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The map label for this gene is moaA [H]

Identifier: 227817517

GI number: 227817517

Start: 4518414

End: 4519040

Strand: Reverse

Name: moaA [H]

Synonym: BAMEG_5009

Alternate gene names: 227817517

Gene position: 4519040-4518414 (Counterclockwise)

Preceding gene: 227817518

Following gene: 227817516

Centisome position: 86.4

GC content: 38.76

Gene sequence:

>627_bases
ATGCCAGCGGAAGTGTTTGGGCCAGATTATGCTTTTTTGAAAGATGAGTTTTTACTGACGTTTGATGAAATTGAGCGTGT
AGCAAAACTATTTGTTAGCATCGGTGTACGAAAAATTAGACTTACTGGTGGCGAGCCACTACTTCGTAAAGATTTAGCAA
AACTTATTGCACGTCTCGTGAAAATTGACGGGCTATTAGATATAGGGTTAACGACCAATGCAATTCATTTAACAAAGCAA
GCGAAAGTATTAAAAGAAGCTGGATTACATAGAGTAAATGTTAGCTTGGATGCAATAGATGATGATGTATTTAAGGCTAT
TAATGGCCGGAATATTAATACGAAACCTGTTATAAAGGGGATTATGGCTGCAAAAGAAGCCGGACTTGATGTAAAGGTAA
ACATGGTTGTGAAAAAAGGGATGAACGATCATCAAGTACTTCCGATGGCTGCGTATTTTAAAGAGCAAGGAATCCCACTT
AGGTTCATTGAGTTTATGGATGTTGGTAGTACAAATGGATGGAACTTTGATCAAGTTGTTACGAAGCGAGAGTTAATTGA
GATGATTCATCGCGTGTATCCGCTTGAGCCAGCTGAAGCGCATTATTTTGGTGAAGTTGCGAAGTGA

Upstream 100 bases:

>100_bases
GTGGCGATGCAGGAGATGGTTACAGATTTTTTTTGGACGCCCACTTCAAGATTTACGCATATCTGTCATTGATCGTTGCA
ATTTTAGATGTACATATTGT

Downstream 100 bases:

>100_bases
TATCGTTACGTTGGAACAAATGTTGAAGTCGGTTTTATTACTTCTGTGTCTGAGTCATTTTGTTCTTCTTGTACGAGAGC
GAGAATTTCGGCAGATGGAA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPAEVFGPDYAFLKDEFLLTFDEIERVAKLFVSIGVRKIRLTGGEPLLRKDLAKLIARLVKIDGLLDIGLTTNAIHLTKQ
AKVLKEAGLHRVNVSLDAIDDDVFKAINGRNINTKPVIKGIMAAKEAGLDVKVNMVVKKGMNDHQVLPMAAYFKEQGIPL
RFIEFMDVGSTNGWNFDQVVTKRELIEMIHRVYPLEPAEAHYFGEVAK

Sequences:

>Translated_208_residues
MPAEVFGPDYAFLKDEFLLTFDEIERVAKLFVSIGVRKIRLTGGEPLLRKDLAKLIARLVKIDGLLDIGLTTNAIHLTKQ
AKVLKEAGLHRVNVSLDAIDDDVFKAINGRNINTKPVIKGIMAAKEAGLDVKVNMVVKKGMNDHQVLPMAAYFKEQGIPL
RFIEFMDVGSTNGWNFDQVVTKRELIEMIHRVYPLEPAEAHYFGEVAK
>Mature_207_residues
PAEVFGPDYAFLKDEFLLTFDEIERVAKLFVSIGVRKIRLTGGEPLLRKDLAKLIARLVKIDGLLDIGLTTNAIHLTKQA
KVLKEAGLHRVNVSLDAIDDDVFKAINGRNINTKPVIKGIMAAKEAGLDVKVNMVVKKGMNDHQVLPMAAYFKEQGIPLR
FIEFMDVGSTNGWNFDQVVTKRELIEMIHRVYPLEPAEAHYFGEVAK

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=180, Percent_Identity=42.7777777777778, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI22027536, Length=180, Percent_Identity=42.7777777777778, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1786999, Length=153, Percent_Identity=41.8300653594771, Blast_Score=116, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566331, Length=172, Percent_Identity=35.4651162790698, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566329, Length=172, Percent_Identity=35.4651162790698, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17561210, Length=172, Percent_Identity=35.4651162790698, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574488, Length=177, Percent_Identity=36.7231638418079, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574490, Length=177, Percent_Identity=36.7231638418079, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 23301; Mature: 23169

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEVFGPDYAFLKDEFLLTFDEIERVAKLFVSIGVRKIRLTGGEPLLRKDLAKLIARLV
CCCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHH
KIDGLLDIGLTTNAIHLTKQAKVLKEAGLHRVNVSLDAIDDDVFKAINGRNINTKPVIKG
HHCCEEECCCCCCEEEHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHH
IMAAKEAGLDVKVNMVVKKGMNDHQVLPMAAYFKEQGIPLRFIEFMDVGSTNGWNFDQVV
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHH
TKRELIEMIHRVYPLEPAEAHYFGEVAK
HHHHHHHHHHHHCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
PAEVFGPDYAFLKDEFLLTFDEIERVAKLFVSIGVRKIRLTGGEPLLRKDLAKLIARLV
CCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHH
KIDGLLDIGLTTNAIHLTKQAKVLKEAGLHRVNVSLDAIDDDVFKAINGRNINTKPVIKG
HHCCEEECCCCCCEEEHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHH
IMAAKEAGLDVKVNMVVKKGMNDHQVLPMAAYFKEQGIPLRFIEFMDVGSTNGWNFDQVV
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHH
TKRELIEMIHRVYPLEPAEAHYFGEVAK
HHHHHHHHHHHHCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA