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The map label for this gene is yceI [H]

Identifier: 227826783

GI number: 227826783

Start: 339211

End: 340347

Strand: Direct

Name: yceI [H]

Synonym: M1425_0392

Alternate gene names: 227826783

Gene position: 339211-340347 (Clockwise)

Preceding gene: 227826780

Following gene: 227826784

Centisome position: 13.0

GC content: 38.08

Gene sequence:

>1137_bases
ATGAACTGGAAATTAGTAGTCTTGGTAATCGGGATGTCGTTAACCTTTTGGGATATATTCAACGTTCCTTACATTATAAA
TTACGCTAGAAAGCAGTTTGAAGTCTCTACAGTTATCGCTAACTTACCATTATCTGCTGAAATGATTGGATATGCAATTG
GTGGAGTAATAAACGGATTGCTTTCATCATTCAAGGGAAGAAAAATTGGGCTATTAACTTCCATGGGACTTGTATCATTA
GGATCCCTAATCGGCTTTTTATCGCAAACGTTTTCATGGATAATCATAGCAGAATTCATTATAGGATTAGGAATAGAAGG
AGAAATCAGTGTAGTGCCAACTTATATATCAGAAACCGTATCTGCTGAAAGGAGAGGTAGGGCAGTTGGGTTAGTTACAG
CCTCTGGCTTTTTAACAACGTTGATTGTGGGACCTATTGCAGTAGTCTTAGGAGGCGAATGGAGATTACTTTTCTTGGCC
GGACTTCTAGTTTCTCTGATTGCGTTAATTACTAGGGTTTGGCTGCCTGAATCTCCAATGTGGATTGCCAAAAAGGAGAT
GAAGTTAAGCTGGGATTTCGGAATCCTCATGATGACTATCGTTTGGTTCTTAAGCTATTTTACGGGTTATGCGTTATTTT
CTGATCCCATCTTTACCTTTATTAGCTCTCACGGTTTTACTAATCCTGCGTTGTACTTCACTTATATTCTATATGGTGAT
CCACTGGGTGTTGTAATTGGTACGTTATTGAACGATAACTTTGAACGCAAGTATAGCGTATCATTAGTAAACATTCTAGC
TGGGCTGGTAATAGTAGCGTGGTTTTTCAGTAGTGGTTCTCTAATGCTAATAATGGGATTTATGGAAATGTTCTTGCAAG
GTTTCAAATTCCCCACGATGTACACTTACACTGCTGAAATTTTTAGAACGAGAATTAGAACTTTAGGTTATGGTGTTGCT
GATGGTATTGGACACTTAGGCGGTGCAATTGGTCCAATAATCTTTTCCTTAGCGTATGTTAACATGCGATTATTATCATT
TATAGTTTTAGCAGTTGTAGCTGGTATTACAGGGGCTATAGTGGGCATATGGGGAATTAAAACTACTGGAAAACCATTAG
ACAGTATTAAAGGATAG

Upstream 100 bases:

>100_bases
CGTGCTTTTTAGCTTGCCATTTAATCCAATACTGCAAACGACGGTATTGTGTCAAGTATAGTTTGTAAGTTTTATAAACT
TTAAACTTTCAGAAAAAAGT

Downstream 100 bases:

>100_bases
TATTTTTGTTCCTTTTACTTTTGATTTTCTATATATAAGTGTTATCCTTAAAAAGGTATGGTTAGCTTGGAGATCGTAAG
CCAAGATTCAATATCATAGC

Product: major facilitator superfamily MFS_1

Products: Proton [Cytoplasm]; N-acetylneuraminate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNWKLVVLVIGMSLTFWDIFNVPYIINYARKQFEVSTVIANLPLSAEMIGYAIGGVINGLLSSFKGRKIGLLTSMGLVSL
GSLIGFLSQTFSWIIIAEFIIGLGIEGEISVVPTYISETVSAERRGRAVGLVTASGFLTTLIVGPIAVVLGGEWRLLFLA
GLLVSLIALITRVWLPESPMWIAKKEMKLSWDFGILMMTIVWFLSYFTGYALFSDPIFTFISSHGFTNPALYFTYILYGD
PLGVVIGTLLNDNFERKYSVSLVNILAGLVIVAWFFSSGSLMLIMGFMEMFLQGFKFPTMYTYTAEIFRTRIRTLGYGVA
DGIGHLGGAIGPIIFSLAYVNMRLLSFIVLAVVAGITGAIVGIWGIKTTGKPLDSIKG

Sequences:

>Translated_378_residues
MNWKLVVLVIGMSLTFWDIFNVPYIINYARKQFEVSTVIANLPLSAEMIGYAIGGVINGLLSSFKGRKIGLLTSMGLVSL
GSLIGFLSQTFSWIIIAEFIIGLGIEGEISVVPTYISETVSAERRGRAVGLVTASGFLTTLIVGPIAVVLGGEWRLLFLA
GLLVSLIALITRVWLPESPMWIAKKEMKLSWDFGILMMTIVWFLSYFTGYALFSDPIFTFISSHGFTNPALYFTYILYGD
PLGVVIGTLLNDNFERKYSVSLVNILAGLVIVAWFFSSGSLMLIMGFMEMFLQGFKFPTMYTYTAEIFRTRIRTLGYGVA
DGIGHLGGAIGPIIFSLAYVNMRLLSFIVLAVVAGITGAIVGIWGIKTTGKPLDSIKG
>Mature_378_residues
MNWKLVVLVIGMSLTFWDIFNVPYIINYARKQFEVSTVIANLPLSAEMIGYAIGGVINGLLSSFKGRKIGLLTSMGLVSL
GSLIGFLSQTFSWIIIAEFIIGLGIEGEISVVPTYISETVSAERRGRAVGLVTASGFLTTLIVGPIAVVLGGEWRLLFLA
GLLVSLIALITRVWLPESPMWIAKKEMKLSWDFGILMMTIVWFLSYFTGYALFSDPIFTFISSHGFTNPALYFTYILYGD
PLGVVIGTLLNDNFERKYSVSLVNILAGLVIVAWFFSSGSLMLIMGFMEMFLQGFKFPTMYTYTAEIFRTRIRTLGYGVA
DGIGHLGGAIGPIIFSLAYVNMRLLSFIVLAVVAGITGAIVGIWGIKTTGKPLDSIKG

Specific function: May Be A Sugar-Cation Symporter Involved In Sialic Acid Transport As It Is Required For Sialic Acid Uptake. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082231, Length=182, Percent_Identity=29.6703296703297, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41361; Mature: 41361

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWKLVVLVIGMSLTFWDIFNVPYIINYARKQFEVSTVIANLPLSAEMIGYAIGGVINGL
CCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSSFKGRKIGLLTSMGLVSLGSLIGFLSQTFSWIIIAEFIIGLGIEGEISVVPTYISETV
HHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHH
SAERRGRAVGLVTASGFLTTLIVGPIAVVLGGEWRLLFLAGLLVSLIALITRVWLPESPM
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
WIAKKEMKLSWDFGILMMTIVWFLSYFTGYALFSDPIFTFISSHGFTNPALYFTYILYGD
EEEHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHCCC
PLGVVIGTLLNDNFERKYSVSLVNILAGLVIVAWFFSSGSLMLIMGFMEMFLQGFKFPTM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCH
YTYTAEIFRTRIRTLGYGVADGIGHLGGAIGPIIFSLAYVNMRLLSFIVLAVVAGITGAI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIWGIKTTGKPLDSIKG
HHHCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNWKLVVLVIGMSLTFWDIFNVPYIINYARKQFEVSTVIANLPLSAEMIGYAIGGVINGL
CCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSSFKGRKIGLLTSMGLVSLGSLIGFLSQTFSWIIIAEFIIGLGIEGEISVVPTYISETV
HHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHH
SAERRGRAVGLVTASGFLTTLIVGPIAVVLGGEWRLLFLAGLLVSLIALITRVWLPESPM
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
WIAKKEMKLSWDFGILMMTIVWFLSYFTGYALFSDPIFTFISSHGFTNPALYFTYILYGD
EEEHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHCCC
PLGVVIGTLLNDNFERKYSVSLVNILAGLVIVAWFFSSGSLMLIMGFMEMFLQGFKFPTM
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCH
YTYTAEIFRTRIRTLGYGVADGIGHLGGAIGPIIFSLAYVNMRLLSFIVLAVVAGITGAI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIWGIKTTGKPLDSIKG
HHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; N-acetylneuraminate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + N-acetylneuraminate [Periplasm] = Proton [Cytoplasm] + N-acetylneuraminate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]