Click here to switch to the map view.

The map label for this gene is yajO [H]

Identifier: 227828588

GI number: 227828588

Start: 2165829

End: 2166854

Strand: Direct

Name: yajO [H]

Synonym: M1425_2342

Alternate gene names: 227828588

Gene position: 2165829-2166854 (Clockwise)

Preceding gene: 227828586

Following gene: 227828590

Centisome position: 83.02

GC content: 38.4

Gene sequence:

>1026_bases
ATGAAGTATATTAAATTAGGTGATTCTGGAGTTAAGGTATCTCAAGTTGCTATAGGTACGTGGTTTCTTCCTAGATTACA
AGAGAAGGACGAACTAGGTATACATAAAGTGGATAAAGAAACTACATTAAAGATCCTTAAAAGAGCGTATGATGAGGGAG
TTAACTTCATAGATACTGCAAATAGATATCACGGCGCTATGGCACCAGTGGATTTGGCACATGTAGGTAATGCCGAGCGC
ATTGTTGGAGAATTTCTAAAAACTGTGAATAGGGAATCTGTCGTAATTTCGACTAAGGTTAGGGGTAAGATGGGTGACTT
CGCTAATGGAGAAGGTTTGTCTAGGAAACATATACAATGGCAAATTAAGGAAAGCTTGAAAAGGTTAGGCACATCATACA
TAGATCTCTATTTCATCCATTGGCCAGATCCCGATACTCCCAAGCTGGAAACCCTAAGAACACTGAATAGTTTAGTGAAC
AATGGCTTAGTTTATTATTTGGGCGTTAGTAATCATTCTGCAATTGATGTGATGGAATTCCTACATTTAAGTGAGAGGTA
TAACTTGGAGAAATTCGTGGTAATGCAAGAGAAATACAACATGTTGGAAAGGGATATAGAGAAAGATAAGGTTGATATCG
CAAGAAGGTATGGATTAGCAGTTATGGCTTATTCACCGTTAGCTCAAGGGTTTCTCACTGGAAAGTATACGGATAGAAAT
GGTTGGAAGGTTGAGGAACTTAGTAGAGCTACTATAAGTGAAGACTTAAAGAAAAGATACTTTACCGACGCTAATTTAAA
GATATTATTGGGGCTTAAGGATATTGCATCAGAACTGGGGATAACCCTGTCCCAATTGGCTATCGCGTGGCTTCTCAAGA
GAGGTGAACAGCTCGGTGTTACAGTAATCCCACTTATTGGAGCCAGTAAAGTTGAGCATTTAGAGGACAACCTATCTGCG
TTAAATGTGAATTTGAGAGATGAACATATGAAAAGAATAGAGGAAATATTAGGAAAATCCACATGA

Upstream 100 bases:

>100_bases
TTTAAGACTTGAATATCCAAACGATTGGAAGTATCTGCAAAAGGTAAAAGGATATAGTGTTTTTTGAAACTATAAATAGC
TGTATTCTCGTTTTACATAT

Downstream 100 bases:

>100_bases
CTTGTAAACGTCAAGAGCTGCTCTTAAATCCCTCAAGGCAATTTCAGGTGGCATAGGTACTTCAGTATTGTTTTTCACAG
CGTTTACAAATCCCCTTATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKYIKLGDSGVKVSQVAIGTWFLPRLQEKDELGIHKVDKETTLKILKRAYDEGVNFIDTANRYHGAMAPVDLAHVGNAER
IVGEFLKTVNRESVVISTKVRGKMGDFANGEGLSRKHIQWQIKESLKRLGTSYIDLYFIHWPDPDTPKLETLRTLNSLVN
NGLVYYLGVSNHSAIDVMEFLHLSERYNLEKFVVMQEKYNMLERDIEKDKVDIARRYGLAVMAYSPLAQGFLTGKYTDRN
GWKVEELSRATISEDLKKRYFTDANLKILLGLKDIASELGITLSQLAIAWLLKRGEQLGVTVIPLIGASKVEHLEDNLSA
LNVNLRDEHMKRIEEILGKST

Sequences:

>Translated_341_residues
MKYIKLGDSGVKVSQVAIGTWFLPRLQEKDELGIHKVDKETTLKILKRAYDEGVNFIDTANRYHGAMAPVDLAHVGNAER
IVGEFLKTVNRESVVISTKVRGKMGDFANGEGLSRKHIQWQIKESLKRLGTSYIDLYFIHWPDPDTPKLETLRTLNSLVN
NGLVYYLGVSNHSAIDVMEFLHLSERYNLEKFVVMQEKYNMLERDIEKDKVDIARRYGLAVMAYSPLAQGFLTGKYTDRN
GWKVEELSRATISEDLKKRYFTDANLKILLGLKDIASELGITLSQLAIAWLLKRGEQLGVTVIPLIGASKVEHLEDNLSA
LNVNLRDEHMKRIEEILGKST
>Mature_341_residues
MKYIKLGDSGVKVSQVAIGTWFLPRLQEKDELGIHKVDKETTLKILKRAYDEGVNFIDTANRYHGAMAPVDLAHVGNAER
IVGEFLKTVNRESVVISTKVRGKMGDFANGEGLSRKHIQWQIKESLKRLGTSYIDLYFIHWPDPDTPKLETLRTLNSLVN
NGLVYYLGVSNHSAIDVMEFLHLSERYNLEKFVVMQEKYNMLERDIEKDKVDIARRYGLAVMAYSPLAQGFLTGKYTDRN
GWKVEELSRATISEDLKKRYFTDANLKILLGLKDIASELGITLSQLAIAWLLKRGEQLGVTVIPLIGASKVEHLEDNLSA
LNVNLRDEHMKRIEEILGKST

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=34.4827586206897, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI4504825, Length=346, Percent_Identity=34.393063583815, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI27436964, Length=331, Percent_Identity=36.8580060422961, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI27436962, Length=331, Percent_Identity=36.5558912386707, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=36.7469879518072, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI27436971, Length=354, Percent_Identity=34.180790960452, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI41152114, Length=221, Percent_Identity=33.0316742081448, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI223718702, Length=296, Percent_Identity=28.3783783783784, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI41327764, Length=234, Percent_Identity=31.1965811965812, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI87081735, Length=340, Percent_Identity=34.1176470588235, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=32.5373134328358, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788070, Length=356, Percent_Identity=30.8988764044944, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=30.7262569832402, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788081, Length=325, Percent_Identity=27.6923076923077, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=359, Percent_Identity=30.6406685236769, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=310, Percent_Identity=30.6451612903226, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323998, Length=310, Percent_Identity=30.3225806451613, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=313, Percent_Identity=27.4760383386581, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=260, Percent_Identity=31.1538461538462, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45549126, Length=368, Percent_Identity=29.0760869565217, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24640980, Length=368, Percent_Identity=29.0760869565217, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646155, Length=238, Percent_Identity=30.2521008403361, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24646159, Length=183, Percent_Identity=28.9617486338798, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38721; Mature: 38721

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIKLGDSGVKVSQVAIGTWFLPRLQEKDELGIHKVDKETTLKILKRAYDEGVNFIDTA
CCEEEECCCCCEEEEEEEHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHCC
NRYHGAMAPVDLAHVGNAERIVGEFLKTVNRESVVISTKVRGKMGDFANGEGLSRKHIQW
HHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
QIKESLKRLGTSYIDLYFIHWPDPDTPKLETLRTLNSLVNNGLVYYLGVSNHSAIDVMEF
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
LHLSERYNLEKFVVMQEKYNMLERDIEKDKVDIARRYGLAVMAYSPLAQGFLTGKYTDRN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEEECCC
GWKVEELSRATISEDLKKRYFTDANLKILLGLKDIASELGITLSQLAIAWLLKRGEQLGV
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCE
TVIPLIGASKVEHLEDNLSALNVNLRDEHMKRIEEILGKST
EEEECCCCHHHHHHHCCHHHEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYIKLGDSGVKVSQVAIGTWFLPRLQEKDELGIHKVDKETTLKILKRAYDEGVNFIDTA
CCEEEECCCCCEEEEEEEHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHCC
NRYHGAMAPVDLAHVGNAERIVGEFLKTVNRESVVISTKVRGKMGDFANGEGLSRKHIQW
HHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
QIKESLKRLGTSYIDLYFIHWPDPDTPKLETLRTLNSLVNNGLVYYLGVSNHSAIDVMEF
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
LHLSERYNLEKFVVMQEKYNMLERDIEKDKVDIARRYGLAVMAYSPLAQGFLTGKYTDRN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEEECCC
GWKVEELSRATISEDLKKRYFTDANLKILLGLKDIASELGITLSQLAIAWLLKRGEQLGV
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCE
TVIPLIGASKVEHLEDNLSALNVNLRDEHMKRIEEILGKST
EEEECCCCHHHHHHHCCHHHEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]