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The map label for this gene is 227828549

Identifier: 227828549

GI number: 227828549

Start: 2105316

End: 2106803

Strand: Direct

Name: 227828549

Synonym: M1425_2300

Alternate gene names: NA

Gene position: 2105316-2106803 (Clockwise)

Preceding gene: 227828547

Following gene: 227828552

Centisome position: 80.7

GC content: 38.98

Gene sequence:

>1488_bases
ATGTCACAAAATTCTTACAAAATCTTGAAATCACTTCCAGTACCATCTAATGGTCCTTTCAAAGCTACCTGGAGTTCATT
AAAAAAGTATAGAGTCCCATCGTGGTTTACTACCTCTAAATTCGGTATTTTTATCCATTGGGGAGTATACTCAGTACCAG
CATTTGGTAATGAATGGTACCCTAGATACATGTACATGCCAGATAGACCAGAACACCAATATCACCTAAAAAACTTCGGC
CCAGTAACCGATTTCGGATATAAGGATTTCATACCGATGTTCACTGGAGAGAATTGGGATCCATATGAGTGGGCTAAGCT
CTTTAAGAAAAGTGGAGCTAAATTCGTAGTCCTAGTTGCAGAACATCACGATGGATTTGCACTATGGGAATCAAATTACA
CTAGGTGGTGTGCAACCAAGATTGGACCTAAAAGGGACATTGTTAGAGAACTTAAGGAAGCTGTTGAAGGTCAAGGGCTA
ATATTTGGCATTTCGTATCATAGGGCTGAGCACTGGTGGTTTTTCGATCAAGGGATGAAAATAGAGTCTGATGTAAAGGA
CCCCAGATATCTCGATTTATATGGCCCAGCTCAGTCTGCTTCCCTAAATCCTAGAGATCCACCTTCAAAGGATAATGTAC
AGCCAAATAATGAGTTTCTAATGGATTGGTTGCTTAGAATTGTTGAGGCTGTTGAAAAGTATAGGCCATGGCTAGTCTAT
TTCGACTGGTGGATTGCCAATCTCTCTTTCCAATCATACTTGAAAGCTTTTGCATCCTATTACTATAATAGGTCATACAA
ATGGGGAATAGAACCCGTAATAATTTACAAGCAAGGGGCATTTGAGGAAGGTACAGCCATACCGGATTTAGCTGAAAGGG
GAACAATAAAGAACGTATATCCCTCCACATGGTTAGCTGACACTTCTATAGACTACAAATCCTGGGGTTACATCAAAGAT
GCTGAATACAAGCTACCTAGTATTATATTATCCCATTTAGGTGATGTTGTTAGTAAAAATGGAGTTTTTCTCTTGAATAT
AGGACCTAAAGCTGACGGTACGATACCAGAAGAGGCTAAGAGAATTTTACTTGATGTTGGGGATTGGCTAAATGTAAATG
GCGAAGCGATTTTCGGATCAAAACCGTGGAGAGTTTACGGAGAAGGTCCTTCGGAAATTAATGAAGGGGGATTCTTTACA
GAGAGAAAAATTACTTTAGGCGATCAAGATGTGAGATACACTGTGAAAGACTATTATCCGCGACAGAGGCATATTTACGC
TATTGTCTTCGGAAAGCCTAAGGAAATTACGTTAAGGTCGTTTATGAAAAATCTAAAGCTAATAGAAGAAGGTGTAATAG
TAGATGTAAGCAGATTAGATGGGAAAGGTAAGTTAGAGTGGAGTTTAAGTGATGAAGGTTTAAAGATAAAAATAGAGGAA
GTTACAAGGGCTCCTCTTGTTATAAGGGTTATCCTAGATTATAGATAG

Upstream 100 bases:

>100_bases
CCCAAAACTGCTTTTCCCTGAAAGACATTATCAGCTAAATGTTAATCAACTTAAGAAAAGTTTAAGTGTACTTCCTCTAA
TCAATAGGTAGGTCAGTTAA

Downstream 100 bases:

>100_bases
GTAGCTCTACTTAGTAGTATATTATTGGGTTACAATTTACTATTGCTTAGATTTAATAGGTTTCAAATCTCTTTGCCAAG
ATACCTAGTGCATACTATAA

Product: alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Glycoside Hydrolase Family Alpha-L-Fucosidase; Fucosidase; Alpha-L-Fucosidase Protein; Family; Exporte Hydrolase; Exported Alpha-L-Fucosidase Protein; Alpha-L-Fucosidase Superfamily; Glycosyl Hydrolase Alpha-L-Fucosidase; Alpha-L-Fucosidase Family Protein; Glycoside Hydrolase

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSQNSYKILKSLPVPSNGPFKATWSSLKKYRVPSWFTTSKFGIFIHWGVYSVPAFGNEWYPRYMYMPDRPEHQYHLKNFG
PVTDFGYKDFIPMFTGENWDPYEWAKLFKKSGAKFVVLVAEHHDGFALWESNYTRWCATKIGPKRDIVRELKEAVEGQGL
IFGISYHRAEHWWFFDQGMKIESDVKDPRYLDLYGPAQSASLNPRDPPSKDNVQPNNEFLMDWLLRIVEAVEKYRPWLVY
FDWWIANLSFQSYLKAFASYYYNRSYKWGIEPVIIYKQGAFEEGTAIPDLAERGTIKNVYPSTWLADTSIDYKSWGYIKD
AEYKLPSIILSHLGDVVSKNGVFLLNIGPKADGTIPEEAKRILLDVGDWLNVNGEAIFGSKPWRVYGEGPSEINEGGFFT
ERKITLGDQDVRYTVKDYYPRQRHIYAIVFGKPKEITLRSFMKNLKLIEEGVIVDVSRLDGKGKLEWSLSDEGLKIKIEE
VTRAPLVIRVILDYR

Sequences:

>Translated_495_residues
MSQNSYKILKSLPVPSNGPFKATWSSLKKYRVPSWFTTSKFGIFIHWGVYSVPAFGNEWYPRYMYMPDRPEHQYHLKNFG
PVTDFGYKDFIPMFTGENWDPYEWAKLFKKSGAKFVVLVAEHHDGFALWESNYTRWCATKIGPKRDIVRELKEAVEGQGL
IFGISYHRAEHWWFFDQGMKIESDVKDPRYLDLYGPAQSASLNPRDPPSKDNVQPNNEFLMDWLLRIVEAVEKYRPWLVY
FDWWIANLSFQSYLKAFASYYYNRSYKWGIEPVIIYKQGAFEEGTAIPDLAERGTIKNVYPSTWLADTSIDYKSWGYIKD
AEYKLPSIILSHLGDVVSKNGVFLLNIGPKADGTIPEEAKRILLDVGDWLNVNGEAIFGSKPWRVYGEGPSEINEGGFFT
ERKITLGDQDVRYTVKDYYPRQRHIYAIVFGKPKEITLRSFMKNLKLIEEGVIVDVSRLDGKGKLEWSLSDEGLKIKIEE
VTRAPLVIRVILDYR
>Mature_494_residues
SQNSYKILKSLPVPSNGPFKATWSSLKKYRVPSWFTTSKFGIFIHWGVYSVPAFGNEWYPRYMYMPDRPEHQYHLKNFGP
VTDFGYKDFIPMFTGENWDPYEWAKLFKKSGAKFVVLVAEHHDGFALWESNYTRWCATKIGPKRDIVRELKEAVEGQGLI
FGISYHRAEHWWFFDQGMKIESDVKDPRYLDLYGPAQSASLNPRDPPSKDNVQPNNEFLMDWLLRIVEAVEKYRPWLVYF
DWWIANLSFQSYLKAFASYYYNRSYKWGIEPVIIYKQGAFEEGTAIPDLAERGTIKNVYPSTWLADTSIDYKSWGYIKDA
EYKLPSIILSHLGDVVSKNGVFLLNIGPKADGTIPEEAKRILLDVGDWLNVNGEAIFGSKPWRVYGEGPSEINEGGFFTE
RKITLGDQDVRYTVKDYYPRQRHIYAIVFGKPKEITLRSFMKNLKLIEEGVIVDVSRLDGKGKLEWSLSDEGLKIKIEEV
TRAPLVIRVILDYR

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=479, Percent_Identity=31.9415448851775, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI119360348, Length=472, Percent_Identity=30.9322033898305, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71997700, Length=433, Percent_Identity=29.3302540415704, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24662717, Length=401, Percent_Identity=31.9201995012469, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI78706642, Length=401, Percent_Identity=31.9201995012469, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 57546; Mature: 57415

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNSYKILKSLPVPSNGPFKATWSSLKKYRVPSWFTTSKFGIFIHWGVYSVPAFGNEWY
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCEECCCCCCCCC
PRYMYMPDRPEHQYHLKNFGPVTDFGYKDFIPMFTGENWDPYEWAKLFKKSGAKFVVLVA
CEEEECCCCCCCCEECCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
EHHDGFALWESNYTRWCATKIGPKRDIVRELKEAVEGQGLIFGISYHRAEHWWFFDQGMK
ECCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEECCCCE
IESDVKDPRYLDLYGPAQSASLNPRDPPSKDNVQPNNEFLMDWLLRIVEAVEKYRPWLVY
ECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE
FDWWIANLSFQSYLKAFASYYYNRSYKWGIEPVIIYKQGAFEEGTAIPDLAERGTIKNVY
EEEHHHCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCC
PSTWLADTSIDYKSWGYIKDAEYKLPSIILSHLGDVVSKNGVFLLNIGPKADGTIPEEAK
CCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
RILLDVGDWLNVNGEAIFGSKPWRVYGEGPSEINEGGFFTERKITLGDQDVRYTVKDYYP
HHEEECCCEECCCCCEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEHHHCCC
RQRHIYAIVFGKPKEITLRSFMKNLKLIEEGVIVDVSRLDGKGKLEWSLSDEGLKIKIEE
CCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEEEH
VTRAPLVIRVILDYR
HCCCCEEEEEEEECC
>Mature Secondary Structure 
SQNSYKILKSLPVPSNGPFKATWSSLKKYRVPSWFTTSKFGIFIHWGVYSVPAFGNEWY
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCEECCCCCCCCC
PRYMYMPDRPEHQYHLKNFGPVTDFGYKDFIPMFTGENWDPYEWAKLFKKSGAKFVVLVA
CEEEECCCCCCCCEECCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
EHHDGFALWESNYTRWCATKIGPKRDIVRELKEAVEGQGLIFGISYHRAEHWWFFDQGMK
ECCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEECCCCE
IESDVKDPRYLDLYGPAQSASLNPRDPPSKDNVQPNNEFLMDWLLRIVEAVEKYRPWLVY
ECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE
FDWWIANLSFQSYLKAFASYYYNRSYKWGIEPVIIYKQGAFEEGTAIPDLAERGTIKNVY
EEEHHHCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCC
PSTWLADTSIDYKSWGYIKDAEYKLPSIILSHLGDVVSKNGVFLLNIGPKADGTIPEEAK
CCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
RILLDVGDWLNVNGEAIFGSKPWRVYGEGPSEINEGGFFTERKITLGDQDVRYTVKDYYP
HHEEECCCEECCCCCEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEHHHCCC
RQRHIYAIVFGKPKEITLRSFMKNLKLIEEGVIVDVSRLDGKGKLEWSLSDEGLKIKIEE
CCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCEEEEEH
VTRAPLVIRVILDYR
HCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA