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The map label for this gene is 227827665

Identifier: 227827665

GI number: 227827665

Start: 1317581

End: 1318204

Strand: Direct

Name: 227827665

Synonym: M1425_1394

Alternate gene names: NA

Gene position: 1317581-1318204 (Clockwise)

Preceding gene: 227827664

Following gene: 227827666

Centisome position: 50.5

GC content: 33.17

Gene sequence:

>624_bases
TTGGCAAGTGTTAGAATTGTTGAATTCCGTGGATTTAAGTTATGTTTAAATGATCAGACGTATGAACCTTCTGATGATAC
CGATATTCTACTTAACCTACTAAAGGTAGGTAAAGGGGAAAAGGTCTTAGATATGGGATCTGGTTCTGGGATTTTAGGAA
TATGGTCTCTGATAATGGGAGGAAAGGTAATATTTGTAGATATAAATCCATATGCGACGACATCTACATTATGTTCCTTA
AAAGTTAATAATTTGTATAATAGTCCAAATTATTTAGGTGTTCTTAATTGCGATTTGTTGTCTTGTCTTAGAAAGTATGA
TTTTGATGTAGCTATTTTTAACCCTCCCTATTTACCAGTGGAGGAGTATAATGAATGGATAGGGTATAGTTGGTCTGGTG
GAAAGGATGGAAGTAAAGTTCTTGTTGATTTTTTAAAAACTGTAAAAGCTAATAGAATTTATACCCTATATTCTTCTTTA
AGTGATGAAGATAGGATATTATATGCTATTAATAAGGGAAGATTCAAAATTTCACAGAAGTATGAGAAGGTTATTGGGTA
TGAGAGATTGATAGGATTGGAGTTGGTGAAGGAGGATGATAAGGGTAGTTTTAGTAGAGCCTGA

Upstream 100 bases:

>100_bases
TTTCATGTATTAGTAGATATAGGAATAAAACTTTAAAAAATGCTTCTAAGTTGTGTGGGCTTAGTTCAGATAATAATTTG
AAGGTGAGGGAATTTAAACC

Downstream 100 bases:

>100_bases
AGGTGAATATAACATTGGTTTTGTTGCAAGGTTATGTAGAAATTTTTCGGTTGATGAACTCTATATAGTTAATCCAAGGG
CCAACGTTTCTGAGGCTTTC

Product: methylase

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MASVRIVEFRGFKLCLNDQTYEPSDDTDILLNLLKVGKGEKVLDMGSGSGILGIWSLIMGGKVIFVDINPYATTSTLCSL
KVNNLYNSPNYLGVLNCDLLSCLRKYDFDVAIFNPPYLPVEEYNEWIGYSWSGGKDGSKVLVDFLKTVKANRIYTLYSSL
SDEDRILYAINKGRFKISQKYEKVIGYERLIGLELVKEDDKGSFSRA

Sequences:

>Translated_207_residues
MASVRIVEFRGFKLCLNDQTYEPSDDTDILLNLLKVGKGEKVLDMGSGSGILGIWSLIMGGKVIFVDINPYATTSTLCSL
KVNNLYNSPNYLGVLNCDLLSCLRKYDFDVAIFNPPYLPVEEYNEWIGYSWSGGKDGSKVLVDFLKTVKANRIYTLYSSL
SDEDRILYAINKGRFKISQKYEKVIGYERLIGLELVKEDDKGSFSRA
>Mature_206_residues
ASVRIVEFRGFKLCLNDQTYEPSDDTDILLNLLKVGKGEKVLDMGSGSGILGIWSLIMGGKVIFVDINPYATTSTLCSLK
VNNLYNSPNYLGVLNCDLLSCLRKYDFDVAIFNPPYLPVEEYNEWIGYSWSGGKDGSKVLVDFLKTVKANRIYTLYSSLS
DEDRILYAINKGRFKISQKYEKVIGYERLIGLELVKEDDKGSFSRA

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Caenorhabditis elegans, GI193204212, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320344, Length=163, Percent_Identity=33.7423312883436, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: NA

Molecular weight: Translated: 23320; Mature: 23189

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVRIVEFRGFKLCLNDQTYEPSDDTDILLNLLKVGKGEKVLDMGSGSGILGIWSLIMG
CCCEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHC
GKVIFVDINPYATTSTLCSLKVNNLYNSPNYLGVLNCDLLSCLRKYDFDVAIFNPPYLPV
CEEEEEECCCCCCCHHEEEEEECCCCCCCCEEEEECHHHHHHHHHCCCCEEEECCCCCCH
EEYNEWIGYSWSGGKDGSKVLVDFLKTVKANRIYTLYSSLSDEDRILYAINKGRFKISQK
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCEEEHHHH
YEKVIGYERLIGLELVKEDDKGSFSRA
HHHHHHHHHHHHEEEEECCCCCCCCCC
>Mature Secondary Structure 
ASVRIVEFRGFKLCLNDQTYEPSDDTDILLNLLKVGKGEKVLDMGSGSGILGIWSLIMG
CCEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHC
GKVIFVDINPYATTSTLCSLKVNNLYNSPNYLGVLNCDLLSCLRKYDFDVAIFNPPYLPV
CEEEEEECCCCCCCHHEEEEEECCCCCCCCEEEEECHHHHHHHHHCCCCEEEECCCCCCH
EEYNEWIGYSWSGGKDGSKVLVDFLKTVKANRIYTLYSSLSDEDRILYAINKGRFKISQK
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCEEEHHHH
YEKVIGYERLIGLELVKEDDKGSFSRA
HHHHHHHHHHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]