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The map label for this gene is mutT [C]

Identifier: 227816586

GI number: 227816586

Start: 3698358

End: 3698819

Strand: Reverse

Name: mutT [C]

Synonym: BAMEG_4044

Alternate gene names: 227816586

Gene position: 3698819-3698358 (Counterclockwise)

Preceding gene: 227816587

Following gene: 227816585

Centisome position: 70.72

GC content: 37.88

Gene sequence:

>462_bases
GTGGAACATAAAACACCAAAGCATATTGTTGCTGTAGCAGGCTATTTAACAAATGAAAAAGATGAAGTGTTATTAGCAAA
GGTACACTGGCGAGCTGATACGTGGGAGTTGCCAGGAGGACAGGTAGAAGAAGGGGAAGCACTCGATCAAGCTGTTTGTA
GGGAAATAAAAGAGGAAACAGGATTAACGGTGAAGCCTATCGGTATTACAGGAGTTTATTATAATGCTTCCATGAACATT
TTAGCTGTCGTTTTTAAAGTAGCATATGTAAGCGGTGAAATAAAAATTCAACATGAAGAAATACAAGAGGCTAAATTTGT
TGCTTTAAATGAAGAGAACATAGATGAGTATATAACGCGTCCTCATATGAAATCCAGAACGCTGGATGCGATGAGGTCAT
CACATTTTATTCCTTATGAAACGTGGGAAGTACAGCCGTATAACTTAATAGGAAGATTGTAA

Upstream 100 bases:

>100_bases
GGTAATTAAGGCAATGAATTTAATAAAGGTATTTTGTTGTAAACAGGGAATATGCTTATAGGGATATATGGAATACTCAT
TATTGCTAGGAGGCTTACAT

Downstream 100 bases:

>100_bases
AGAAAAGAGTAGCCGATTTGAGATACAGTCAAATCACTACTCTTTTTTGTATACTGTTTAAGAAAAAGGTCAAAATAATA
GTAGTGTTAGTATTGATTTT

Product: mutT/nudix family protein

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT-Like Protein; ADP-Ribose Pyrophosphatase; MutT/Nudix Family Protein; MutT/NUDIX Family Protein; NUDIX Family Hydrolase; Hydrolase

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MEHKTPKHIVAVAGYLTNEKDEVLLAKVHWRADTWELPGGQVEEGEALDQAVCREIKEETGLTVKPIGITGVYYNASMNI
LAVVFKVAYVSGEIKIQHEEIQEAKFVALNEENIDEYITRPHMKSRTLDAMRSSHFIPYETWEVQPYNLIGRL

Sequences:

>Translated_153_residues
MEHKTPKHIVAVAGYLTNEKDEVLLAKVHWRADTWELPGGQVEEGEALDQAVCREIKEETGLTVKPIGITGVYYNASMNI
LAVVFKVAYVSGEIKIQHEEIQEAKFVALNEENIDEYITRPHMKSRTLDAMRSSHFIPYETWEVQPYNLIGRL
>Mature_153_residues
MEHKTPKHIVAVAGYLTNEKDEVLLAKVHWRADTWELPGGQVEEGEALDQAVCREIKEETGLTVKPIGITGVYYNASMNI
LAVVFKVAYVSGEIKIQHEEIQEAKFVALNEENIDEYITRPHMKSRTLDAMRSSHFIPYETWEVQPYNLIGRL

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17469; Mature: 17469

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKTPKHIVAVAGYLTNEKDEVLLAKVHWRADTWELPGGQVEEGEALDQAVCREIKEET
CCCCCCHHEEEEEHHHCCCCCCEEEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHC
GLTVKPIGITGVYYNASMNILAVVFKVAYVSGEIKIQHEEIQEAKFVALNEENIDEYITR
CCEEEECEEEEEEECCCHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEECCCCHHHHHCC
PHMKSRTLDAMRSSHFIPYETWEVQPYNLIGRL
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MEHKTPKHIVAVAGYLTNEKDEVLLAKVHWRADTWELPGGQVEEGEALDQAVCREIKEET
CCCCCCHHEEEEEHHHCCCCCCEEEEEEEECCCCEECCCCCCCCCHHHHHHHHHHHHHHC
GLTVKPIGITGVYYNASMNILAVVFKVAYVSGEIKIQHEEIQEAKFVALNEENIDEYITR
CCEEEECEEEEEEECCCHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEECCCCHHHHHCC
PHMKSRTLDAMRSSHFIPYETWEVQPYNLIGRL
CCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA