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The map label for this gene is yebU [C]

Identifier: 227828150

GI number: 227828150

Start: 1728664

End: 1729683

Strand: Direct

Name: yebU [C]

Synonym: M1425_1888

Alternate gene names: 227828150

Gene position: 1728664-1729683 (Clockwise)

Preceding gene: 227828146

Following gene: 227828151

Centisome position: 66.26

GC content: 33.82

Gene sequence:

>1020_bases
ATGGAAAATCGTATAGCGAGGTATTTAAGTGAAAATGCCAATTTGTTTCATATTTCTCCTAGTTATAAGGCTAAAAGATT
AGCCTCTAAGTATGGATTTTTAGATTATATGATAGAACGATATTTGAATATGTTTAGTAGTAAAGAAGAATTAGAAGAAT
ATCTAAATTCTTGTAGTTTTCCATTAAAAAAGAGTATTAGATGTAATACGTTGAGAACTGACTGCAAAAAATTGGAAGAA
ATGATGTCAGAGAAAGGATTCATTTTGGAAAAGGTCAAATGGCTTCAGCATGGTTATATAATTAAAAGAACTCCACCTAA
GCCGTCTCTAGGTTCTACACTTGAGTATCTCATGGGATATTATCATATTCAAGGGCTAGCTTCTATGGTACCCGCGTATG
TCCTAAATCCTTCACAAGATGATTTTGTTTTGGATATGGCTGCGGCACCTGGTGGAAAAACTACACAAGTATCTCAAATA
ATGCAGAATAAAGGTTTGGTAGTAGCAGTTGAGAAAAAGCGTAGTAGGATTAGAGCTCTTCTCAGTAATGTTAATAGGTT
AGGGGCAGAGAATGTTGTACTAGTCAAAACCGATGTATTAAATTTAAGAAGAATAAATAAATTTCAATTCGATAGAATCT
TATTAGACGCACCTTGTAGCGGTGAAGGATTAATACAAAAGGATCCTACTAGGCGATATAAAACCACAATTGATGACTTA
AGGGATTTTGCATATTCACAGCTATCTCTAATCGAGATAGCATATGAGCTATTGAAAGAGGGCGGTTATATCGTTTATTC
AACATGTAGCGTTGCACCAGAAGAGAATGAATTAATTGTTAATTTCGCTATCGAAGAATTAGGTATGAAAACCATGAGTG
TAGAAGGATATCCTGCTTCTAACGGATACGTAGAATATTATAATACTAGATTTAATATCGATGTGAAGAATTGTTTAAGA
TTTTTCCCTCATACACAAGGTACTGAGGGGTTTTTCCTATGCCTTTTAAAGAAGGAATAA

Upstream 100 bases:

>100_bases
TATCCAATAATTTTAGTTCTTTCTCCAACGATTCTCTTAACTCGTCTAATGATGGGTACTCAACTACTATTTTAACCTCT
TTTTCGATCATTATTCTCTG

Downstream 100 bases:

>100_bases
AGATGAGTTTTAGTAAGGTTGGAATAGATGAAGTTAAACCCAAACTTGAGGTTATTTTCTCAAGATATGGTTGTGTAAAT
AAGTTAAGTACATTTATAAC

Product: RNA methylase, NOL1/NOP2/sun family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MENRIARYLSENANLFHISPSYKAKRLASKYGFLDYMIERYLNMFSSKEELEEYLNSCSFPLKKSIRCNTLRTDCKKLEE
MMSEKGFILEKVKWLQHGYIIKRTPPKPSLGSTLEYLMGYYHIQGLASMVPAYVLNPSQDDFVLDMAAAPGGKTTQVSQI
MQNKGLVVAVEKKRSRIRALLSNVNRLGAENVVLVKTDVLNLRRINKFQFDRILLDAPCSGEGLIQKDPTRRYKTTIDDL
RDFAYSQLSLIEIAYELLKEGGYIVYSTCSVAPEENELIVNFAIEELGMKTMSVEGYPASNGYVEYYNTRFNIDVKNCLR
FFPHTQGTEGFFLCLLKKE

Sequences:

>Translated_339_residues
MENRIARYLSENANLFHISPSYKAKRLASKYGFLDYMIERYLNMFSSKEELEEYLNSCSFPLKKSIRCNTLRTDCKKLEE
MMSEKGFILEKVKWLQHGYIIKRTPPKPSLGSTLEYLMGYYHIQGLASMVPAYVLNPSQDDFVLDMAAAPGGKTTQVSQI
MQNKGLVVAVEKKRSRIRALLSNVNRLGAENVVLVKTDVLNLRRINKFQFDRILLDAPCSGEGLIQKDPTRRYKTTIDDL
RDFAYSQLSLIEIAYELLKEGGYIVYSTCSVAPEENELIVNFAIEELGMKTMSVEGYPASNGYVEYYNTRFNIDVKNCLR
FFPHTQGTEGFFLCLLKKE
>Mature_339_residues
MENRIARYLSENANLFHISPSYKAKRLASKYGFLDYMIERYLNMFSSKEELEEYLNSCSFPLKKSIRCNTLRTDCKKLEE
MMSEKGFILEKVKWLQHGYIIKRTPPKPSLGSTLEYLMGYYHIQGLASMVPAYVLNPSQDDFVLDMAAAPGGKTTQVSQI
MQNKGLVVAVEKKRSRIRALLSNVNRLGAENVVLVKTDVLNLRRINKFQFDRILLDAPCSGEGLIQKDPTRRYKTTIDDL
RDFAYSQLSLIEIAYELLKEGGYIVYSTCSVAPEENELIVNFAIEELGMKTMSVEGYPASNGYVEYYNTRFNIDVKNCLR
FFPHTQGTEGFFLCLLKKE

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=321, Percent_Identity=33.6448598130841, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI76150623, Length=321, Percent_Identity=33.6448598130841, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI32698918, Length=202, Percent_Identity=32.6732673267327, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI39995082, Length=273, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI301336155, Length=273, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI270288818, Length=295, Percent_Identity=24.7457627118644, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI8922322, Length=295, Percent_Identity=24.7457627118644, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI270288816, Length=295, Percent_Identity=24.7457627118644, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI23199998, Length=295, Percent_Identity=24.7457627118644, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI11545785, Length=204, Percent_Identity=28.921568627451, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40316918, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87081985, Length=316, Percent_Identity=33.5443037974684, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI2367212, Length=184, Percent_Identity=32.6086956521739, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=319, Percent_Identity=35.1097178683386, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25143471, Length=280, Percent_Identity=27.5, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17509941, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=323, Percent_Identity=34.6749226006192, Blast_Score=195, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6319447, Length=364, Percent_Identity=26.3736263736264, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324306, Length=273, Percent_Identity=24.9084249084249, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI22024126, Length=315, Percent_Identity=35.2380952380952, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21355201, Length=296, Percent_Identity=27.7027027027027, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668781, Length=179, Percent_Identity=32.9608938547486, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356513, Length=179, Percent_Identity=32.9608938547486, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21356579, Length=217, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19920494, Length=191, Percent_Identity=28.2722513089005, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 38914; Mature: 38914

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRIARYLSENANLFHISPSYKAKRLASKYGFLDYMIERYLNMFSSKEELEEYLNSCSF
CCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PLKKSIRCNTLRTDCKKLEEMMSEKGFILEKVKWLQHGYIIKRTPPKPSLGSTLEYLMGY
CHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
YHIQGLASMVPAYVLNPSQDDFVLDMAAAPGGKTTQVSQIMQNKGLVVAVEKKRSRIRAL
HHHHHHHHHCHHEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHH
LSNVNRLGAENVVLVKTDVLNLRRINKFQFDRILLDAPCSGEGLIQKDPTRRYKTTIDDL
HHHHHHCCCCCEEEEEECHHHHHHHCHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
RDFAYSQLSLIEIAYELLKEGGYIVYSTCSVAPEENELIVNFAIEELGMKTMSVEGYPAS
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEHHHHCCEEEEECCCCCC
NGYVEYYNTRFNIDVKNCLRFFPHTQGTEGFFLCLLKKE
CCEEEEECCEEEEEHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MENRIARYLSENANLFHISPSYKAKRLASKYGFLDYMIERYLNMFSSKEELEEYLNSCSF
CCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PLKKSIRCNTLRTDCKKLEEMMSEKGFILEKVKWLQHGYIIKRTPPKPSLGSTLEYLMGY
CHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
YHIQGLASMVPAYVLNPSQDDFVLDMAAAPGGKTTQVSQIMQNKGLVVAVEKKRSRIRAL
HHHHHHHHHCHHEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHH
LSNVNRLGAENVVLVKTDVLNLRRINKFQFDRILLDAPCSGEGLIQKDPTRRYKTTIDDL
HHHHHHCCCCCEEEEEECHHHHHHHCHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHH
RDFAYSQLSLIEIAYELLKEGGYIVYSTCSVAPEENELIVNFAIEELGMKTMSVEGYPAS
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEHHHHCCEEEEECCCCCC
NGYVEYYNTRFNIDVKNCLRFFPHTQGTEGFFLCLLKKE
CCEEEEECCEEEEEHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]