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The map label for this gene is infC

Identifier: 227817359

GI number: 227817359

Start: 4382205

End: 4382708

Strand: Reverse

Name: infC

Synonym: BAMEG_4849

Alternate gene names: 227817359

Gene position: 4382708-4382205 (Counterclockwise)

Preceding gene: 227817360

Following gene: 227817358

Centisome position: 83.8

GC content: 38.29

Gene sequence:

>504_bases
ATGATGATTAACGAGCAAATTCGTGCACGTGAAGTACGTTTAGTTGGCGCAAATGGCGATCAACTTGGAATCAAGTCTCG
TAATGACGCTTTAGACTTAGCTGCAAATCTTAATCTTGATTTAGTATTAGTTGCTCCAAATGCGAAACCGCCAGTATGCC
GCATTATGGACTACGGTAAATTCCGCTTTGAGCAACAGAAGAAAGAAAAAGAACAGCGCAAAAATCAAAAAGTAATTAGC
ATGAAAGAAGTTCGTTTAAGTCCAACAATTGATGAACACGACTTTAACACAAAACTTCGTAATGCTATCAAGTTTTTAGA
GAAAGGCGACAAGGTTAAAGCGTCAATTCGCTTTAAAGGACGTGCCATTACTCATAAAGAAATCGGTCAACGTGTTTTAG
ATCGCTTCTCAGAAGCTTGTGCTGAAGTTAGTACAATCGAATCTAAGCCTAAAATGGAAGGACGCAGTATGTTCTTAGTT
TTAGCACCGAAAAACGATAAGTAA

Upstream 100 bases:

>100_bases
CAAGTGTGGGTGTCGTATGCCCGCACTTTTTTTGTCGGGTTCTATGACTACAAACTATGTTCTGAGAAAACCTTGGAGGT
GGCTTACTATTAGCAAGGAT

Downstream 100 bases:

>100_bases
TAGATAGAGGAGGAAATACCTATGCCTAAACAAAAAACTCATCGCGGCGCTGCAAAGCGTTTCAAAAAGACTGGATCAGG
TAAACTGAAACGTTCTCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVIS
MKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLV
LAPKNDK

Sequences:

>Translated_167_residues
MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVIS
MKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLV
LAPKNDK
>Mature_167_residues
MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVIS
MKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLV
LAPKNDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=53.9877300613497, Blast_Score=166, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BACAN (Q81L15)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847022.1
- RefSeq:   YP_021465.2
- RefSeq:   YP_030718.1
- ProteinModelPortal:   Q81L15
- IntAct:   Q81L15
- EnsemblBacteria:   EBBACT00000012731
- EnsemblBacteria:   EBBACT00000018781
- EnsemblBacteria:   EBBACT00000023613
- GeneID:   1083958
- GeneID:   2815793
- GeneID:   2851577
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4819
- KEGG:   bar:GBAA_4819
- KEGG:   bat:BAS4471
- TIGR:   BA_4819
- TIGR:   GBAA_4819
- GeneTree:   EBGT00050000001839
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   BANT260799:BAS4471-MONOMER
- BioCyc:   BANT261594:GBAA4819-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19081; Mature: 19081

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGK
CCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCH
FRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKG
HHHHHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
RAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGK
CCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCH
FRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKG
HHHHHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
RAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629