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The map label for this gene is glmU [H]

Identifier: 227827988

GI number: 227827988

Start: 1601596

End: 1602678

Strand: Direct

Name: glmU [H]

Synonym: M1425_1724

Alternate gene names: 227827988

Gene position: 1601596-1602678 (Clockwise)

Preceding gene: 227827987

Following gene: 227827990

Centisome position: 61.39

GC content: 37.3

Gene sequence:

>1083_bases
ATGAAAGCTATAGTGTTAGCTGGAGGAAAGGGAGAAGGATTATTGCCATACACTGACAAGGTTCAGAAAGAGGCTATCAC
AGTACTAGGCAAAGCAATAATAAACTACACAATAGATGGTTTAAAGAAAGCAGGCGTAAAAGAATTTGAGATAATCGTAA
ACGAGAAGGGAAATCAAATAGAAGAAGAGGTTGAGAAACTTGATGTATCGTTTGAAACTATAGTACAAAAGAGACAAGGA
ATTGATGGTGCAGTTCTAGATGGTATGGAAAAGATTGATGACGATGTATTTGTGTTGGCATTTGGTGATATTATTGTACC
TGCGGAATTCTACAAAAGCCTTATGGACACTTACATAATGACAGGGAGACAAGCCGTTATACCGTTGGTACCAGTGAGTG
AGGGAACAGAAACTTACGGTCTAGTTAAAATCGTTGACAACAAACTAAAGGTGGTTAAAGAAAGCTCAACCCTAGCATTA
GGTGGAGCTTACATATTACCAAAACCAAAGGACAATTTCACTTCTCTTCTGGATTATATTGATCTTCTTGCTAGTGAAGC
TAAACTCAACTATTTTATTTGGTCAGAGAACTGGGTTGACATAGGTTATCCAGAGGATTTACTATTCGCATTAGAAACGC
TGTTAAGGAGAAAGGAAAGCGTTATATCAGATAAGGCTGAAATTTCGAAAGACGCAATAATTGGGAAGGGAGTTATTGTT
GAAGATAATGCGATAATAGAAGATTATGCGATAATTAAAGGACCAGCTTATATCGGTAAAAACGCTTACGTAGGATCGTT
TTCTTTAGTTAGAGACTATTCCTCCATAGAAGAGGGAGCTAAGATAGGGGCTTACTGTGAAATTGCCCATTCACTAATTG
AACCCTTCGCTGAAGTGGGTTCTAAATCCTATTTGACTTACTCAATAGTGGGTAAAGGAGCTAAGATAGGGGCTTCTGTC
ATAACTGCAAGTTATCCAGCACAATCACTAAGTAGGCCTAGATTCAATAAACTAGGTGCTTTAATTTCACCAGAAAAAGT
AATTAAACATGGAAGTGTAATAGAAGCTGGTATGAAAATTTAA

Upstream 100 bases:

>100_bases
CGCCAATAATTCAACTAATAGCATATTACGCTTCTGTTAAAAGAGGATACGATCCAGATAAGCCTAGAAACCTGGCCAAA
ACAGTAACGGTTGAGTAAAG

Downstream 100 bases:

>100_bases
TAAAAAAGCCTAAATTTCTTTAGCGTTTTCTCTATCTTCTTCTTAAAAGTACTACGGCAGCTACTACTATCACTATTATA
ACTATTACAATACCTATTAT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKAIVLAGGKGEGLLPYTDKVQKEAITVLGKAIINYTIDGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQKRQG
IDGAVLDGMEKIDDDVFVLAFGDIIVPAEFYKSLMDTYIMTGRQAVIPLVPVSEGTETYGLVKIVDNKLKVVKESSTLAL
GGAYILPKPKDNFTSLLDYIDLLASEAKLNYFIWSENWVDIGYPEDLLFALETLLRRKESVISDKAEISKDAIIGKGVIV
EDNAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIGASV
ITASYPAQSLSRPRFNKLGALISPEKVIKHGSVIEAGMKI

Sequences:

>Translated_360_residues
MKAIVLAGGKGEGLLPYTDKVQKEAITVLGKAIINYTIDGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQKRQG
IDGAVLDGMEKIDDDVFVLAFGDIIVPAEFYKSLMDTYIMTGRQAVIPLVPVSEGTETYGLVKIVDNKLKVVKESSTLAL
GGAYILPKPKDNFTSLLDYIDLLASEAKLNYFIWSENWVDIGYPEDLLFALETLLRRKESVISDKAEISKDAIIGKGVIV
EDNAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIGASV
ITASYPAQSLSRPRFNKLGALISPEKVIKHGSVIEAGMKI
>Mature_360_residues
MKAIVLAGGKGEGLLPYTDKVQKEAITVLGKAIINYTIDGLKKAGVKEFEIIVNEKGNQIEEEVEKLDVSFETIVQKRQG
IDGAVLDGMEKIDDDVFVLAFGDIIVPAEFYKSLMDTYIMTGRQAVIPLVPVSEGTETYGLVKIVDNKLKVVKESSTLAL
GGAYILPKPKDNFTSLLDYIDLLASEAKLNYFIWSENWVDIGYPEDLLFALETLLRRKESVISDKAEISKDAIIGKGVIV
EDNAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVGSKSYLTYSIVGKGAKIGASV
ITASYPAQSLSRPRFNKLGALISPEKVIKHGSVIEAGMKI

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=345, Percent_Identity=24.0579710144928, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 39205; Mature: 39205

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVLAGGKGEGLLPYTDKVQKEAITVLGKAIINYTIDGLKKAGVKEFEIIVNEKGNQI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
EEEVEKLDVSFETIVQKRQGIDGAVLDGMEKIDDDVFVLAFGDIIVPAEFYKSLMDTYIM
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHH
TGRQAVIPLVPVSEGTETYGLVKIVDNKLKVVKESSTLALGGAYILPKPKDNFTSLLDYI
CCCCEEEEEEECCCCCCCEEEEEEECCHHHEEECCCEEEECCEEECCCCCCHHHHHHHHH
DLLASEAKLNYFIWSENWVDIGYPEDLLFALETLLRRKESVISDKAEISKDAIIGKGVIV
HHHHCCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEE
EDNAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVG
ECCCEEECCCEEECCCEECCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
SKSYLTYSIVGKGAKIGASVITASYPAQSLSRPRFNKLGALISPEKVIKHGSVIEAGMKI
CCCEEEEEEECCCCHHCHHHEEECCCHHHCCCCCHHHHCCCCCHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MKAIVLAGGKGEGLLPYTDKVQKEAITVLGKAIINYTIDGLKKAGVKEFEIIVNEKGNQI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
EEEVEKLDVSFETIVQKRQGIDGAVLDGMEKIDDDVFVLAFGDIIVPAEFYKSLMDTYIM
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHH
TGRQAVIPLVPVSEGTETYGLVKIVDNKLKVVKESSTLALGGAYILPKPKDNFTSLLDYI
CCCCEEEEEEECCCCCCCEEEEEEECCHHHEEECCCEEEECCEEECCCCCCHHHHHHHHH
DLLASEAKLNYFIWSENWVDIGYPEDLLFALETLLRRKESVISDKAEISKDAIIGKGVIV
HHHHCCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEE
EDNAIIEDYAIIKGPAYIGKNAYVGSFSLVRDYSSIEEGAKIGAYCEIAHSLIEPFAEVG
ECCCEEECCCEEECCCEECCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
SKSYLTYSIVGKGAKIGASVITASYPAQSLSRPRFNKLGALISPEKVIKHGSVIEAGMKI
CCCEEEEEEECCCCHHCHHHEEECCCHHHCCCCCHHHHCCCCCHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]