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The map label for this gene is lon [H]

Identifier: 227817251

GI number: 227817251

Start: 4279797

End: 4280492

Strand: Reverse

Name: lon [H]

Synonym: BAMEG_4738

Alternate gene names: 227817251

Gene position: 4280492-4279797 (Counterclockwise)

Preceding gene: 227817252

Following gene: 227817250

Centisome position: 81.84

GC content: 35.78

Gene sequence:

>696_bases
ATGTCTAGTATGAATACGAATGAAAGAATCGTACCCCTCCTACCATTAAGAGGCGTTCTCGTATATCCAACGATGGTTCT
GCATCTTGATGTAGGACGTGATAAATCGATACAAGCACTAGAGCAGGCGGCAATGGATGAAAATATCATCTTTTTAGCAA
TGCAAAAAGAAATGAATATCGATGATCCGAAAGAAGATGACATATATAGTGTAGGTACAGTGGCGAAAGTGAAGCAAATG
TTAAAATTGCCGAACGGTACGCTTCGTGTCCTTGTAGAAGGTTTACATAGAGCAGAAGTAGTAGAGTTTATCGAAGAAGA
AAATGTAGTGCAAGTTTCTATTAAAACGGTAACTGAAGAAGTGGAAGCTGATTTAGAAGAGAAAGCACTTATGCGTACAT
TACTGGAGCATTTCGAACAATATATTAAAGTTTCGAAAAAAGTTTCAAATGAAACATTTGCAACGGTAGCTGATGTAGAA
GAGCCAGGAAGATTAGTGGATTTAATTGCTTCTCACTTGCCAATTAAAACGAAGCAGAAACAAGAGATTTTAGAAATCAT
ATCTGTGAAAGAACGATTACATACACTTATTTCAATTATTCAAGATGAACAAGAATTACTTAGTTTAGAAAAGAAAATTG
GACAAAAAGTGAAACGTTCAATGGAGCGCACGCAAAAAAGAATATTTCTTGCGTGA

Upstream 100 bases:

>100_bases
AAAAGCGGGATTTACAGTTGCGGAGAATCTCGGCAATTGCATCTAGATGTATTGTAATATAAAATGGTTGAACAGGAGTT
TAATTTATTATGGAGGTGCT

Downstream 100 bases:

>100_bases
GCAAATGAAGGCGATTCAAACTGAACTTGGCGATAAAGAAGGCAAGGGCGGGGAAGTTGAAGAACTTCGTGAGAAAATTG
AACAGTCAGGAATGCCTGAA

Product: ATP-dependent protease La 1

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQM
LKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVE
EPGRLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKRIFLA

Sequences:

>Translated_231_residues
MSSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQM
LKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVE
EPGRLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKRIFLA
>Mature_230_residues
SSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNIDDPKEDDIYSVGTVAKVKQML
KLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEEVEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEE
PGRLVDLIASHLPIKTKQKQEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKRIFLA

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG0466

COG function: function code O; ATP-dependent Lon protease, bacterial type

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Escherichia coli, GI1786643, Length=226, Percent_Identity=43.3628318584071, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 26384; Mature: 26253

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNI
CCCCCCCCCEEEECCCCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCC
DDPKEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEE
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
VEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLVDLIASHLPIKTKQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
QEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKRIFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSMNTNERIVPLLPLRGVLVYPTMVLHLDVGRDKSIQALEQAAMDENIIFLAMQKEMNI
CCCCCCCCEEEECCCCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCC
DDPKEDDIYSVGTVAKVKQMLKLPNGTLRVLVEGLHRAEVVEFIEEENVVQVSIKTVTEE
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
VEADLEEKALMRTLLEHFEQYIKVSKKVSNETFATVADVEEPGRLVDLIASHLPIKTKQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
QEILEIISVKERLHTLISIIQDEQELLSLEKKIGQKVKRSMERTQKRIFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA