Click here to switch to the map view.

The map label for this gene is 227828141

Identifier: 227828141

GI number: 227828141

Start: 1721539

End: 1722306

Strand: Direct

Name: 227828141

Synonym: M1425_1879

Alternate gene names: NA

Gene position: 1721539-1722306 (Clockwise)

Preceding gene: 227828140

Following gene: 227828142

Centisome position: 65.99

GC content: 34.11

Gene sequence:

>768_bases
ATGAAAATACGGAAGAAGAAAATGAAATTGAAGGGGAAAGTGAAGAAATACCTCATGGACAAGTTAAATGATAATGAGAA
ATTACATTTTTCTCTCCTAGACCCATTTAAAATTAATTCTAGTGAAGAACTTAAATATATTGCTAAGAACTTATATAACG
TTGGAACCGATGCGTTTCTTATTGGAGGCACATTAGGTGTTTCTAAAGATAAATTAGATTTTGTCATATCCTTACTTGAC
GATTATGAAATACCGAAGATTATATTCCCTAGCAATATAAACCTTTTATCTGAGAAGGCTGATGCATTATTATTTTTATC
CCTATTAAACTCTGACGATATATATTATGTGATAGGTGCGCAAATAGTAGCTGCTCCAATCATAAAAATGTTACAAATAG
AGGTAATACCAACTGCTTATGTAATAGTAGGACATGGAGGTACTGCAGCACACATAGGCAAGGCCAGAGTAATACCCTAT
GATAATTTTGAGTTAGCAACTGCCTATACTTTAGCCGCGGAGTATTTAGGAATGGATTTTGTTTACCTCGAGGCCGGATC
TGGAGCCCCAGAACCAATAAGGCCAGAAATGATATCTTTTATCAAAAAGGCTTCCAGTATCCCGTTAATTATAGGAGGTG
GAATAAGAAGCGTGGAAGTCGCTTTAAAATTAGTTGAAGCTGGAGCAAATATAATTGTTACTGGAAATATAATTGAAAGA
GACGTCGATAAGGCAATAAAAATAATAAGGGGAATAAAGAATAAATAA

Upstream 100 bases:

>100_bases
ACTGAAATTGAAGTACCCTCTGTATTTGATGAGGCAAATGCTTATTCCAAATTCATAGACATGTACTTGGAGGGAAGATT
ACAAATAAAAGAGAGAACTA

Downstream 100 bases:

>100_bases
CCAAGGAAGAGGGGTTTATAATGCCTTCATCAAAGAAGAAAAAAGAGACTGTCCCAGTAATGTCAATGGCAGGATTAATT
AGATATTATGAGGAGGAAAA

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFLIGGTLGVSKDKLDFVISLLD
DYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGAQIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPY
DNFELATAYTLAAEYLGMDFVYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIER
DVDKAIKIIRGIKNK

Sequences:

>Translated_255_residues
MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFLIGGTLGVSKDKLDFVISLLD
DYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGAQIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPY
DNFELATAYTLAAEYLGMDFVYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIER
DVDKAIKIIRGIKNK
>Mature_255_residues
MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFLIGGTLGVSKDKLDFVISLLD
DYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGAQIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPY
DNFELATAYTLAAEYLGMDFVYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIER
DVDKAIKIIRGIKNK

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008205
- InterPro:   IPR010946 [H]

Pfam domain/function: PF01884 PcrB [H]

EC number: =2.5.1.41 [H]

Molecular weight: Translated: 28042; Mature: 28042

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFL
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCCEEE
IGGTLGVSKDKLDFVISLLDDYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGA
EECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHEEEEEHHCCCCEEEEECH
QIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPYDNFELATAYTLAAEYLGMDF
HHHHHHHHHHHEEEEECEEEEEEECCCCEEECCCEEEECCCCCHHHHHHHHHHHHHCCEE
VYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIER
EEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEECCHHHH
DVDKAIKIIRGIKNK
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFL
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCCEEE
IGGTLGVSKDKLDFVISLLDDYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGA
EECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHEEEEEHHCCCCEEEEECH
QIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPYDNFELATAYTLAAEYLGMDF
HHHHHHHHHHHEEEEECEEEEEEECCCCEEECCCEEEECCCCCHHHHHHHHHHHHHCCEE
VYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIER
EEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEECCHHHH
DVDKAIKIIRGIKNK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA