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The map label for this gene is queC [H]

Identifier: 227828356

GI number: 227828356

Start: 1921380

End: 1922774

Strand: Direct

Name: queC [H]

Synonym: M1425_2098

Alternate gene names: 227828356

Gene position: 1921380-1922774 (Clockwise)

Preceding gene: 227828355

Following gene: 227828357

Centisome position: 73.65

GC content: 37.35

Gene sequence:

>1395_bases
GTGTGTAGTGTATCTGGAGTCCTTATATTAAACCCTAAAAATTTTGACAAAGTTGAGCGAAAATTAGCTGATATTCTCAA
AAGGGCAGAGGATAGGGGTAGGGATAGTTTTGGAATTGTTGTAATTCAAAAGGACGGTACGGTGAAAGTGAGAAAATCCA
TAGGGAAGCCTTCAGAAAAAGAGGAATTGCTGTATGGAATTTTAGATGAAGACTCTAGAGTAGTAATAGCTAATAATAGG
GCAGAGCCTACGACTGAATATGTTAGACAGAAGACTGAAGAGGATATTCAACCCTTTATCGGAGATAGATATATTGTAAC
CCATAATGGAATAATAGCGAATGATTTAGAATTAGAGAAAAAATACGAGCTTAAAAGAAAGACTAAGATCGATAGTGCAA
TTCTTCCATCACTTTTAGATAAAACATGGGATGGTAATCTTGGAACATTAAAGGGAATTTTAGAACAAATTAGAGGAAGC
TTTGCTTTAGTTATAGGTGATAAGAGAAATCATGATAGAATATTTCTAGCTCAGAACTTTAAGCCATTATACATGGCTTA
TGACTACTCGTTGGAGTCAATATTCTTTACGTCTCTTGATGAGTATTTTGACGTAAAACCATTTGACCTAGTAAACGTAA
CTAAACTAGAACCTTATTCTGTAGTAATGGTGAGTTCAAATAAGCAAATAACTACGTTACCGATCATAGAGAAAAGAAAA
AAACATAAGGTACTTGTCGTGGCAAGTGGTGGGCTAGATTCAACTGTTGCGGCTACTAAACTTTTAAGGGAAGGTCATGA
AGTTACCCTAATACACTTTAATTACCATCATAAAGCTGAGGAAAGAGAAAGAGAGGCAGTGAGGAAGATTGCTGAGCATT
TGCAAGTTCCTCTAATTGAAATAAATACAGATTTATTTAAAATGATAGGTCACGCTACGCTAATAAAGGGAGGGGGAGAA
ATAGTTAAGGATAGGAAAGGAGAAGAAGGGGCAGAGTTTGCGCACGAATGGGTTCCTGCAAGAAACCTAATTTTCTTTTC
AGCGGCATTAGCAATTGCCGAAGCTTATGGATACGACGCAATAGCCTCTGGGATAAATTTAGAGGAAGCTGGAGCTTATC
CAGATAACGAGATGGAGTTCATAAGGATGTTAAGTAAGTTAAGCCCCTATGCGACTGGCCCAAATAAGAAAGTGGAGGTA
TTGATGCCAGTTGGTAATTTAGTGAAGCATGAAATAGTAAAGCTGGGATACGAAATTGGTGCTCCATTACATTTAACATG
GAGCTGTTATGAAGGAGGGCAAAAACATTGTGGAAAATGTGGACCTTGTTATATGAGGAGGGTGGCGTTTAAGATTAATG
GACTTAGAGATCCAGTTGAGTATGCTGAAGAATGA

Upstream 100 bases:

>100_bases
GGATTCTCCATGATTGATGGTGAAAATTTAGAAGGAGATCTAATTATGATAAAATTAGAGTTTAGACAGATTTTTAGGTA
AGCTATAAAGGTATAAACAA

Downstream 100 bases:

>100_bases
TCGAATACTTTAATAACCATTTGGATAGTACTATTTTTTATGCTATCTCCAATAGAATTTTTTGTTATAGTTGTGCTAAT
TAGTGCTCTTTCAGGTATAC

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MCSVSGVLILNPKNFDKVERKLADILKRAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEEDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPSLLDKTWDGNLGTLKGILEQIRGS
FALVIGDKRNHDRIFLAQNFKPLYMAYDYSLESIFFTSLDEYFDVKPFDLVNVTKLEPYSVVMVSSNKQITTLPIIEKRK
KHKVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEREREAVRKIAEHLQVPLIEINTDLFKMIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSAALAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLSKLSPYATGPNKKVEV
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRRVAFKINGLRDPVEYAEE

Sequences:

>Translated_464_residues
MCSVSGVLILNPKNFDKVERKLADILKRAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEEDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPSLLDKTWDGNLGTLKGILEQIRGS
FALVIGDKRNHDRIFLAQNFKPLYMAYDYSLESIFFTSLDEYFDVKPFDLVNVTKLEPYSVVMVSSNKQITTLPIIEKRK
KHKVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEREREAVRKIAEHLQVPLIEINTDLFKMIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSAALAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLSKLSPYATGPNKKVEV
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRRVAFKINGLRDPVEYAEE
>Mature_464_residues
MCSVSGVLILNPKNFDKVERKLADILKRAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEEDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPSLLDKTWDGNLGTLKGILEQIRGS
FALVIGDKRNHDRIFLAQNFKPLYMAYDYSLESIFFTSLDEYFDVKPFDLVNVTKLEPYSVVMVSSNKQITTLPIIEKRK
KHKVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEREREAVRKIAEHLQVPLIEINTDLFKMIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSAALAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLSKLSPYATGPNKKVEV
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRRVAFKINGLRDPVEYAEE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017932
- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 52326; Mature: 52326

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSVSGVLILNPKNFDKVERKLADILKRAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEK
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCH
EELLYGILDEDSRVVIANNRAEPTTEYVRQKTEEDIQPFIGDRYIVTHNGIIANDLELEK
HHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHH
KYELKRKTKIDSAILPSLLDKTWDGNLGTLKGILEQIRGSFALVIGDKRNHDRIFLAQNF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCC
KPLYMAYDYSLESIFFTSLDEYFDVKPFDLVNVTKLEPYSVVMVSSNKQITTLPIIEKRK
CEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCEEEEECHHHCCC
KHKVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEREREAVRKIAEHLQVPLIE
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEE
INTDLFKMIGHATLIKGGGEIVKDRKGEEGAEFAHEWVPARNLIFFSAALAIAEAYGYDA
ECHHHHHHHCCCEEECCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
IASGINLEEAGAYPDNEMEFIRMLSKLSPYATGPNKKVEVLMPVGNLVKHEIVKLGYEIG
HHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC
APLHLTWSCYEGGQKHCGKCGPCYMRRVAFKINGLRDPVEYAEE
CCEEEEEEHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MCSVSGVLILNPKNFDKVERKLADILKRAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEK
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCH
EELLYGILDEDSRVVIANNRAEPTTEYVRQKTEEDIQPFIGDRYIVTHNGIIANDLELEK
HHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHH
KYELKRKTKIDSAILPSLLDKTWDGNLGTLKGILEQIRGSFALVIGDKRNHDRIFLAQNF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCC
KPLYMAYDYSLESIFFTSLDEYFDVKPFDLVNVTKLEPYSVVMVSSNKQITTLPIIEKRK
CEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCEEEEECHHHCCC
KHKVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEREREAVRKIAEHLQVPLIE
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEE
INTDLFKMIGHATLIKGGGEIVKDRKGEEGAEFAHEWVPARNLIFFSAALAIAEAYGYDA
ECHHHHHHHCCCEEECCCCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
IASGINLEEAGAYPDNEMEFIRMLSKLSPYATGPNKKVEVLMPVGNLVKHEIVKLGYEIG
HHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC
APLHLTWSCYEGGQKHCGKCGPCYMRRVAFKINGLRDPVEYAEE
CCEEEEEEHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]