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The map label for this gene is 227815437

Identifier: 227815437

GI number: 227815437

Start: 2606165

End: 2607424

Strand: Reverse

Name: 227815437

Synonym: BAMEG_2850

Alternate gene names: NA

Gene position: 2607424-2606165 (Counterclockwise)

Preceding gene: 227815438

Following gene: 227815436

Centisome position: 49.85

GC content: 35.56

Gene sequence:

>1260_bases
ATGAGGGTAGAAGTATGGGGAGGAGCGGGAGAATACGGTCGTTCCTGCTATTTCGTAAAAAATAAAGAGACAAAAATATT
ATTTGATTGTGGTATTAATCGATCATATGAGGATAGTTATCCAAAAATAGAGCGGGAAGTTGTACCGTTTTTAGATGCAG
TATTTTTATCACATATTCATGAAGATCATACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATCTGG
ACAACTCGTTATACGAAGGAGCAACTTCCCGCTTATTATGAAAAATGGAGAAACTACAATGTGACGCAAGGATGGAATGT
GCCATATAACGACCAAAATGTGAAAGATTTAAATTATATATATGTTGATGAGATTAGTAATCCGAATGAATGGATACAGA
TTACTCCAACATTGCGGTTTCAATGGGGGTATAGTGGGCACGTATTAGGATCGGTTTGGTTTTTAGTGGATATGAGTCAT
ACATATGTATTTTATTCTGGCGATTATTCAGCAGAGTCTAACATACTACGAGCGAATTTACCTGAGAAATTGCGCGGCGA
TATAAAAGTTGCAATTGTAGATGCCGCTTATCATACTGATGATGTTTCGCAACGTGAACGAGTAAACGAACTATGTACAG
AAATTGAACGAGCTGCGGGGAATAAAGGGATAGCATTACTACCATTGCCACCCCTTGGTAGGGCGCAAGATATCGTATTG
TATTTATATGAAAAATATAAAGAATTTCCCATTATAGTAGATCAGGAAATTTTAGATGGATTTGACGAGATGTTCTTATA
TAAAGATTGGATCAAAAATAATAAAGAACTTGAAGAGCTAATGGAGAGTTTAAAAAGAAACATAATAGTTATGGATGATG
ACGGCGGTACGCAACATAGTTATGGAATAGTTGTAATGAGTGATGCGAATATGCAAACGAAACGGGCTCAGTTATATTAT
GAACAAATTCGGCATGAAGAAAGAAATTCTATTATCTTTACTGGGCATGTTGCGAAAGGGAGTTTTGCAGAAAAAGTTTT
GAAAGAACGTATAGGTAAAGAATGTAGGGTGAAGCGAGTTCCATATAAAGTTCATCAAAGTATAAGAGATGTGAAAGAGA
TGTTAAATACATTATTACCGGAACATACGGTGTTAGTACACGCTTTAAAAGAGGATACAGATCGATTACAGAAAAAGCTT
AGCACGGCAGGGTATGAAAATGTATATTCACTTACTATGGAACGTATAGAAGTTATTTAA

Upstream 100 bases:

>100_bases
TATCTATTGGAATGGCGATGGCTGTCGTTTCAGTTGGACTTACAACGCTATGTTTATTACTTCTGCAGCATATGGAGCAA
AAACGAAAAGGGGTAGCATG

Downstream 100 bases:

>100_bases
CATGTAAAGGGGATAGGTATATGAAAAAAGTATTTGTATTCGTGAGTATTTTCTTTTGTTGTTTCCTTTATTCCGATAAG
GAAGGGTTTGCTGCTAGTCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKGIALLPLPPLGRAQDIVL
YLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Sequences:

>Translated_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKGIALLPLPPLGRAQDIVL
YLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI
>Mature_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKGIALLPLPPLGRAQDIVL
YLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSYGIVVMSDANMQTKRAQLYY
EQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=440, Percent_Identity=25, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=23.2346241457859, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566029, Length=434, Percent_Identity=22.8110599078341, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=433, Percent_Identity=22.1709006928406, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323307, Length=436, Percent_Identity=22.9357798165138, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24648013, Length=435, Percent_Identity=23.9080459770115, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21358523, Length=432, Percent_Identity=22.9166666666667, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 48992; Mature: 48992

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYI
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEEEEECCCCCCCCEEECCC
PEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKGIALLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
YLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHS
HHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCEE
YGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEECC
PYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYI
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEEEEECCCCCCCCEEECCC
PEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKGIALLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
YLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHS
HHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCEE
YGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEECC
PYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]