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The map label for this gene is coaBC [H]

Identifier: 227814267

GI number: 227814267

Start: 1538738

End: 1539427

Strand: Direct

Name: coaBC [H]

Synonym: BAMEG_1675

Alternate gene names: 227814267

Gene position: 1538738-1539427 (Clockwise)

Preceding gene: 227814266

Following gene: 227814268

Centisome position: 29.42

GC content: 36.09

Gene sequence:

>690_bases
ATGAAGGGGAAAAAGGTATTAATTACAAGCGGTGGTTGTTTAGAAAAGTGGGATCAAGTACGCGGACATACAAATATGGC
AAAAGGAACAATTGGAAGAATAATCGCCGAAGAGCTTATAAGTAAAGGGGCCCATGTTATATATTTACACGGTTATTTTG
CGGAGAAACCGAATGATATAAACAATCAATTAGAATTACACCCATTTGAAGGAATTATTGATTTACGAGATAAAATGAAA
AGTATCATTACGCATGAAAAAGTCGATGCGGTTATTATGGCAGCGGCTGGGTCTGATTGGGTTGTGGACAAAATTTGTGA
TCAAGAGGGCAATGTTCTTGATATGAATGGAAAAATCTCAAGTGATATAGCGCCAATTATACATTTTCAAAAGGCACCGA
AAGTATTAAAACAAATAAAACAGTGGGATTCAGAAACTGTACTCGTTGGCTTTAAACTTGAAAGTGATGTAAATGAAGAA
GAACTGTTTGAAAGAGCGAAAAATAGAATGGAAGAAGCGAAGGCAAGTGTAATGATTGCAAATTCACCACATTCTTTATA
TTCGCGCGGAGCAATGCACTACGTAATTGGACAAGACGGTAAAGGGCAGTTATGTAATGGAAAAGATGAAACAGCGAAAG
AAATTGTCAAAAGGTTAGAAGTACTATGTAATCACGTTACTGCTTTATAA

Upstream 100 bases:

>100_bases
GAAAATAGGAAACGCAAAGTGCCGTCTTATGAAACAACGTGATATAGTTGACTTTGGAACAGAATGGTTTCGTAAGAAAA
ATTAGTAAGGGATGGTTACG

Downstream 100 bases:

>100_bases
TTTCAAGTATTTGGATAAGAGTGAATCTGCATAGTATATATTGGTAAGCGAAACTTTTTGCTTTGATACAAACGTTAACC
ATTCAATATGGATACATAGA

Product: hypothetical protein

Products: NA

Alternate protein names: DNA/pantothenate metabolism flavoprotein; Phosphopantothenoylcysteine decarboxylase; PPCDC; CoaC; Phosphopantothenate--cysteine ligase; CoaB; PPC synthetase; PPCS; Phosphopantothenoylcysteine synthase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKGKKVLITSGGCLEKWDQVRGHTNMAKGTIGRIIAEELISKGAHVIYLHGYFAEKPNDINNQLELHPFEGIIDLRDKMK
SIITHEKVDAVIMAAAGSDWVVDKICDQEGNVLDMNGKISSDIAPIIHFQKAPKVLKQIKQWDSETVLVGFKLESDVNEE
ELFERAKNRMEEAKASVMIANSPHSLYSRGAMHYVIGQDGKGQLCNGKDETAKEIVKRLEVLCNHVTAL

Sequences:

>Translated_229_residues
MKGKKVLITSGGCLEKWDQVRGHTNMAKGTIGRIIAEELISKGAHVIYLHGYFAEKPNDINNQLELHPFEGIIDLRDKMK
SIITHEKVDAVIMAAAGSDWVVDKICDQEGNVLDMNGKISSDIAPIIHFQKAPKVLKQIKQWDSETVLVGFKLESDVNEE
ELFERAKNRMEEAKASVMIANSPHSLYSRGAMHYVIGQDGKGQLCNGKDETAKEIVKRLEVLCNHVTAL
>Mature_229_residues
MKGKKVLITSGGCLEKWDQVRGHTNMAKGTIGRIIAEELISKGAHVIYLHGYFAEKPNDINNQLELHPFEGIIDLRDKMK
SIITHEKVDAVIMAAAGSDWVVDKICDQEGNVLDMNGKISSDIAPIIHFQKAPKVLKQIKQWDSETVLVGFKLESDVNEE
ELFERAKNRMEEAKASVMIANSPHSLYSRGAMHYVIGQDGKGQLCNGKDETAKEIVKRLEVLCNHVTAL

Specific function: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine [H]

COG id: COG0452

COG function: function code H; Phosphopantothenoylcysteine synthetase/decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PPC synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005252
- InterPro:   IPR007085
- InterPro:   IPR003382 [H]

Pfam domain/function: PF04127 DFP; PF02441 Flavoprotein [H]

EC number: =4.1.1.36; =6.3.2.5 [H]

Molecular weight: Translated: 25507; Mature: 25507

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKKVLITSGGCLEKWDQVRGHTNMAKGTIGRIIAEELISKGAHVIYLHGYFAEKPNDI
CCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
NNQLELHPFEGIIDLRDKMKSIITHEKVDAVIMAAAGSDWVVDKICDQEGNVLDMNGKIS
CCCEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCEEEECCCCC
SDIAPIIHFQKAPKVLKQIKQWDSETVLVGFKLESDVNEEELFERAKNRMEEAKASVMIA
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEE
NSPHSLYSRGAMHYVIGQDGKGQLCNGKDETAKEIVKRLEVLCNHVTAL
CCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGKKVLITSGGCLEKWDQVRGHTNMAKGTIGRIIAEELISKGAHVIYLHGYFAEKPNDI
CCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
NNQLELHPFEGIIDLRDKMKSIITHEKVDAVIMAAAGSDWVVDKICDQEGNVLDMNGKIS
CCCEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCEEEECCCCC
SDIAPIIHFQKAPKVLKQIKQWDSETVLVGFKLESDVNEEELFERAKNRMEEAKASVMIA
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEE
NSPHSLYSRGAMHYVIGQDGKGQLCNGKDETAKEIVKRLEVLCNHVTAL
CCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]