Click here to switch to the map view.

The map label for this gene is uvsE [H]

Identifier: 227818110

GI number: 227818110

Start: 5079729

End: 5080682

Strand: Direct

Name: uvsE [H]

Synonym: BAMEG_5636

Alternate gene names: 227818110

Gene position: 5079729-5080682 (Clockwise)

Preceding gene: 227818109

Following gene: 227818111

Centisome position: 97.12

GC content: 34.17

Gene sequence:

>954_bases
ATGATTATGCGGTTCGGATATGTCTCACATGCAATGGCACTCTGGGACTGCTCTCCGGCTAAAACGATAACATTTACAAG
CTTTCAAAAGCTCAGTAAACAAGAGCGAGAAGATAAATTATACGATGTTACAAAACAAAATCTTGAGCATACAATACGTA
TTCTCCATTACAATATAGCTCATGAAATTCCGTTATATCGCTTGTCTTCTTCCATCGTCCCACTTGCAACACATCCCGAA
GTCGAGTTTGATTATATCGGGGCATTTACACCGCTTTGGCGTAAAATTGGGGCATTAATTAAAGAACATAATTTAAGAAT
AAGTTTTCATCCAAATCAATTTACACTATTTACAAGCGACAAACCACATATTACGACTAACGCTATTACAGATATGACCT
ATCATTATAAAGTATTAGATGCAATAGGCATTGCAGATTCTTCTTATATTAACATCCATGTAGGTGGGGCCTACGGAAAT
AAAGAAAAAGCAATCGAGCGTTTCCATGAAAACATAAAAAAACTTCCTGCACATATAAAAAAGCAAATGACACTTGAAAA
TGATGATAAAACATATACAACAGCTGAAACGTTATCTATTTGCCAAAAAGAAAAGATCCCATTCGTATTTGATTATCACC
ATCACATGGCAAATCTTTGCGAGGAACCGTTAGAAGAGTTGCTTCCTGCAATTTTTGAAACTTGGTCACATACAAATATC
GTTCCTAAAGTTCACATTTCCTCTCCTAAATCAAAAAAAGAATTTAGGGCTCACGCGGAATATATTGATTTAGAATTTAT
TAAACCTTTCTTACACGTTGCAAAAAAAATCAATCATAATTTCGATATTATGATTGAAAGTAAACAGAAAGATTTAGCGA
TGCTGCAATTCATACAGGAATTATCCTCTATAAGAGGGATAAAAAGAATAAGTAGCTCAACATTACAATGGTAA

Upstream 100 bases:

>100_bases
TTAGCCCGCATTCTCTTATTGATAGAGGAAAAGAATGGATAGGAACAATACTCGCTTTCTTCCTATAGGAAAGATAATGC
ATAAAGGATGTGTATTCATT

Downstream 100 bases:

>100_bases
ATTGTAATGTTGAGCTATTTTTTTCAAAAAAAGTAATTTTTTAGTAAAAAACACCCTATTTTATATGCTATGATTGGAAT
TAGCATTTTCCACCTGTGAT

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPE
VEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGN
KEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNI
VPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISSSTLQW

Sequences:

>Translated_317_residues
MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPE
VEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGN
KEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNI
VPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISSSTLQW
>Mature_317_residues
MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPE
VEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGN
KEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNI
VPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISSSTLQW

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 36879; Mature: 36879

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIA
CEEEECHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
HEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSD
HCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCCEEEEEECC
KPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENIKKLPAHIK
CCCEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
KQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNI
HHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LSSIRGIKRISSSTLQW
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIA
CEEEECHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
HEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSD
HCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCCEEEEEECC
KPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENIKKLPAHIK
CCCEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
KQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNI
HHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LSSIRGIKRISSSTLQW
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA