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The map label for this gene is mdmC [H]

Identifier: 227814734

GI number: 227814734

Start: 1952375

End: 1952959

Strand: Reverse

Name: mdmC [H]

Synonym: BAMEG_2144

Alternate gene names: 227814734

Gene position: 1952959-1952375 (Counterclockwise)

Preceding gene: 227814737

Following gene: 227814733

Centisome position: 37.34

GC content: 34.02

Gene sequence:

>585_bases
ATGGATACATTAAATTCATTATTATTTCAACTTGAACAATATGGAGAAGAGCATGATCGAAATAAAAAAACACGGGAAGA
AAAATTACGGAATATTTCTCGTGAGATGGGGCAATTTTTATCAATTTTAGTAAAAGGGTGTAGTGCAAAAAACATTTTAG
AAATTGGAACTTCTAATGGTTATTCTACATTGTGGTTAGCTGATGCGGTAGAAGAAACAAATGGAAATGTAACAACTGTA
GAGCTTTCCTCAGAACGAGTTGGAGAGGCACTTGCCAATTTTGAAAAGGCAAATCTTTTACAAAGGATTGATGTTCACAA
TCAAGAAGCAGGGGCATTTTTAGATTCACAACTAGATCATTCATTTGATTTTATTTTCCTAGATTCAGAGCGTACGCAAT
ACATGTGGTGGCTTGAGCATATAAAACGCGTTTTACAACCAAAAGGTCTTCTTGTTGTCGATAATGCTACTTCTCATGCG
AGTGAATTAGCTGAGTTTATAAAAATGATTGAAGAAGATAAAATGTTTGAAACAGTGTTATTGGCATTTCAAAATGGTGC
ATTTGTAGTGCGTAAGAAGCAATAG

Upstream 100 bases:

>100_bases
TGTCATATAACGAGAAAAAGGTTTTTGTTTCGCATATAATGAAAGTAGACGAGCAACAAGAGCTTTTTCATCATATTGCT
TTAGAAAGGCGATGAAAAAC

Downstream 100 bases:

>100_bases
GATTGAACGCAATATAATTATCACATTGAAAAAGGGTGTATGTCAAAAGATTGAGTACAGTAGGATGGGAAGGACGTAAT
TTATATATGTAACACACGAA

Product: O-methyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRVLQPKGLLVVDNATSHA
SELAEFIKMIEEDKMFETVLLAFQNGAFVVRKKQ

Sequences:

>Translated_194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRVLQPKGLLVVDNATSHA
SELAEFIKMIEEDKMFETVLLAFQNGAFVVRKKQ
>Mature_194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRVLQPKGLLVVDNATSHA
SELAEFIKMIEEDKMFETVLLAFQNGAFVVRKKQ

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 22245; Mature: 22245

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YSTLWLADAVEETNGNVTTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDH
CEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SFDFIFLDSERTQYMWWLEHIKRVLQPKGLLVVDNATSHASELAEFIKMIEEDKMFETVL
CEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LAFQNGAFVVRKKQ
HHHCCCEEEEEECC
>Mature Secondary Structure
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YSTLWLADAVEETNGNVTTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDH
CEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SFDFIFLDSERTQYMWWLEHIKRVLQPKGLLVVDNATSHASELAEFIKMIEEDKMFETVL
CEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LAFQNGAFVVRKKQ
HHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]