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The map label for this gene is yyaL [H]

Identifier: 227826432

GI number: 227826432

Start: 18762

End: 20693

Strand: Direct

Name: yyaL [H]

Synonym: M1425_0021

Alternate gene names: 227826432

Gene position: 18762-20693 (Clockwise)

Preceding gene: 227826431

Following gene: 227826433

Centisome position: 0.72

GC content: 36.02

Gene sequence:

>1932_bases
ATGAATGAGAGATTAAGGAATTCTCAAAGTGGTTATTTGAGGAAAGCGGTAAATCATCCAATAAATTGGTATACCTGGTC
TAACGAAATATTTGAAATTGCGAAAAGCGAGGATAAGCCGATACTTATTGATGTAGGTGCTGCTTGGTGCCATTGGTGTA
ACGTTATGGATGAAGATACCTATTCAAACCCAGAAATAGTTAAGATAGTTAATGAAAATTTCATTCCAGTTAAGGTTGAT
CGAGATGAAATGCCCGATCTGGATAGACTTCTACAAAACGCAGCCATGACCATAACAGGTGAGTCTGGGTGGCCTTTAAC
CATATTCATGACACCCGAGGGAAAGGTCTTCTTTGGTGGAACTTACTTTCCTCCAGAAGATAAGTATGGAAGAATAGGCT
TTAAGAAATTATTGTTAGAGATTTTGAGAATATGGAGAGAAGACAGAAACCAAATATTCTCATCTTCAATAGACCCTAAT
ATGCTAATTGCTAGGAATACTGGTGGAGTTCTAAGTTCAAGTGTTCTAGATGACGCGTTTTCCTATATAACATCCTATTT
TGACATTGAGTATGGTGGATTAGGATTTGGCGCTAAATTTCCCCATCCTTTTGTGGATTTACTATTCCTCAACTACAGTG
CTACTAGAGGAGATGACTTAGGTAAAAAACTTGGTCTATTCACCTTAAGGAAAATGTATTATGGCGGGATTTTTGATCAA
GTTGGTGGAGGATTTCATAGATATACTGTTGATAGAGAATGGAAGTTACCTCATTTTGAGAAACTACTTATAGATAATGC
CGAATTGATTTACGATTATTTTACTTATTATACGGCAACTAATGACATAGAAATTCTTGATGCCTTAAGAAATTCAGTAG
ATTTTGTTTTAAGAGAACTATACATGGATGGGAAAGGTTTTGCTAATAGCTTAGATGCAGATAGTGAAGGTATGGAGGGT
AAGTACTATACGTGGACTGAGGATGAGCTTAAAGGTGCTTTAGGAAATGATTATGGTATTGCGATAAGGGTATTCGACCT
AAAGAATACTGTAGAAGTTGAGGGCAGGAAAGTTCTATTGAGAACAACTGAACTTAGGGAGCTATCTAAGGTAACAGGTT
TACAAGCAAATGAGATAATAGAGAAGGTAAGTGAGATAAGGGCCAAACTATTGACGTATAGAGAGCAAAATAGGAAAATG
CCATATAGAGATGATAGTACATACACTTATCCTAACGCAAAGCTTACTGAATCTATACTGTTTTCCTCATTAATTTTAAA
CAAGGGTATTGAGGAGGCTAAGCTTGTTCTGAGTAAGTTAGGAAAAAGTGTTAGCAGGAGGTTAGATGGTGGAAAAGCTG
GATTACCAGAAGATTATGCTGCAGCACTTTTAGCAAGTATCTCCGCATACGAGGTATTAAGTGAAGAAAAGTATTATGAT
TTGGCAATTGAACTCGGTAGAAACATTGGAGGTATTAGGCCTAATAATTTCACTGACATGCCTAATGAGTCTGCAAATTC
AATGTATATTAGGGCGTTATTCAAATTATCTCTATTATCTGATGAGTTTAAAGTTGATGAAGGGAAAATTAAACCTCTAA
TTCCCTCTCTAACCGCTGAAAATTCTCAATTTATTGCTGGGATAGTTAATACTATCTCGAGTTACATTAATGGTATGGCT
CATATCGTAGTGGTTGATGAAAAGGACGGACTAGCTGAAAGACTGCATAGAACTGCGTTACTTACCTATTATCCCTTTAA
ATTAATTGAAAGGGTAGATGACAGTAGAACTGATTACGTTAGTTCAGTAATAAGGGCTATGATAAAATATAATGCGGGAA
AGAGTAGAGCATATGTTTGTATAGGCAATACGTGTAGTATGCCAGTAAGTGAAGAGGAAAAGATTAAACAATTACTTAAA
ACTAAGCTTTAA

Upstream 100 bases:

>100_bases
TAGGATTTTTCGTATTATATAAAATATATTCTAGAAAAGACCAAGATACTAATGTTTGATAACAAATTTTAAATGTGAAC
TCGTTACTAAAAATATTAGA

Downstream 100 bases:

>100_bases
CATTTTTATGTATGGGAAGGTTAGACAATAAGAAAGTAGCTATTATAGGTGTAAGCGAGGGTTTAGGTTACGCCACTGCC
TATTTCGCATTAAAAGAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MNERLRNSQSGYLRKAVNHPINWYTWSNEIFEIAKSEDKPILIDVGAAWCHWCNVMDEDTYSNPEIVKIVNENFIPVKVD
RDEMPDLDRLLQNAAMTITGESGWPLTIFMTPEGKVFFGGTYFPPEDKYGRIGFKKLLLEILRIWREDRNQIFSSSIDPN
MLIARNTGGVLSSSVLDDAFSYITSYFDIEYGGLGFGAKFPHPFVDLLFLNYSATRGDDLGKKLGLFTLRKMYYGGIFDQ
VGGGFHRYTVDREWKLPHFEKLLIDNAELIYDYFTYYTATNDIEILDALRNSVDFVLRELYMDGKGFANSLDADSEGMEG
KYYTWTEDELKGALGNDYGIAIRVFDLKNTVEVEGRKVLLRTTELRELSKVTGLQANEIIEKVSEIRAKLLTYREQNRKM
PYRDDSTYTYPNAKLTESILFSSLILNKGIEEAKLVLSKLGKSVSRRLDGGKAGLPEDYAAALLASISAYEVLSEEKYYD
LAIELGRNIGGIRPNNFTDMPNESANSMYIRALFKLSLLSDEFKVDEGKIKPLIPSLTAENSQFIAGIVNTISSYINGMA
HIVVVDEKDGLAERLHRTALLTYYPFKLIERVDDSRTDYVSSVIRAMIKYNAGKSRAYVCIGNTCSMPVSEEEKIKQLLK
TKL

Sequences:

>Translated_643_residues
MNERLRNSQSGYLRKAVNHPINWYTWSNEIFEIAKSEDKPILIDVGAAWCHWCNVMDEDTYSNPEIVKIVNENFIPVKVD
RDEMPDLDRLLQNAAMTITGESGWPLTIFMTPEGKVFFGGTYFPPEDKYGRIGFKKLLLEILRIWREDRNQIFSSSIDPN
MLIARNTGGVLSSSVLDDAFSYITSYFDIEYGGLGFGAKFPHPFVDLLFLNYSATRGDDLGKKLGLFTLRKMYYGGIFDQ
VGGGFHRYTVDREWKLPHFEKLLIDNAELIYDYFTYYTATNDIEILDALRNSVDFVLRELYMDGKGFANSLDADSEGMEG
KYYTWTEDELKGALGNDYGIAIRVFDLKNTVEVEGRKVLLRTTELRELSKVTGLQANEIIEKVSEIRAKLLTYREQNRKM
PYRDDSTYTYPNAKLTESILFSSLILNKGIEEAKLVLSKLGKSVSRRLDGGKAGLPEDYAAALLASISAYEVLSEEKYYD
LAIELGRNIGGIRPNNFTDMPNESANSMYIRALFKLSLLSDEFKVDEGKIKPLIPSLTAENSQFIAGIVNTISSYINGMA
HIVVVDEKDGLAERLHRTALLTYYPFKLIERVDDSRTDYVSSVIRAMIKYNAGKSRAYVCIGNTCSMPVSEEEKIKQLLK
TKL
>Mature_643_residues
MNERLRNSQSGYLRKAVNHPINWYTWSNEIFEIAKSEDKPILIDVGAAWCHWCNVMDEDTYSNPEIVKIVNENFIPVKVD
RDEMPDLDRLLQNAAMTITGESGWPLTIFMTPEGKVFFGGTYFPPEDKYGRIGFKKLLLEILRIWREDRNQIFSSSIDPN
MLIARNTGGVLSSSVLDDAFSYITSYFDIEYGGLGFGAKFPHPFVDLLFLNYSATRGDDLGKKLGLFTLRKMYYGGIFDQ
VGGGFHRYTVDREWKLPHFEKLLIDNAELIYDYFTYYTATNDIEILDALRNSVDFVLRELYMDGKGFANSLDADSEGMEG
KYYTWTEDELKGALGNDYGIAIRVFDLKNTVEVEGRKVLLRTTELRELSKVTGLQANEIIEKVSEIRAKLLTYREQNRKM
PYRDDSTYTYPNAKLTESILFSSLILNKGIEEAKLVLSKLGKSVSRRLDGGKAGLPEDYAAALLASISAYEVLSEEKYYD
LAIELGRNIGGIRPNNFTDMPNESANSMYIRALFKLSLLSDEFKVDEGKIKPLIPSLTAENSQFIAGIVNTISSYINGMA
HIVVVDEKDGLAERLHRTALLTYYPFKLIERVDDSRTDYVSSVIRAMIKYNAGKSRAYVCIGNTCSMPVSEEEKIKQLLK
TKL

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=727, Percent_Identity=27.5103163686382, Blast_Score=272, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI25147430, Length=535, Percent_Identity=31.7757009345794, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI20129985, Length=349, Percent_Identity=34.0974212034384, Blast_Score=221, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: NA

Molecular weight: Translated: 73079; Mature: 73079

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERLRNSQSGYLRKAVNHPINWYTWSNEIFEIAKSEDKPILIDVGAAWCHWCNVMDEDT
CCCHHCCCCCHHHHHHHCCCCEEEECCHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCC
YSNPEIVKIVNENFIPVKVDRDEMPDLDRLLQNAAMTITGESGWPLTIFMTPEGKVFFGG
CCCCCEEEEECCCEEEEEECCCCCCCHHHHHHCCEEEEECCCCCEEEEEECCCCCEEECC
TYFPPEDKYGRIGFKKLLLEILRIWREDRNQIFSSSIDPNMLIARNTGGVLSSSVLDDAF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
SYITSYFDIEYGGLGFGAKFPHPFVDLLFLNYSATRGDDLGKKLGLFTLRKMYYGGIFDQ
HHHHHHHCCEECCCCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCHHH
VGGGFHRYTVDREWKLPHFEKLLIDNAELIYDYFTYYTATNDIEILDALRNSVDFVLREL
HCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YMDGKGFANSLDADSEGMEGKYYTWTEDELKGALGNDYGIAIRVFDLKNTVEVEGRKVLL
HHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEEEEEEECCCCEEECCCEEEE
RTTELRELSKVTGLQANEIIEKVSEIRAKLLTYREQNRKMPYRDDSTYTYPNAKLTESIL
EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHH
FSSLILNKGIEEAKLVLSKLGKSVSRRLDGGKAGLPEDYAAALLASISAYEVLSEEKYYD
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
LAIELGRNIGGIRPNNFTDMPNESANSMYIRALFKLSLLSDEFKVDEGKIKPLIPSLTAE
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSQFIAGIVNTISSYINGMAHIVVVDEKDGLAERLHRTALLTYYPFKLIERVDDSRTDYV
CCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SSVIRAMIKYNAGKSRAYVCIGNTCSMPVSEEEKIKQLLKTKL
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNERLRNSQSGYLRKAVNHPINWYTWSNEIFEIAKSEDKPILIDVGAAWCHWCNVMDEDT
CCCHHCCCCCHHHHHHHCCCCEEEECCHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCC
YSNPEIVKIVNENFIPVKVDRDEMPDLDRLLQNAAMTITGESGWPLTIFMTPEGKVFFGG
CCCCCEEEEECCCEEEEEECCCCCCCHHHHHHCCEEEEECCCCCEEEEEECCCCCEEECC
TYFPPEDKYGRIGFKKLLLEILRIWREDRNQIFSSSIDPNMLIARNTGGVLSSSVLDDAF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
SYITSYFDIEYGGLGFGAKFPHPFVDLLFLNYSATRGDDLGKKLGLFTLRKMYYGGIFDQ
HHHHHHHCCEECCCCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCHHH
VGGGFHRYTVDREWKLPHFEKLLIDNAELIYDYFTYYTATNDIEILDALRNSVDFVLREL
HCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YMDGKGFANSLDADSEGMEGKYYTWTEDELKGALGNDYGIAIRVFDLKNTVEVEGRKVLL
HHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEEEEEEECCCCEEECCCEEEE
RTTELRELSKVTGLQANEIIEKVSEIRAKLLTYREQNRKMPYRDDSTYTYPNAKLTESIL
EHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHH
FSSLILNKGIEEAKLVLSKLGKSVSRRLDGGKAGLPEDYAAALLASISAYEVLSEEKYYD
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
LAIELGRNIGGIRPNNFTDMPNESANSMYIRALFKLSLLSDEFKVDEGKIKPLIPSLTAE
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSQFIAGIVNTISSYINGMAHIVVVDEKDGLAERLHRTALLTYYPFKLIERVDDSRTDYV
CCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SSVIRAMIKYNAGKSRAYVCIGNTCSMPVSEEEKIKQLLKTKL
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]