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The map label for this gene is des [H]

Identifier: 227814197

GI number: 227814197

Start: 1469537

End: 1470292

Strand: Direct

Name: des [H]

Synonym: BAMEG_1605

Alternate gene names: 227814197

Gene position: 1469537-1470292 (Clockwise)

Preceding gene: 227814196

Following gene: 227814198

Centisome position: 28.1

GC content: 36.77

Gene sequence:

>756_bases
ATGGGTGTGTTAACGTTATTCCCATTTGATCAATGGGGGCATGATCATGCGATTCATCACGCTACAAGTGGTAATTTAGA
TAAGAGAGGTACAGGAGATATTTGGACGCTTACAGTGGATGAATATGTAGCTGCGCCACTTAGACTTCGTTTAGCATATC
GTTTATATCGCAATCCATTCGTTATGTTTGGGTTAGGTCCGATTTATGTATTCTTGCTTAAAAATAGATTTAACCGAAAA
GGTGCAAGACAGAAAGAACGTATGAATACGTATTTGACGAATATTATAATTGTTGCCGTAGTAGCTATACTTTGCTGGGC
AATAGGATGGCAATCGTTCCTATTAGTACATGGTACGATATTCTTAATTGCAGGTTCAGTAGGGATTTGGCTGTTTTACG
TACAGCACACATTCGAGGATTCTTATTTTGAAGAAGATAAAGATTGGGAATATGTGAAAGCGGCCGTAGAGGGAAGTTCA
TTTTATAAACTTCCAAAAATCTTGCAATTCCTAACTGGTAATATTGGATTCCATCATGTTCACCATTTAAGCCCAAGAGT
ACCAAACTATAAACTAGAAGAGGCACACAATAATACGCTTCCGTTAAAAAATGTACCAACGATTACACTTGCTACAAGCT
TGCGTTCACTTCGTTTCCGTCTTTGGGATGAGAAAAGTAACAATTTTGTTAGCTTTAAAGAAGTCAAAAATATAATTAAA
AATAATGTTTCTGTCCGGGTGAAATCGGAACTATAA

Upstream 100 bases:

>100_bases
AGCTGCTGGTTTTATGACACGAATTTTCATTATTTTTCATGATTGTACCCATTATTCATTCTTTAAAAGTCGACGTGCAA
ATAGAATAGTAGGGACATGT

Downstream 100 bases:

>100_bases
ATTCATCGGCTATAAAACTCCCCTTAATCATTATCGATGTAAGGGGAGTTTTTGTTATGTATAACTGATATCGGGGACGT
GGAAAAATACATGTGTAGAT

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGVLTLFPFDQWGHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRK
GARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSS
FYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIK
NNVSVRVKSEL

Sequences:

>Translated_251_residues
MGVLTLFPFDQWGHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRK
GARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSS
FYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIK
NNVSVRVKSEL
>Mature_250_residues
GVLTLFPFDQWGHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRKG
ARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSF
YKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIKN
NVSVRVKSEL

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 29068; Mature: 28937

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLTLFPFDQWGHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPF
CCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCE
VMFGLGPIYVFLLKNRFNRKGARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTI
EEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSFYKLPKILQFLTGNIGFHHV
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
HHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIK
HHCCCCCCCCCHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
NNVSVRVKSEL
CCCEEEEECCC
>Mature Secondary Structure 
GVLTLFPFDQWGHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPF
CEEEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCE
VMFGLGPIYVFLLKNRFNRKGARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTI
EEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSFYKLPKILQFLTGNIGFHHV
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
HHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIK
HHCCCCCCCCCHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
NNVSVRVKSEL
CCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]