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The map label for this gene is 227827908

Identifier: 227827908

GI number: 227827908

Start: 1529609

End: 1530211

Strand: Direct

Name: 227827908

Synonym: M1425_1641

Alternate gene names: NA

Gene position: 1529609-1530211 (Clockwise)

Preceding gene: 227827907

Following gene: 227827909

Centisome position: 58.63

GC content: 35.66

Gene sequence:

>603_bases
ATGTCTTGGGATATAAGATACTTAGAATGGAGATTCGCCAACCTAAATGAGATCACTTCCTTTTTACTTGCTGCCTTATC
TTTAGCAGTAGCTTATATACGCCCAACATCCATACTTTCAGATCCAATAGGTAGTATAATCATACCATATATCGTAGCAT
TATTAGCTATAATACCACATGAAATAGGCCACAGACAAGCTGCGAGAAGATATGGTTGTTTCTCTAGATTTACTTTAAGT
TTTTCAGGGTTTTGGACAACGTTAATACTGAATATAATTGGTAGCTTCGTAGGTATCTTAGTTTTCTTTTCGGGATACAC
ATCAATATCTTGTGGATTTCTTAATAGAGACGTTGAGGGAAAAACAGCTCTAGCTGGACCTCTAACTAACATAATATTAG
GATTTGTTGGCCTTATTGGTGCATCGTTAGTGCCTTTTAGCCTTGTTGGCTTATTTTTCTTTGAATTAGCTAGGTTTAAC
TTCTGGGTAGCATTCTTTAACTTGCTTCCATTCTGGGTTTTAGACGGATTAAAGATCTTTAGATGGAACATGATAGTGTG
GGCAGTATTGATAATCATTGCATTCGCATTAACATTTCTATAA

Upstream 100 bases:

>100_bases
ATGACAAAAAAGCGTTATTATGGAAAATAGATAGTACAAACATTCGATATGTAAGCAATAATTTAATACCCTCAGAGTTG
TTAAGATTAATAAGATAGGT

Downstream 100 bases:

>100_bases
TGGTGAATAAAGTGATAATAAAAAAAATAATAGGTATATCAACTTTTTTCTTAATGTTTCTTGTTACTTTGGGTTTTATG
GTAGGTTTATTAGCAACTTT

Product: peptidase M50

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSWDIRYLEWRFANLNEITSFLLAALSLAVAYIRPTSILSDPIGSIIIPYIVALLAIIPHEIGHRQAARRYGCFSRFTLS
FSGFWTTLILNIIGSFVGILVFFSGYTSISCGFLNRDVEGKTALAGPLTNIILGFVGLIGASLVPFSLVGLFFFELARFN
FWVAFFNLLPFWVLDGLKIFRWNMIVWAVLIIIAFALTFL

Sequences:

>Translated_200_residues
MSWDIRYLEWRFANLNEITSFLLAALSLAVAYIRPTSILSDPIGSIIIPYIVALLAIIPHEIGHRQAARRYGCFSRFTLS
FSGFWTTLILNIIGSFVGILVFFSGYTSISCGFLNRDVEGKTALAGPLTNIILGFVGLIGASLVPFSLVGLFFFELARFN
FWVAFFNLLPFWVLDGLKIFRWNMIVWAVLIIIAFALTFL
>Mature_199_residues
SWDIRYLEWRFANLNEITSFLLAALSLAVAYIRPTSILSDPIGSIIIPYIVALLAIIPHEIGHRQAARRYGCFSRFTLSF
SGFWTTLILNIIGSFVGILVFFSGYTSISCGFLNRDVEGKTALAGPLTNIILGFVGLIGASLVPFSLVGLFFFELARFNF
WVAFFNLLPFWVLDGLKIFRWNMIVWAVLIIIAFALTFL

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 22491; Mature: 22360

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDIRYLEWRFANLNEITSFLLAALSLAVAYIRPTSILSDPIGSIIIPYIVALLAIIPH
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EIGHRQAARRYGCFSRFTLSFSGFWTTLILNIIGSFVGILVFFSGYTSISCGFLNRDVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC
KTALAGPLTNIILGFVGLIGASLVPFSLVGLFFFELARFNFWVAFFNLLPFWVLDGLKIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWNMIVWAVLIIIAFALTFL
HHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SWDIRYLEWRFANLNEITSFLLAALSLAVAYIRPTSILSDPIGSIIIPYIVALLAIIPH
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EIGHRQAARRYGCFSRFTLSFSGFWTTLILNIIGSFVGILVFFSGYTSISCGFLNRDVEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC
KTALAGPLTNIILGFVGLIGASLVPFSLVGLFFFELARFNFWVAFFNLLPFWVLDGLKIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWNMIVWAVLIIIAFALTFL
HHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]