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The map label for this gene is gcp

Identifier: 227827940

GI number: 227827940

Start: 1550002

End: 1550997

Strand: Direct

Name: gcp

Synonym: M1425_1673

Alternate gene names: 227827940

Gene position: 1550002-1550997 (Clockwise)

Preceding gene: 227827939

Following gene: 227827941

Centisome position: 59.41

GC content: 37.85

Gene sequence:

>996_bases
ATGTTAGTACTGGGTATCGAATCTACCGCCCATACTCTCGGAGTAGGAATAGCAAAAGATCAACCACCCTACATATTGGC
AAACGAAAGGGATACTTTTGTTCCCAAAGAGGGTGGTATGAAGCCTGGAGATCTACTAAAACACCATGCTGAAGTCTCAG
GGACAATACTGAGAAGAGCCCTAGAGAAAGCTAATATTAGTATAAATGATATTAATTATATAGCAGTAGCTTTAGGACCT
GGTATAGGACCAGCATTGAGAGTTGGTGCTACACTAGCGAGAGCGTTATCGCTAAAGTATAATAAGAAATTAGTTCCAGT
GAATCACGGTATAGGACATATTGAAATAGGGTATTTAACAACTGAGGCCAAAGACCCTTTAATCTTATACCTCTCAGGCG
GAAATACAATCATAACTACCTTCTATAAAGGGAGGTTTAGAATTTTTGGAGAAACATTAGATATTGCATTAGGAAACATG
ATGGATGTATTTGTAAGAGAGGTGAACTTGGCACCACCATACATTATTAACGGAAAACACGCAATTGATATTTGCTCAGA
AAAAGGAAGCAAATTACTTAAATTACCTTACGTTGTTAAGGGTCAAGATATGTCATTTTCTGGATTACTTACAGCAGCAT
TAAGGTTAGTCGGAAAGGAAAAGTTAGAAGATATTTGTTACTCAATAAGGGAAATAGCATTCGATATGTTATTGGAAGCT
ACAGAAAGGGCACTGGCACTTACCTCAAAAAAGGAGTTAATGATAGTTGGAGGAGTAGCAGCTAGTGTAAGTTTGAGAAA
AAAGTTGGAAGAGTTGGGAAAAGAGTGGGACGTACAAATTAAAATAGTACCGCCAGAATTTGCGGGAGATAATGGGGCGA
TGATAGCTTATGCTGGTATGTTGGCTGCATCAAAAGGTGTATTTATTGATGTTGATAAATCATACATAAGACCTAGATGG
AGAGTAGACGAGGTAGATATTCCTTGGAGAAATTAA

Upstream 100 bases:

>100_bases
CGGAAGTATAATGGCTCACCACTTAAAACCAAATGAGAGATGGTCTTGTGGAAAATGTGGTTACACTGAGTTTATAGGCA
CTTCAAAGAAAAGATAAAAT

Downstream 100 bases:

>100_bases
GGTTAATTAAGCGTGGTGCAGAATCCAACATATATGAAGGATATTTTTTGGGTATTCGTGCAATATTTAAACAAAGAATT
AAGAAAAGTTATAGAAATCC

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MLVLGIESTAHTLGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRALEKANISINDINYIAVALGP
GIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLTTEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNM
MDVFVREVNLAPPYIINGKHAIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEA
TERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRW
RVDEVDIPWRN

Sequences:

>Translated_331_residues
MLVLGIESTAHTLGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRALEKANISINDINYIAVALGP
GIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLTTEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNM
MDVFVREVNLAPPYIINGKHAIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEA
TERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRW
RVDEVDIPWRN
>Mature_331_residues
MLVLGIESTAHTLGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRALEKANISINDINYIAVALGP
GIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLTTEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNM
MDVFVREVNLAPPYIINGKHAIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEA
TERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRW
RVDEVDIPWRN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI8923380, Length=340, Percent_Identity=41.1764705882353, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI116812636, Length=354, Percent_Identity=25.7062146892655, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=31.858407079646, Blast_Score=140, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=340, Percent_Identity=42.0588235294118, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322891, Length=373, Percent_Identity=36.4611260053619, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6320099, Length=367, Percent_Identity=29.1553133514986, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357207, Length=353, Percent_Identity=38.2436260623229, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI20129063, Length=367, Percent_Identity=25.3405994550409, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SULIA (C3N6N9)

Other databases:

- EMBL:   CP001401
- RefSeq:   YP_002843709.1
- GeneID:   7812453
- GenomeReviews:   CP001401_GR
- KEGG:   sim:M1627_1789
- OMA:   TQRFRTD
- ProtClustDB:   PRK14878
- GO:   GO:0006508
- HAMAP:   MF_01446
- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03722
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36199; Mature: 36199

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESTAHTLGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRA
CEEEEECCCCHHHEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LEKANISINDINYIAVALGPGIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLT
HHHCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEE
TEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNMMDVFVREVNLAPPYIINGKH
ECCCCCEEEEEECCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
AIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEA
EEEEECCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGM
HHHHHEECCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEHH
LAASKGVFIDVDKSYIRPRWRVDEVDIPWRN
HHCCCCEEEEECHHHCCCCCEECCCCCCCCC
>Mature Secondary Structure
MLVLGIESTAHTLGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRA
CEEEEECCCCHHHEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LEKANISINDINYIAVALGPGIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLT
HHHCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEE
TEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNMMDVFVREVNLAPPYIINGKH
ECCCCCEEEEEECCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
AIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEA
EEEEECCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGM
HHHHHEECCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEHH
LAASKGVFIDVDKSYIRPRWRVDEVDIPWRN
HHCCCCEEEEECHHHCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA