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The map label for this gene is ndh [H]

Identifier: 227828472

GI number: 227828472

Start: 2028178

End: 2029200

Strand: Direct

Name: ndh [H]

Synonym: M1425_2219

Alternate gene names: 227828472

Gene position: 2028178-2029200 (Clockwise)

Preceding gene: 227828470

Following gene: 227828473

Centisome position: 77.74

GC content: 37.05

Gene sequence:

>1023_bases
ATGCAAACTGAAAGAGTAGTAATATTAGGAGGAGGATTTGCTGGAATTGCAGCTAAGTTGGTATATCCTAATGCAATACT
CGTTGACGAAAAGGATTTCATGGTGGTTACTCCAAGGTTAGTAGAGGTTATAGAGAAAAACCTCCCTTTATCTCACGCTT
TAATTCCTAGGAAAGTTGACGTTAAGGCTAAGGTTTTAAAGATTGACTTTAAGGAGAAGAAAGTAATAACGAGTGATGGT
GAAATTAGGTTCGATAAGCTAATAATTGCGTTGGGTTATGAGCAAGATTTAAGTAAGATAAAAGGAGCTGAAAAGTACGG
TATAGGATTTACCTTGGAAAATGTAGAAAAGATCAAGTCATTTAAAGAAGGTTCGATAGTTACGATTCTTGGAGGAGGAG
CACTTGGGGTTGAGTTAGCTGGAGCGTTAAGGAAGAGGGGTTATACTGTAAATTTGGTTGAGGCAGAAAATAGATTAGTA
CCCTATCTGATACCAGATTTCTCTAATGAGGTTCAAAAGGTTTTGGAAAAGCAAGGCGTTAACGTAATTTTAAGGGCTAA
GGTAGAGGAAGTAAAGGAAAATGAGGTAATTACCACGCAAGGAAGAATAAGGAGTGATTATATAATATTCTCTGCGGGTT
TTTCCGGCCCCAAAATAATAAATGAAATCGGATTATCAAATAGGAACAATAGGATGTTAGTTTACAGATTCCTCAGATCA
GTAGATTATGATTTCGTTTATGGCGCTGGTGATTGCGCTAACTTTAAGGATGGGTTCATACCACAATCAGCACAAGTTTC
CTTACAGGCTGGTGAGGTTGCCATGAATAATGCAATAAAGGATGAGAAAGTTGAGTTTAAACCAGTACAGAAGGCTATAG
TATTTAAGATTGGTGAAGATTATATTGGTTTGCTAAAGCACACCGTAATAAGCGGCCCCATAGCGTCACTCATTAAATCC
TTTGCTATCAGTTCTTTAGAAGGTAAGGTTAAGAAACTGAATAAATTTATTCTAGCTATGTGA

Upstream 100 bases:

>100_bases
TAGGTACCATCATGTATTGAAACAAAACATACTAAAGAATGGCTCATTAGTTAAGAGATTAGCTGTAATATTTAAATAGC
GATGTGTAAAGTATAAACAT

Downstream 100 bases:

>100_bases
ACTGACTTATCCTTTAACCTATCCTAGTTTTCTATTTTAACGTGATCTTGGAGCATTAAGTTTTCTAAATAAAAAATTGG
GAATTGTACACAGTTAAATA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQTERVVILGGGFAGIAAKLVYPNAILVDEKDFMVVTPRLVEVIEKNLPLSHALIPRKVDVKAKVLKIDFKEKKVITSDG
EIRFDKLIIALGYEQDLSKIKGAEKYGIGFTLENVEKIKSFKEGSIVTILGGGALGVELAGALRKRGYTVNLVEAENRLV
PYLIPDFSNEVQKVLEKQGVNVILRAKVEEVKENEVITTQGRIRSDYIIFSAGFSGPKIINEIGLSNRNNRMLVYRFLRS
VDYDFVYGAGDCANFKDGFIPQSAQVSLQAGEVAMNNAIKDEKVEFKPVQKAIVFKIGEDYIGLLKHTVISGPIASLIKS
FAISSLEGKVKKLNKFILAM

Sequences:

>Translated_340_residues
MQTERVVILGGGFAGIAAKLVYPNAILVDEKDFMVVTPRLVEVIEKNLPLSHALIPRKVDVKAKVLKIDFKEKKVITSDG
EIRFDKLIIALGYEQDLSKIKGAEKYGIGFTLENVEKIKSFKEGSIVTILGGGALGVELAGALRKRGYTVNLVEAENRLV
PYLIPDFSNEVQKVLEKQGVNVILRAKVEEVKENEVITTQGRIRSDYIIFSAGFSGPKIINEIGLSNRNNRMLVYRFLRS
VDYDFVYGAGDCANFKDGFIPQSAQVSLQAGEVAMNNAIKDEKVEFKPVQKAIVFKIGEDYIGLLKHTVISGPIASLIKS
FAISSLEGKVKKLNKFILAM
>Mature_340_residues
MQTERVVILGGGFAGIAAKLVYPNAILVDEKDFMVVTPRLVEVIEKNLPLSHALIPRKVDVKAKVLKIDFKEKKVITSDG
EIRFDKLIIALGYEQDLSKIKGAEKYGIGFTLENVEKIKSFKEGSIVTILGGGALGVELAGALRKRGYTVNLVEAENRLV
PYLIPDFSNEVQKVLEKQGVNVILRAKVEEVKENEVITTQGRIRSDYIIFSAGFSGPKIINEIGLSNRNNRMLVYRFLRS
VDYDFVYGAGDCANFKDGFIPQSAQVSLQAGEVAMNNAIKDEKVEFKPVQKAIVFKIGEDYIGLLKHTVISGPIASLIKS
FAISSLEGKVKKLNKFILAM

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789065, Length=230, Percent_Identity=24.3478260869565, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 37554; Mature: 37554

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTERVVILGGGFAGIAAKLVYPNAILVDEKDFMVVTPRLVEVIEKNLPLSHALIPRKVD
CCCCEEEEECCCHHHHHHHEECCCEEEEECCCCEEECHHHHHHHHHCCCCCCCCCCCEEC
VKAKVLKIDFKEKKVITSDGEIRFDKLIIALGYEQDLSKIKGAEKYGIGFTLENVEKIKS
CEEEEEEEECCCCEEEECCCCEEEEEEEEEECCHHHHHHHCCCCCCCCCEEHHHHHHHHH
FKEGSIVTILGGGALGVELAGALRKRGYTVNLVEAENRLVPYLIPDFSNEVQKVLEKQGV
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCC
NVILRAKVEEVKENEVITTQGRIRSDYIIFSAGFSGPKIINEIGLSNRNNRMLVYRFLRS
CEEEEEEHHHHCCCCEEEECCCEECCEEEEECCCCCCHHHHHHCCCCCCCCCHHEEHHHH
VDYDFVYGAGDCANFKDGFIPQSAQVSLQAGEVAMNNAIKDEKVEFKPVQKAIVFKIGED
CCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHCCCCCCCCCHHHHHCEEEEEEECHH
YIGLLKHTVISGPIASLIKSFAISSLEGKVKKLNKFILAM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTERVVILGGGFAGIAAKLVYPNAILVDEKDFMVVTPRLVEVIEKNLPLSHALIPRKVD
CCCCEEEEECCCHHHHHHHEECCCEEEEECCCCEEECHHHHHHHHHCCCCCCCCCCCEEC
VKAKVLKIDFKEKKVITSDGEIRFDKLIIALGYEQDLSKIKGAEKYGIGFTLENVEKIKS
CEEEEEEEECCCCEEEECCCCEEEEEEEEEECCHHHHHHHCCCCCCCCCEEHHHHHHHHH
FKEGSIVTILGGGALGVELAGALRKRGYTVNLVEAENRLVPYLIPDFSNEVQKVLEKQGV
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCC
NVILRAKVEEVKENEVITTQGRIRSDYIIFSAGFSGPKIINEIGLSNRNNRMLVYRFLRS
CEEEEEEHHHHCCCCEEEECCCEECCEEEEECCCCCCHHHHHHCCCCCCCCCHHEEHHHH
VDYDFVYGAGDCANFKDGFIPQSAQVSLQAGEVAMNNAIKDEKVEFKPVQKAIVFKIGED
CCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHCCCCCCCCCHHHHHCEEEEEEECHH
YIGLLKHTVISGPIASLIKSFAISSLEGKVKKLNKFILAM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]