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The map label for this gene is yggV [C]

Identifier: 227827942

GI number: 227827942

Start: 1551616

End: 1552194

Strand: Direct

Name: yggV [C]

Synonym: M1425_1675

Alternate gene names: 227827942

Gene position: 1551616-1552194 (Clockwise)

Preceding gene: 227827941

Following gene: 227827944

Centisome position: 59.48

GC content: 33.85

Gene sequence:

>579_bases
ATGTTGAGGAGAGACGTAAGAATAGGAGTGGTAACGAGTAATGAGAATAAGTTTATGGAATTAAAAGAACTTGCTAAGAG
CTTTAATATAGAGTTAGAACAGCTTAAAGGAGAGAAAATAGAAATACAAAGTGATAATTTAGAGGAAATATCTAAAACAG
CTGCATATTTAGCGTATTTGACCTTCAGAAGACCATTAATAGTAGATGATAGCGGGTTATTTATAGAAACCTTACAGAAT
TTTCCTGGTCCCTACACAAATTTTGTTAAGAACACAATTGGACTTAAAGGTATACTAAAATTGCTCGAAGACCTAAAAGA
TAGGTCAGCGTATTTCATGACTGTATTGACGTTTACTGACGGAAAAATAATTAAAACATTTAATGGTATCGTAAAGGGAG
TTATTTCTGAAGAGATTAGGGGTAATTCAGGTTTTGGATTTGACCCCATATTTATCCCAGAAGGAGAAAAGAGAACTTTC
GCGGAGATGTCATTGGAGGAGAAGAATAAATACTCACATAGGGCAAGAGCGTTTGCTAAATTTGCTGATTTCTTAATGAG
CTATCTTGAAAAAGCATAA

Upstream 100 bases:

>100_bases
ATTATCTACAATTCATTTGTGGAGGGTTACAGAACAATCATGGGTGGAAAGACTGACGAAATATTAGAGCTAGTAAAGGA
TATTAGGATGAGGGGAAGAT

Downstream 100 bases:

>100_bases
AATAAGTAGTTCTTGAAATAAACTATTTATACCTTAAAGTTTCTTTTATACTATCCTCATTTAGGTCTTCATAGTATTTC
TTGTAATAGTCTTCAATGTA

Product: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLRRDVRIGVVTSNENKFMELKELAKSFNIELEQLKGEKIEIQSDNLEEISKTAAYLAYLTFRRPLIVDDSGLFIETLQN
FPGPYTNFVKNTIGLKGILKLLEDLKDRSAYFMTVLTFTDGKIIKTFNGIVKGVISEEIRGNSGFGFDPIFIPEGEKRTF
AEMSLEEKNKYSHRARAFAKFADFLMSYLEKA

Sequences:

>Translated_192_residues
MLRRDVRIGVVTSNENKFMELKELAKSFNIELEQLKGEKIEIQSDNLEEISKTAAYLAYLTFRRPLIVDDSGLFIETLQN
FPGPYTNFVKNTIGLKGILKLLEDLKDRSAYFMTVLTFTDGKIIKTFNGIVKGVISEEIRGNSGFGFDPIFIPEGEKRTF
AEMSLEEKNKYSHRARAFAKFADFLMSYLEKA
>Mature_192_residues
MLRRDVRIGVVTSNENKFMELKELAKSFNIELEQLKGEKIEIQSDNLEEISKTAAYLAYLTFRRPLIVDDSGLFIETLQN
FPGPYTNFVKNTIGLKGILKLLEDLKDRSAYFMTVLTFTDGKIIKTFNGIVKGVISEEIRGNSGFGFDPIFIPEGEKRTF
AEMSLEEKNKYSHRARAFAKFADFLMSYLEKA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=185, Percent_Identity=31.8918918918919, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI31657144, Length=162, Percent_Identity=31.4814814814815, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17556833, Length=179, Percent_Identity=31.8435754189944, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322529, Length=185, Percent_Identity=31.8918918918919, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920712, Length=187, Percent_Identity=34.2245989304813, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21975; Mature: 21975

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRDVRIGVVTSNENKFMELKELAKSFNIELEQLKGEKIEIQSDNLEEISKTAAYLAYL
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHH
TFRRPLIVDDSGLFIETLQNFPGPYTNFVKNTIGLKGILKLLEDLKDRSAYFMTVLTFTD
HHCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GKIIKTFNGIVKGVISEEIRGNSGFGFDPIFIPEGEKRTFAEMSLEEKNKYSHRARAFAK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FADFLMSYLEKA
HHHHHHHHHHCC
>Mature Secondary Structure
MLRRDVRIGVVTSNENKFMELKELAKSFNIELEQLKGEKIEIQSDNLEEISKTAAYLAYL
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHH
TFRRPLIVDDSGLFIETLQNFPGPYTNFVKNTIGLKGILKLLEDLKDRSAYFMTVLTFTD
HHCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GKIIKTFNGIVKGVISEEIRGNSGFGFDPIFIPEGEKRTFAEMSLEEKNKYSHRARAFAK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FADFLMSYLEKA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA