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The map label for this gene is dapA [H]

Identifier: 227826495

GI number: 227826495

Start: 72076

End: 72945

Strand: Direct

Name: dapA [H]

Synonym: M1425_0084

Alternate gene names: 227826495

Gene position: 72076-72945 (Clockwise)

Preceding gene: 227826492

Following gene: 227826496

Centisome position: 2.76

GC content: 33.79

Gene sequence:

>870_bases
GTGAAAGACAATATTTCCGCTCTTATTACACCCTTTGATGATAAAGAGAATATAAATGTCGAAGCATTACAGCAATTGTT
GGATTTTTTAACTAGAAGTGGGATTAAGGACTTTTGGGTTCTTGGAACTAGTGGAGAGTTTAATATGCTTTCTCAAGATG
AGAGAATATTAATCGTCAGTAAAATACGTGAAATTACAAAAGGCAAAATATACGCTGGTATTAATGAGAATTCACTCAAA
AATAGTCTAATATTGGCTAAAAAATACTATGATATTGGTGTTGATTATATTTTTTCAGTCCCACCTATTTATCATAAACC
TTCAGAAAAAGGGTTAGTAACCTATTTCAACGAGTTACGTAACAAGATAGATTTACCATTGTTCTTATACAACATACCCT
CATTTGCTGGGTATAATGTTCCTCTTCGTATAGTTGAGAAACTAGCGGAAGAGGAAGTATTAAATGGTATGAAATACTCA
ACTACAGATTTCGTCTCTTTCCTAAAGTATTTGAAGGGATTAAAAGGTGTAAATAAGAACTTTAAGGTATTCATTGGAGA
GGATAGGATGATCCTTTCTGCTCTTATCTATGACGCAGATGGTGCAGTTTCTGGGATCTCTAATTTAGTTCCAGAATTGG
TTACTAATTTATTCTTGGAATTTGATAGAGGTAATATTCAAAAGGCTATAGAGATTCAAAGAATGGTGAACAAATTAGTA
GATGTAGTAAGCTTAGGCGATTATCCAAGCGGGATTAAGATAGGTTTAAGGTATAGGGGGATTAACGTTGGCAGTGTTAG
GAAACCGTTAATGGAGGACAGTAGGGCTGAAGGGGAAATATATAATGCACTAAAAGAAATAGGTATATAG

Upstream 100 bases:

>100_bases
TATGGTAAGTAAGTATGAGAATTCTCTTCGTGATAAGTTAGACATCTGTGAAACAACTCTCAATAAAAATAAATAAAGTT
TTGTTTTAAATCATATAGTC

Downstream 100 bases:

>100_bases
GGATGATGAAGGTCGATGGGAAATACTGGATAATGAAGAGAATTATCCCCGGCTGAGAATTATGGATACCTTGGATCTTA
TTGCGGAAGAGGTAAGAAAA

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKDNISALITPFDDKENINVEALQQLLDFLTRSGIKDFWVLGTSGEFNMLSQDERILIVSKIREITKGKIYAGINENSLK
NSLILAKKYYDIGVDYIFSVPPIYHKPSEKGLVTYFNELRNKIDLPLFLYNIPSFAGYNVPLRIVEKLAEEEVLNGMKYS
TTDFVSFLKYLKGLKGVNKNFKVFIGEDRMILSALIYDADGAVSGISNLVPELVTNLFLEFDRGNIQKAIEIQRMVNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLMEDSRAEGEIYNALKEIGI

Sequences:

>Translated_289_residues
MKDNISALITPFDDKENINVEALQQLLDFLTRSGIKDFWVLGTSGEFNMLSQDERILIVSKIREITKGKIYAGINENSLK
NSLILAKKYYDIGVDYIFSVPPIYHKPSEKGLVTYFNELRNKIDLPLFLYNIPSFAGYNVPLRIVEKLAEEEVLNGMKYS
TTDFVSFLKYLKGLKGVNKNFKVFIGEDRMILSALIYDADGAVSGISNLVPELVTNLFLEFDRGNIQKAIEIQRMVNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLMEDSRAEGEIYNALKEIGI
>Mature_289_residues
MKDNISALITPFDDKENINVEALQQLLDFLTRSGIKDFWVLGTSGEFNMLSQDERILIVSKIREITKGKIYAGINENSLK
NSLILAKKYYDIGVDYIFSVPPIYHKPSEKGLVTYFNELRNKIDLPLFLYNIPSFAGYNVPLRIVEKLAEEEVLNGMKYS
TTDFVSFLKYLKGLKGVNKNFKVFIGEDRMILSALIYDADGAVSGISNLVPELVTNLFLEFDRGNIQKAIEIQRMVNKLV
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLMEDSRAEGEIYNALKEIGI

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=286, Percent_Identity=29.3706293706294, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI31543060, Length=277, Percent_Identity=25.2707581227437, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI87082415, Length=295, Percent_Identity=26.4406779661017, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=26.4604810996564, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786463, Length=229, Percent_Identity=27.9475982532751, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789620, Length=276, Percent_Identity=25.3623188405797, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32639; Mature: 32639

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNISALITPFDDKENINVEALQQLLDFLTRSGIKDFWVLGTSGEFNMLSQDERILIVS
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEHHH
KIREITKGKIYAGINENSLKNSLILAKKYYDIGVDYIFSVPPIYHKPSEKGLVTYFNELR
HHHHHHCCCEEECCCCCCHHHHEEEEHHHHHCCCHHEECCCCCCCCCCCCCHHHHHHHHH
NKIDLPLFLYNIPSFAGYNVPLRIVEKLAEEEVLNGMKYSTTDFVSFLKYLKGLKGVNKN
HHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
FKVFIGEDRMILSALIYDADGAVSGISNLVPELVTNLFLEFDRGNIQKAIEIQRMVNKLV
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLMEDSRAEGEIYNALKEIGI
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKDNISALITPFDDKENINVEALQQLLDFLTRSGIKDFWVLGTSGEFNMLSQDERILIVS
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEHHH
KIREITKGKIYAGINENSLKNSLILAKKYYDIGVDYIFSVPPIYHKPSEKGLVTYFNELR
HHHHHHCCCEEECCCCCCHHHHEEEEHHHHHCCCHHEECCCCCCCCCCCCCHHHHHHHHH
NKIDLPLFLYNIPSFAGYNVPLRIVEKLAEEEVLNGMKYSTTDFVSFLKYLKGLKGVNKN
HHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
FKVFIGEDRMILSALIYDADGAVSGISNLVPELVTNLFLEFDRGNIQKAIEIQRMVNKLV
CEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DVVSLGDYPSGIKIGLRYRGINVGSVRKPLMEDSRAEGEIYNALKEIGI
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]