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The map label for this gene is 227826589

Identifier: 227826589

GI number: 227826589

Start: 155738

End: 156793

Strand: Direct

Name: 227826589

Synonym: M1425_0179

Alternate gene names: NA

Gene position: 155738-156793 (Clockwise)

Preceding gene: 227826588

Following gene: 227826590

Centisome position: 5.97

GC content: 38.92

Gene sequence:

>1056_bases
ATGGTAACGAATTTACCCGCTGAAGCCAAGGCTAAATGGCTAAAGGTGATGGACGCAAAGACACCAGAGGAGAAATTCCA
AGCTTTGCAGGAATTTCTTAAGGAAGTTCCTAAACATAAGGGAACCGAAAATCTGGTATATTGGGCTAAGAGGCGAATGG
CAGAGTTAAGAGAAGAAATGGAGGTAAGAAAGAGCAAGAAAAGCGGAGGTTTTTCGTTATTTGTTGAGAAAGAGGGGGCG
GGTCAAGCGATTTTGATAGGAGATTTACTCCTAAGATCCTTAATAATGAAAAAACTTACCAACGTAAAACAAGAATTCAA
CGAGTTACCAGTGCCTGGCATGGTTAAATATGAGGATGTTCAAATACAGTTGGTTAACCCACCTAAGAGTCTTCCGCTCA
CTAAGACAATAGGTCTAATAAGGAATGCGGATGAGGTAATTATTGTTGTAAACAATAAGGAAGAACTATCCTTTATGAGG
AATATTTTGGAGGAGAATAATATCTTATTGAGAAAACCTAAGGGGAGGGTTATAATAGAGAGAACAAGGTATGGAATCTC
TGGAATTAGGATAGTAAATTTAGGTAAACTGGTGGACGTCGATGAAAAAGCCGTAAGGGATTATATAGAGAGTTTTGGGA
TTAAATCAGCAATAGTGAAGATCATAGGTGAGGTTGCCTTAGATGATATAGAGAAATCCATGTTCGAAGCAGTTAGCTAT
AAGCCTACAGTAGTAATCTCTAAGGAGAGGTTTGATACTGGCGAGTTACCAATATTGAGTATTGATCATTTAGATAAGTT
ACCTAAGCTTCTGTTTGAGATGTTAGAGGTGATCAGAATTTACACTAAGGAGCCTGGGGAAGAATCAACTAAGGATCCTT
TGATACTTAAAAAAGGTTCCACTGTTCTAGACGTAGCAAGGAAACTACATTCATCATTGGCTGAAAATTTTAGATATGCC
AGGGTTTGGGGAAGGTCGGTAAAGTTCCAGGGACAGAAAGTAGGCCCCTCACATGTTCTAGAAGATAAAGACATAGTTGA
GATCCATGCAAAGTGA

Upstream 100 bases:

>100_bases
ATGAGAAGAACCCAAATCCACCTCCCATTGTCAGAAGATCATGGAAAATTTTACGTTCTACTGCTCCACTATATTATATA
AGTAAAGAGGGTAGAAGACT

Downstream 100 bases:

>100_bases
GATTTTCTATATATAAGTTTAAGTATTAGTTTATAAGAAAGTAACAATAGTATGAGTATATTTAATAAGCGTAATAACAA
ACAAGCTGTTAACAATCAAG

Product: TGS domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEMEVRKSKKSGGFSLFVEKEGA
GQAILIGDLLLRSLIMKKLTNVKQEFNELPVPGMVKYEDVQIQLVNPPKSLPLTKTIGLIRNADEVIIVVNNKEELSFMR
NILEENNILLRKPKGRVIIERTRYGISGIRIVNLGKLVDVDEKAVRDYIESFGIKSAIVKIIGEVALDDIEKSMFEAVSY
KPTVVISKERFDTGELPILSIDHLDKLPKLLFEMLEVIRIYTKEPGEESTKDPLILKKGSTVLDVARKLHSSLAENFRYA
RVWGRSVKFQGQKVGPSHVLEDKDIVEIHAK

Sequences:

>Translated_351_residues
MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEMEVRKSKKSGGFSLFVEKEGA
GQAILIGDLLLRSLIMKKLTNVKQEFNELPVPGMVKYEDVQIQLVNPPKSLPLTKTIGLIRNADEVIIVVNNKEELSFMR
NILEENNILLRKPKGRVIIERTRYGISGIRIVNLGKLVDVDEKAVRDYIESFGIKSAIVKIIGEVALDDIEKSMFEAVSY
KPTVVISKERFDTGELPILSIDHLDKLPKLLFEMLEVIRIYTKEPGEESTKDPLILKKGSTVLDVARKLHSSLAENFRYA
RVWGRSVKFQGQKVGPSHVLEDKDIVEIHAK
>Mature_351_residues
MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEMEVRKSKKSGGFSLFVEKEGA
GQAILIGDLLLRSLIMKKLTNVKQEFNELPVPGMVKYEDVQIQLVNPPKSLPLTKTIGLIRNADEVIIVVNNKEELSFMR
NILEENNILLRKPKGRVIIERTRYGISGIRIVNLGKLVDVDEKAVRDYIESFGIKSAIVKIIGEVALDDIEKSMFEAVSY
KPTVVISKERFDTGELPILSIDHLDKLPKLLFEMLEVIRIYTKEPGEESTKDPLILKKGSTVLDVARKLHSSLAENFRYA
RVWGRSVKFQGQKVGPSHVLEDKDIVEIHAK

Specific function: Unknown

COG id: COG1163

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI4557537, Length=359, Percent_Identity=27.8551532033426, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4758796, Length=360, Percent_Identity=26.9444444444444, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71981008, Length=362, Percent_Identity=24.8618784530387, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17555344, Length=361, Percent_Identity=25.7617728531856, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319281, Length=369, Percent_Identity=28.4552845528455, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321612, Length=378, Percent_Identity=25.1322751322751, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356473, Length=360, Percent_Identity=27.5, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17981711, Length=361, Percent_Identity=28.2548476454294, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225
- InterPro:   IPR004095 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF02824 TGS [H]

EC number: NA

Molecular weight: Translated: 39943; Mature: 39943

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEM
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EVRKSKKSGGFSLFVEKEGAGQAILIGDLLLRSLIMKKLTNVKQEFNELPVPGMVKYEDV
HHHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECE
QIQLVNPPKSLPLTKTIGLIRNADEVIIVVNNKEELSFMRNILEENNILLRKPKGRVIIE
EEEEECCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCEEEE
RTRYGISGIRIVNLGKLVDVDEKAVRDYIESFGIKSAIVKIIGEVALDDIEKSMFEAVSY
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPTVVISKERFDTGELPILSIDHLDKLPKLLFEMLEVIRIYTKEPGEESTKDPLILKKGS
CCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
TVLDVARKLHSSLAENFRYARVWGRSVKFQGQKVGPSHVLEDKDIVEIHAK
HHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCCCCHHHCCCCCCEEEEECC
>Mature Secondary Structure
MVTNLPAEAKAKWLKVMDAKTPEEKFQALQEFLKEVPKHKGTENLVYWAKRRMAELREEM
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EVRKSKKSGGFSLFVEKEGAGQAILIGDLLLRSLIMKKLTNVKQEFNELPVPGMVKYEDV
HHHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECE
QIQLVNPPKSLPLTKTIGLIRNADEVIIVVNNKEELSFMRNILEENNILLRKPKGRVIIE
EEEEECCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCEEEE
RTRYGISGIRIVNLGKLVDVDEKAVRDYIESFGIKSAIVKIIGEVALDDIEKSMFEAVSY
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPTVVISKERFDTGELPILSIDHLDKLPKLLFEMLEVIRIYTKEPGEESTKDPLILKKGS
CCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
TVLDVARKLHSSLAENFRYARVWGRSVKFQGQKVGPSHVLEDKDIVEIHAK
HHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCCCCHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]