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The map label for this gene is yaaU [H]

Identifier: 227828075

GI number: 227828075

Start: 1677574

End: 1678929

Strand: Direct

Name: yaaU [H]

Synonym: M1425_1812

Alternate gene names: 227828075

Gene position: 1677574-1678929 (Clockwise)

Preceding gene: 227828074

Following gene: 227828076

Centisome position: 64.3

GC content: 35.55

Gene sequence:

>1356_bases
ATGGACTATAATAAAACGAATTTTTCCACATTAGAATTCAAGAGCGTCTTGACAGCGGGTATGGGAGTATTTACTGATGG
GTATGAACTTTACGCGATCTCTTTAGTTTTCTATTATATACAAAAGGAATTTTTATTAAATGGGCTTGAGGAAGGAATAG
TTATAGCTAGTGCGTATTATGGTGCAGCAGTTTCTGCAATTCTATTAGGCTTTTTATCAGATAAACTAGGAAGAAAGTTC
ATCTATGGTCTCGATGTAGCTTTAATGAGTCTAGGAATACTATTTCAGTCGATATCAACGAATTTTACAGAGTTAGTTAT
GTCTAGAATAATCTTAGGTTTTGGAATTGGAGCAGATTATGTTCTTTCTCCTATAATTACTGCAGAGAATTCAAATCCCA
AAAATAGAGGAAAACGAATGATAATAACATTTGCAGTACTTTGGGGAATGGGTGCAGTTGCCGCAGCATTTATCGAACAA
ATCTTGCTGTTAATTAACATAGGGAATGATCTCATATGGAGAATAGTATTGTTTATGGGAATCCTCCCAGCAGTTTCTGT
ATTTTACCTAAGGAGAAAACTCCCTGAAACATATAAATTCTTGACTAGAATTAAACCAAAGCGAGAAGAATTAAAGAAGT
TGGAAAACGAAATAAAAAGTAAAATTACAATTTCTTTAGATGAAGTTCCATTCTCAAAAAGATTCATATCAGCTATAGGA
ATTACAATTATATCTTCTATACTCTGGCTTCTTTACGATATGTATTCCTCTACGTTTGCGATCTACGGGCCAATAACCAT
AGCGGGAAACTTAGGCCTAAATCCCATAGAATTCACATATTTGGCACAGTTTCTTGCAGGTTTACCGGGTCAGATAATAA
GCATTTATCTAGTGGACAAAATAGGAAGAAAACCATTAATTGTGATAGGTTATGCTGGTGTTGCGTTTTGGCTTTTCATG
TATACAATGCTTCTCATGAATCCGTATTACTTTGGACTTAGCATACATATAAGTAATCCGTTAAAAGCAGCAGAAAGTTT
AACCGGAGAGGCGGCATTGTTGGGTCTATTATTTTATCTTATGAACTATTTATCATCAGCAATTGGACCCGCATCTATAA
TAGGGTCAGCAATGCTAACTTCAGAGTTAGTTCCAACAAAAGTTAGGGGGACCAGCCAAGCTATTAGTGTGGCAGCAGAT
AGACTAGCCGCAGCTTTTAGTATTACAGCATTTCCTCTGCTATTAGCCAAATTTGGACTCCCTGCATTACTAGCAGTATA
CTCAACAATTGCACTAGTATCATGTATTATAACTCTACTTTTAATACCAGAAACCAAAGGAGTAGAGTTAAGTTGA

Upstream 100 bases:

>100_bases
GGTCCCGGGTTCAAATCCCGGCGGGTCCGCACATATTATCACTTGGTATATACTAATTCTAGATACTCTTATAATCTCAA
CAAAATACATACAACACGAA

Downstream 100 bases:

>100_bases
AATAGTTTTTACTTAATATTTTATTTTTAGTCACAATATATAAAGATTTTAATAAAAACTGTGATAAGCTTAGCTATTTA
TGGTATAATGGGCAATCGTG

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MDYNKTNFSTLEFKSVLTAGMGVFTDGYELYAISLVFYYIQKEFLLNGLEEGIVIASAYYGAAVSAILLGFLSDKLGRKF
IYGLDVALMSLGILFQSISTNFTELVMSRIILGFGIGADYVLSPIITAENSNPKNRGKRMIITFAVLWGMGAVAAAFIEQ
ILLLINIGNDLIWRIVLFMGILPAVSVFYLRRKLPETYKFLTRIKPKREELKKLENEIKSKITISLDEVPFSKRFISAIG
ITIISSILWLLYDMYSSTFAIYGPITIAGNLGLNPIEFTYLAQFLAGLPGQIISIYLVDKIGRKPLIVIGYAGVAFWLFM
YTMLLMNPYYFGLSIHISNPLKAAESLTGEAALLGLLFYLMNYLSSAIGPASIIGSAMLTSELVPTKVRGTSQAISVAAD
RLAAAFSITAFPLLLAKFGLPALLAVYSTIALVSCIITLLLIPETKGVELS

Sequences:

>Translated_451_residues
MDYNKTNFSTLEFKSVLTAGMGVFTDGYELYAISLVFYYIQKEFLLNGLEEGIVIASAYYGAAVSAILLGFLSDKLGRKF
IYGLDVALMSLGILFQSISTNFTELVMSRIILGFGIGADYVLSPIITAENSNPKNRGKRMIITFAVLWGMGAVAAAFIEQ
ILLLINIGNDLIWRIVLFMGILPAVSVFYLRRKLPETYKFLTRIKPKREELKKLENEIKSKITISLDEVPFSKRFISAIG
ITIISSILWLLYDMYSSTFAIYGPITIAGNLGLNPIEFTYLAQFLAGLPGQIISIYLVDKIGRKPLIVIGYAGVAFWLFM
YTMLLMNPYYFGLSIHISNPLKAAESLTGEAALLGLLFYLMNYLSSAIGPASIIGSAMLTSELVPTKVRGTSQAISVAAD
RLAAAFSITAFPLLLAKFGLPALLAVYSTIALVSCIITLLLIPETKGVELS
>Mature_451_residues
MDYNKTNFSTLEFKSVLTAGMGVFTDGYELYAISLVFYYIQKEFLLNGLEEGIVIASAYYGAAVSAILLGFLSDKLGRKF
IYGLDVALMSLGILFQSISTNFTELVMSRIILGFGIGADYVLSPIITAENSNPKNRGKRMIITFAVLWGMGAVAAAFIEQ
ILLLINIGNDLIWRIVLFMGILPAVSVFYLRRKLPETYKFLTRIKPKREELKKLENEIKSKITISLDEVPFSKRFISAIG
ITIISSILWLLYDMYSSTFAIYGPITIAGNLGLNPIEFTYLAQFLAGLPGQIISIYLVDKIGRKPLIVIGYAGVAFWLFM
YTMLLMNPYYFGLSIHISNPLKAAESLTGEAALLGLLFYLMNYLSSAIGPASIIGSAMLTSELVPTKVRGTSQAISVAAD
RLAAAFSITAFPLLLAKFGLPALLAVYSTIALVSCIITLLLIPETKGVELS

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI203098995, Length=332, Percent_Identity=23.1927710843373, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786229, Length=468, Percent_Identity=23.9316239316239, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790463, Length=442, Percent_Identity=27.6018099547511, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789312, Length=447, Percent_Identity=24.6085011185682, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082159, Length=440, Percent_Identity=25.6818181818182, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789207, Length=449, Percent_Identity=23.8307349665924, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082231, Length=204, Percent_Identity=24.0196078431373, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082404, Length=387, Percent_Identity=24.5478036175711, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323512, Length=530, Percent_Identity=26.0377358490566, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324469, Length=461, Percent_Identity=22.3427331887202, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319941, Length=451, Percent_Identity=22.6164079822616, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320766, Length=442, Percent_Identity=22.1719457013575, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324400, Length=442, Percent_Identity=22.1719457013575, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320705, Length=475, Percent_Identity=22.3157894736842, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49483; Mature: 49483

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYNKTNFSTLEFKSVLTAGMGVFTDGYELYAISLVFYYIQKEFLLNGLEEGIVIASAYY
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHH
GAAVSAILLGFLSDKLGRKFIYGLDVALMSLGILFQSISTNFTELVMSRIILGFGIGADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
VLSPIITAENSNPKNRGKRMIITFAVLWGMGAVAAAFIEQILLLINIGNDLIWRIVLFMG
HHCCCEECCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILPAVSVFYLRRKLPETYKFLTRIKPKREELKKLENEIKSKITISLDEVPFSKRFISAIG
HHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHH
ITIISSILWLLYDMYSSTFAIYGPITIAGNLGLNPIEFTYLAQFLAGLPGQIISIYLVDK
HHHHHHHHHHHHHHHHCCEEEEECEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IGRKPLIVIGYAGVAFWLFMYTMLLMNPYYFGLSIHISNPLKAAESLTGEAALLGLLFYL
CCCCCEEEEEHHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHHHHHCCCHHHHHHHHHHH
MNYLSSAIGPASIIGSAMLTSELVPTKVRGTSQAISVAADRLAAAFSITAFPLLLAKFGL
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
PALLAVYSTIALVSCIITLLLIPETKGVELS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDYNKTNFSTLEFKSVLTAGMGVFTDGYELYAISLVFYYIQKEFLLNGLEEGIVIASAYY
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCEEEEHHHH
GAAVSAILLGFLSDKLGRKFIYGLDVALMSLGILFQSISTNFTELVMSRIILGFGIGADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
VLSPIITAENSNPKNRGKRMIITFAVLWGMGAVAAAFIEQILLLINIGNDLIWRIVLFMG
HHCCCEECCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILPAVSVFYLRRKLPETYKFLTRIKPKREELKKLENEIKSKITISLDEVPFSKRFISAIG
HHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHH
ITIISSILWLLYDMYSSTFAIYGPITIAGNLGLNPIEFTYLAQFLAGLPGQIISIYLVDK
HHHHHHHHHHHHHHHHCCEEEEECEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
IGRKPLIVIGYAGVAFWLFMYTMLLMNPYYFGLSIHISNPLKAAESLTGEAALLGLLFYL
CCCCCEEEEEHHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHHHHHCCCHHHHHHHHHHH
MNYLSSAIGPASIIGSAMLTSELVPTKVRGTSQAISVAADRLAAAFSITAFPLLLAKFGL
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
PALLAVYSTIALVSCIITLLLIPETKGVELS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]