRIR
DDKCIGCGFCTWACPYEALKFNNEGIMTKCNFCYARLAEGKGIPYCVEACPTGALAFGWIEKGEAEVDYLPPSEITKPRI
VIKQPEIKESLKANVLHTKKEDNYLGLLAFTIGSEFALGYSLFKLPFWSIVSVILLVASLLLSVNHARRTDRFYRVIYNL
KTSWLSREVLFSSLSILFYILSIVKPAFYYPALVFLTAGVISSIMIYMLKSRPSWYKADTPVSFVGSIFTMSLPIAYFLT
HDLITIIPLVIILAIEIISNHMRSKVRTSLNIVSILISLISIIIPEIIIIVEIMNIVSETEHRKEFYEKVIYYGLPKV
>Mature_398_residues
MERKLGFIFDHNKCIICNACVDACNKAYGNLNWRSLIVMPYGESKTALSIACNHCDNPTCMQVCPANAIEKNEMGIVRIR
DDKCIGCGFCTWACPYEALKFNNEGIMTKCNFCYARLAEGKGIPYCVEACPTGALAFGWIEKGEAEVDYLPPSEITKPRI
VIKQPEIKESLKANVLHTKKEDNYLGLLAFTIGSEFALGYSLFKLPFWSIVSVILLVASLLLSVNHARRTDRFYRVIYNL
KTSWLSREVLFSSLSILFYILSIVKPAFYYPALVFLTAGVISSIMIYMLKSRPSWYKADTPVSFVGSIFTMSLPIAYFLT
HDLITIIPLVIILAIEIISNHMRSKVRTSLNIVSILISLISIIIPEIIIIVEIMNIVSETEHRKEFYEKVIYYGLPKV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787872, Length=185, Percent_Identity=42.7027027027027, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787122, Length=186, Percent_Identity=41.9354838709677, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI2367345, Length=158, Percent_Identity=36.0759493670886, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI226510944, Length=156, Percent_Identity=35.8974358974359, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789370, Length=198, Percent_Identity=33.8383838383838, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787749, Length=156, Percent_Identity=33.974358974359, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790326, Length=165, Percent_Identity=32.7272727272727, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082180, Length=130, Percent_Identity=36.1538461538462, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787740, Length=81, Percent_Identity=44.4444444444444, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787478, Length=81, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI2367245, Length=147, Percent_Identity=32.6530612244898, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788811, Length=142, Percent_Identity=27.4647887323944, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082179, Length=141, Percent_Identity=31.2056737588652, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 44963; Mature: 44963

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKLGFIFDHNKCIICNACVDACNKAYGNLNWRSLIVMPYGESKTALSIACNHCDNPTC
CCCCCCEEEECCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCCH
MQVCPANAIEKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGIMTKCNFCYARLAEG
HHCCCCCCCCCCCCCEEEECCCCEEECCCHHHHCCHHHHEECCCCCEEEHHHHHHHHHCC
KGIPYCVEACPTGALAFGWIEKGEAEVDYLPPSEITKPRIVIKQPEIKESLKANVLHTKK
CCCCHHHHHCCCCCEEEHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
EDNYLGLLAFTIGSEFALGYSLFKLPFWSIVSVILLVASLLLSVNHARRTDRFYRVIYNL
CCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSWLSREVLFSSLSILFYILSIVKPAFYYPALVFLTAGVISSIMIYMLKSRPSWYKADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVSFVGSIFTMSLPIAYFLTHDLITIIPLVIILAIEIISNHMRSKVRTSLNIVSILISLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIIPEIIIIVEIMNIVSETEHRKEFYEKVIYYGLPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERKLGFIFDHNKCIICNACVDACNKAYGNLNWRSLIVMPYGESKTALSIACNHCDNPTC
CCCCCCEEEECCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCCCH
MQVCPANAIEKNEMGIVRIRDDKCIGCGFCTWACPYEALKFNNEGIMTKCNFCYARLAEG
HHCCCCCCCCCCCCCEEEECCCCEEECCCHHHHCCHHHHEECCCCCEEEHHHHHHHHHCC
KGIPYCVEACPTGALAFGWIEKGEAEVDYLPPSEITKPRIVIKQPEIKESLKANVLHTKK
CCCCHHHHHCCCCCEEEHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCC
EDNYLGLLAFTIGSEFALGYSLFKLPFWSIVSVILLVASLLLSVNHARRTDRFYRVIYNL
CCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSWLSREVLFSSLSILFYILSIVKPAFYYPALVFLTAGVISSIMIYMLKSRPSWYKADT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVSFVGSIFTMSLPIAYFLTHDLITIIPLVIILAIEIISNHMRSKVRTSLNIVSILISLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIIPEIIIIVEIMNIVSETEHRKEFYEKVIYYGLPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S clusters [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]