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The map label for this gene is msmR [H]

Identifier: 227813891

GI number: 227813891

Start: 1173032

End: 1173859

Strand: Direct

Name: msmR [H]

Synonym: BAMEG_1297

Alternate gene names: 227813891

Gene position: 1173032-1173859 (Clockwise)

Preceding gene: 227813889

Following gene: 227813892

Centisome position: 22.43

GC content: 37.44

Gene sequence:

>828_bases
GTGAAGTTGGACGTGAATGAGTTAGCAGAGTATCTTGCCAATACTCCTTTCCGAGTAGAAGGAGTATATCGTTATGCTAA
AAATCCAGGTGTGCCTTGTGCTGAGTCCACAGATTCTTTCCCAGGATTTGTATTTCCACTTACAGGGAAGACGGAATTTC
AATTTAATGGTACGCCGTATACCCTTTCCCCAGGAAAAGTTATACATGGGGGTGCAAAAATGACATTAGCCCATAAAATG
CTTGGTGAAATAAACTGGGAATATATTCTTGTTTTATATCGGATAAGCAATTCAGAACGAGAAGACTCTGGCTTTACTCA
TCAGCATTTTGAATTATTAACAGGACAATCTCCTCGTCTTGTCGAATTACTTATGCGTCTTTGGGATGTGTATAATCAGC
GAGGAGGCATTTCGATGTTTCAGACTGAAATGCTATTTCGCGAAGCGTTGAATGAAGCTTTATTAAGTGTTGTCAATAGA
GAAAACAACTATGAATCGCATACTTTATTCGAACGAATATCTAGTTACGTTCATAAATACTATTATAAAGATATTACAAT
ACATACACTTACAGAACAAAATAATGTTAATCGAAATCGTCTTTCTTACGTGTTTAGAAAGCATGCAGGTATGGGGCCAG
CAGAATATTTATTGAACTATCGTATAAAGATGGCTCAAAAAATGTTATGTACAAGTGGTGTGCCTGTACAACAAATTGCG
CAGGCTGTTGGAATCGCAGACCCTTTTTATTTTAGTAGGGTTTTCAAGAAGCGAGTTGGCATTTCGCCTACTAAATATCG
CGAGAAGTTCATCAATAATCCATACTAA

Upstream 100 bases:

>100_bases
TTAAGTCGTATGTACTATTTTTAGTTTAGCGTTGCCCAGAATGTACACCAATTAATCTCGTGAATTACAAGAAAACTATT
ATTGAAATGAGGCTTGCATT

Downstream 100 bases:

>100_bases
TGTCAACAGGGGTCCATTCTTATTTGAAAATCACTGTTCTATACTTATGGAGAGTTAAAGGAAACATTGGATTGAAAGTA
CTTTCATTGAAATCACTCCT

Product: transcriptional regulator, AraC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKLDVNELAEYLANTPFRVEGVYRYAKNPGVPCAESTDSFPGFVFPLTGKTEFQFNGTPYTLSPGKVIHGGAKMTLAHKM
LGEINWEYILVLYRISNSEREDSGFTHQHFELLTGQSPRLVELLMRLWDVYNQRGGISMFQTEMLFREALNEALLSVVNR
ENNYESHTLFERISSYVHKYYYKDITIHTLTEQNNVNRNRLSYVFRKHAGMGPAEYLLNYRIKMAQKMLCTSGVPVQQIA
QAVGIADPFYFSRVFKKRVGISPTKYREKFINNPY

Sequences:

>Translated_275_residues
MKLDVNELAEYLANTPFRVEGVYRYAKNPGVPCAESTDSFPGFVFPLTGKTEFQFNGTPYTLSPGKVIHGGAKMTLAHKM
LGEINWEYILVLYRISNSEREDSGFTHQHFELLTGQSPRLVELLMRLWDVYNQRGGISMFQTEMLFREALNEALLSVVNR
ENNYESHTLFERISSYVHKYYYKDITIHTLTEQNNVNRNRLSYVFRKHAGMGPAEYLLNYRIKMAQKMLCTSGVPVQQIA
QAVGIADPFYFSRVFKKRVGISPTKYREKFINNPY
>Mature_275_residues
MKLDVNELAEYLANTPFRVEGVYRYAKNPGVPCAESTDSFPGFVFPLTGKTEFQFNGTPYTLSPGKVIHGGAKMTLAHKM
LGEINWEYILVLYRISNSEREDSGFTHQHFELLTGQSPRLVELLMRLWDVYNQRGGISMFQTEMLFREALNEALLSVVNR
ENNYESHTLFERISSYVHKYYYKDITIHTLTEQNNVNRNRLSYVFRKHAGMGPAEYLLNYRIKMAQKMLCTSGVPVQQIA
QAVGIADPFYFSRVFKKRVGISPTKYREKFINNPY

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=282, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31832; Mature: 31832

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDVNELAEYLANTPFRVEGVYRYAKNPGVPCAESTDSFPGFVFPLTGKTEFQFNGTPY
CCCCHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCE
TLSPGKVIHGGAKMTLAHKMLGEINWEYILVLYRISNSEREDSGFTHQHFELLTGQSPRL
EECCCCEEECCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCHH
VELLMRLWDVYNQRGGISMFQTEMLFREALNEALLSVVNRENNYESHTLFERISSYVHKY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YYKDITIHTLTEQNNVNRNRLSYVFRKHAGMGPAEYLLNYRIKMAQKMLCTSGVPVQQIA
HHHCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QAVGIADPFYFSRVFKKRVGISPTKYREKFINNPY
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKLDVNELAEYLANTPFRVEGVYRYAKNPGVPCAESTDSFPGFVFPLTGKTEFQFNGTPY
CCCCHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCE
TLSPGKVIHGGAKMTLAHKMLGEINWEYILVLYRISNSEREDSGFTHQHFELLTGQSPRL
EECCCCEEECCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCHH
VELLMRLWDVYNQRGGISMFQTEMLFREALNEALLSVVNRENNYESHTLFERISSYVHKY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YYKDITIHTLTEQNNVNRNRLSYVFRKHAGMGPAEYLLNYRIKMAQKMLCTSGVPVQQIA
HHHCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QAVGIADPFYFSRVFKKRVGISPTKYREKFINNPY
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]