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The map label for this gene is ksgA [H]

Identifier: 227827664

GI number: 227827664

Start: 1317033

End: 1317629

Strand: Direct

Name: ksgA [H]

Synonym: M1425_1393

Alternate gene names: 227827664

Gene position: 1317033-1317629 (Clockwise)

Preceding gene: 227827663

Following gene: 227827665

Centisome position: 50.48

GC content: 29.65

Gene sequence:

>597_bases
GTGGATACTGGAATCAGACCTATTTTAGAGATTGGATGTGGAAAAGGAAATATTACTAAATTTTTAGAACCGGATATTTG
TATTGAATTAGATGAGAAAATGACAGACTATTTGAAAGATTATAATCTTGTAATAGCAGATGCAAGATATTTGCCAATAC
TAAGGGGTCAATTAGTTTCTTCTCTACCTTACCAGATAACTTCAGATTTTTTCAAGGAGGTAGTTAAACTTGACAATATA
AGTAAGCTTATACTGATTTTGCAAAAGGATTTTGTGGATAAGATTCTTAATGATCCTACATATATTTCTTTTTTGCTTAA
TTATGTGTTTGATATACAGACTAAAGACATAATTCCACCAAGATGTTTCAGTCCTCGTCCAAAAGTCTATTCAATTATTA
CAGTTTTTAATAGGGTAAGAGAATATAATGACGATGTTGATAGTTTAATTTCATGTATTAGTAGATATAGGAATAAAACT
TTAAAAAATGCTTCTAAGTTGTGTGGGCTTAGTTCAGATAATAATTTGAAGGTGAGGGAATTTAAACCTTGGCAAGTGTT
AGAATTGTTGAATTCCGTGGATTTAAGTTATGTTTAA

Upstream 100 bases:

>100_bases
AACAGCAATTCATTTACGTGGGTTATATTGAAAAGCTAAAGTAAGGCTTTCACAAGTTTTTCTTATTGATAAGAGTTTTA
TAGAAAAGTTTATTTCATAC

Downstream 100 bases:

>100_bases
ATGATCAGACGTATGAACCTTCTGATGATACCGATATTCTACTTAACCTACTAAAGGTAGGTAAAGGGGAAAAGGTCTTA
GATATGGGATCTGGTTCTGG

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MDTGIRPILEIGCGKGNITKFLEPDICIELDEKMTDYLKDYNLVIADARYLPILRGQLVSSLPYQITSDFFKEVVKLDNI
SKLILILQKDFVDKILNDPTYISFLLNYVFDIQTKDIIPPRCFSPRPKVYSIITVFNRVREYNDDVDSLISCISRYRNKT
LKNASKLCGLSSDNNLKVREFKPWQVLELLNSVDLSYV

Sequences:

>Translated_198_residues
MDTGIRPILEIGCGKGNITKFLEPDICIELDEKMTDYLKDYNLVIADARYLPILRGQLVSSLPYQITSDFFKEVVKLDNI
SKLILILQKDFVDKILNDPTYISFLLNYVFDIQTKDIIPPRCFSPRPKVYSIITVFNRVREYNDDVDSLISCISRYRNKT
LKNASKLCGLSSDNNLKVREFKPWQVLELLNSVDLSYV
>Mature_198_residues
MDTGIRPILEIGCGKGNITKFLEPDICIELDEKMTDYLKDYNLVIADARYLPILRGQLVSSLPYQITSDFFKEVVKLDNI
SKLILILQKDFVDKILNDPTYISFLLNYVFDIQTKDIIPPRCFSPRPKVYSIITVFNRVREYNDDVDSLISCISRYRNKT
LKNASKLCGLSSDNNLKVREFKPWQVLELLNSVDLSYV

Specific function: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: NA

Molecular weight: Translated: 22901; Mature: 22901

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTGIRPILEIGCGKGNITKFLEPDICIELDEKMTDYLKDYNLVIADARYLPILRGQLVS
CCCCCCHHHHHCCCCCCCCHHCCCCCEEEHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
SLPYQITSDFFKEVVKLDNISKLILILQKDFVDKILNDPTYISFLLNYVFDIQTKDIIPP
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
RCFSPRPKVYSIITVFNRVREYNDDVDSLISCISRYRNKTLKNASKLCGLSSDNNLKVRE
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FKPWQVLELLNSVDLSYV
CCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDTGIRPILEIGCGKGNITKFLEPDICIELDEKMTDYLKDYNLVIADARYLPILRGQLVS
CCCCCCHHHHHCCCCCCCCHHCCCCCEEEHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
SLPYQITSDFFKEVVKLDNISKLILILQKDFVDKILNDPTYISFLLNYVFDIQTKDIIPP
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
RCFSPRPKVYSIITVFNRVREYNDDVDSLISCISRYRNKTLKNASKLCGLSSDNNLKVRE
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FKPWQVLELLNSVDLSYV
CCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]