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The map label for this gene is yodF [H]

Identifier: 227826675

GI number: 227826675

Start: 231703

End: 233220

Strand: Direct

Name: yodF [H]

Synonym: M1425_0266

Alternate gene names: 227826675

Gene position: 231703-233220 (Clockwise)

Preceding gene: 227826674

Following gene: 227826676

Centisome position: 8.88

GC content: 38.54

Gene sequence:

>1518_bases
ATGTTAGGGCTAGCTGGAATAATCGTCTTTATAGCACTTTTCATAGTATTCATATTCCTTGGATTTTATGGGGCTTTTTG
GAGAAAAGGAAATTTGGATTTGCTTCATGAATGGGGATTAGCAGGGAGAAGGTTAGGTACTGTTCTAGTATGGTTCTTAA
TGGGTGCAGACTTATACACAGCATATACATTTATTGCAGTACCATCAAGCCTTTACGCAAAAGGTGCAATATATTTCTTC
GCAGTACCGTATGTTTCTTTAACCTTTGCTATAGCGATGTTAACAATGCCTAAACTATGGATTGTTTCAAGAAATAGAGG
TTATGTGACGGCAGCTGATTTCGTGAAAGATAGATTCAACAGTAGCATTTTAGCTGCTTTAATAGCGTTAACTGGTGTAG
TAGCTGAATTACCTTATATAGCATTACAAATAGTAGGTATGAAGTCAGTCCTACAGATGATGTTATTAGGAATAGGTAAC
GCGGCCTTAGTGTCTGAAATTTCCCTAATAGTTTCCTTCATAATTTTAGCGGCATTTACATATACTTCTGGCCTTAGGGG
TGCTGCGTTAACTGGAGTTTTTAAAGATATTTTGATCTGGATCACGGTTATATCGGTAATCGTAATCGTACCACTACAAT
ATGGGGGTTTCACTCACGCCTTTAGCGTTATAAACTCAGCAAACCTTTCAGCAAGATATACTACATTACCAAGTAACTTA
CAAATAGCATATTGGAGTTTATTCTTAGGTAGTGCACTAGCCCTATACCTTTATCCACATTCAATAAACGGTTCATTAAG
CGCCGATGATAAGAATAGATTAATGTATAGTACAGCATTGTTGCCAATTTATGGTATTGGTCTAGCGATAATAGCATTAT
TTGGTATTTTAGTTTATGCGGTACCAAACGCATTGAGTGTTGTATCTAAATATGGGGGTGCCCTTGTAGTTCCTGCGTTA
ATAACGTCAACCATGCCAGATTGGGCTGCTGGTATAATGCTACTAGGTATATTTGTTGGTGGCTTAGTCCCAGCTGCAAT
AATGGCAATAGCGGCATCCAATTTACTAGTTAGAAATGTAATAAAAGAGGTAAATCCAAGCATTACACCCAAAGGGGAGA
CAACACTAGCTAAGTGGATATCAGCTGTTATAAAGTTCTTAGCTTTAGCCTTCGTGTTTCTAGTCCCATCTACATATGCC
ATCAACCTCCAATTGCTAGGAGGAATACTTATAACACAGACATTACCGGCAGTGTTCTTAGGTTTATACACTAAATGGTT
TAATCCATGGGCATTAACTGCGGGATGGGCTACTGGAATTATAAGCGGGACCTATATGTTCTTCACATTTGGACTACCTC
ATGCCACGTCTCTATATCCTACGCTTTTCGGTTTAATGTATGCTGCAGTAATAGCGTTAGTACTGAACCTGGTAGTTTCA
GTCATAGGTACGCTTGTAGCTAATGCCCTAGGGTTCAAGACTAAAAGCAATATATCTGCAGAGGATCTAAAAGGATGA

Upstream 100 bases:

>100_bases
GGAGTTTGCCGTTCTTCTATTGGTATCAAACAGTGTGGTTGGCAATATCAACAATACTTTTCTCAATAGCTGCGCTCCTT
CTTGCCAGAAGGTGATATAA

Downstream 100 bases:

>100_bases
AAGTTGAACTCAAACCTTTTTTATTTTAAAATCTTATTTACCTACTAGTAGTATATTCTAATTATGATATACGAGAAAGT
AGCTGAAGAACTTATTTCCT

Product: Na+/solute symporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MLGLAGIIVFIALFIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIAVPSSLYAKGAIYFF
AVPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRFNSSILAALIALTGVVAELPYIALQIVGMKSVLQMMLLGIGN
AALVSEISLIVSFIILAAFTYTSGLRGAALTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNL
QIAYWSLFLGSALALYLYPHSINGSLSADDKNRLMYSTALLPIYGIGLAIIALFGILVYAVPNALSVVSKYGGALVVPAL
ITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASNLLVRNVIKEVNPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYA
INLQLLGGILITQTLPAVFLGLYTKWFNPWALTAGWATGIISGTYMFFTFGLPHATSLYPTLFGLMYAAVIALVLNLVVS
VIGTLVANALGFKTKSNISAEDLKG

Sequences:

>Translated_505_residues
MLGLAGIIVFIALFIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIAVPSSLYAKGAIYFF
AVPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRFNSSILAALIALTGVVAELPYIALQIVGMKSVLQMMLLGIGN
AALVSEISLIVSFIILAAFTYTSGLRGAALTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNL
QIAYWSLFLGSALALYLYPHSINGSLSADDKNRLMYSTALLPIYGIGLAIIALFGILVYAVPNALSVVSKYGGALVVPAL
ITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASNLLVRNVIKEVNPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYA
INLQLLGGILITQTLPAVFLGLYTKWFNPWALTAGWATGIISGTYMFFTFGLPHATSLYPTLFGLMYAAVIALVLNLVVS
VIGTLVANALGFKTKSNISAEDLKG
>Mature_505_residues
MLGLAGIIVFIALFIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIAVPSSLYAKGAIYFF
AVPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRFNSSILAALIALTGVVAELPYIALQIVGMKSVLQMMLLGIGN
AALVSEISLIVSFIILAAFTYTSGLRGAALTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNL
QIAYWSLFLGSALALYLYPHSINGSLSADDKNRLMYSTALLPIYGIGLAIIALFGILVYAVPNALSVVSKYGGALVVPAL
ITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASNLLVRNVIKEVNPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYA
INLQLLGGILITQTLPAVFLGLYTKWFNPWALTAGWATGIISGTYMFFTFGLPHATSLYPTLFGLMYAAVIALVLNLVVS
VIGTLVANALGFKTKSNISAEDLKG

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54191; Mature: 54191

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]