BacMap

Definition	Bacillus anthracis str. CDC 684, complete genome.
Accession	NC_012581
Length	5,230,115

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The map label for this gene is yvaG [H]

Identifier: 227813784

GI number: 227813784

Start: 1075663

End: 1076457

Strand: Direct

Name: yvaG [H]

Synonym: BAMEG_1188

Alternate gene names: 227813784

Gene position: 1075663-1076457 (Clockwise)

Preceding gene: 227813783

Following gene: 227813786

Centisome position: 20.57

GC content: 37.99

Gene sequence:

>795_bases
ATGCATATGCAATTAAAAGGAAAAACAGCACTGGTTACCGGATCTACGGCAGGGATTGGAAAAGCAATTGCCACTTCATT
AGTAGCAGAAGGAGCTAATGTACTTATTAATGGACGCCGTGAAGAAAATGTTAATGAAACGATAAAAGAAATTCGAGCGC
AGTATCCTGATGCTATCCTTCAACCCGTAGTAGCTGATTTAGGAACAGAACAAGGGTGCCAAAATGTGATTGAAAAGTAC
CCTAAAGTAGACATTCTTATTAACAACTTAGGAATTTTTGAACCTGTAGAATATTTTGATATCCCTGATGAAGATTGGTT
TAAATTGTTTGAAGTCAATATTATGAGTGGTGTTCGACTTACTCGTTCGTACTTGAAAAAAATGATTGAAAGAAAAGAAG
GAAGAGTCATCTTTATTGCTAGCGAAGCAGCTATTATGCCCTCTCAAGAAATGGCTCATTATAGTGCGACTAAAACGATG
CAACTCTCACTTTCTCGCAGTTTAGCTGAGCTGACGACAGGAACGAATGTAACTGTTAATACTATAATGCCTGGTTCGAC
TTTAACGGAAGGAGTGGAGACTATGTTAAATAGTCTGTATCCTAATGAGCAATTGACAATAGAAGAAGCTGAGAAGCGAT
TTATGAAAGAGAATCGACCAACCTCTATCATTCAAAGACTTATTCGACCAGAAGAAATTGCTCATCTTGTCACTTTCTTA
AGTAGCCCACTTTCTTCAGCAATTAATGGTTCCGCGTTGCGAATAGACGGGGGATTAGTACGTAGTGTATTTTAA

Upstream 100 bases:

>100_bases
TATTTTCTGTTAAAGATATGAGAAGTGAACCACAATATAAACGTAATTATTTATTCCAACGTAAGTCAATCATTTAGCAC
ATGAATTTGGAGGGATCTAT

Downstream 100 bases:

>100_bases
AAAATTAAAAACAACATTATATTCTGTTGAAGATAAAGTAAATGAGTTGTATTTTATCTATTAACGGAAATATAGAAAAA
GCAAATTGCAACATGCAAAC

Product: oxidoreductase, short chain dehydrogenase/reductase family

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MHMQLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAILQPVVADLGTEQGCQNVIEKY
PKVDILINNLGIFEPVEYFDIPDEDWFKLFEVNIMSGVRLTRSYLKKMIERKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSLSRSLAELTTGTNVTVNTIMPGSTLTEGVETMLNSLYPNEQLTIEEAEKRFMKENRPTSIIQRLIRPEEIAHLVTFL
SSPLSSAINGSALRIDGGLVRSVF

Sequences:

>Translated_264_residues
MHMQLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAILQPVVADLGTEQGCQNVIEKY
PKVDILINNLGIFEPVEYFDIPDEDWFKLFEVNIMSGVRLTRSYLKKMIERKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSLSRSLAELTTGTNVTVNTIMPGSTLTEGVETMLNSLYPNEQLTIEEAEKRFMKENRPTSIIQRLIRPEEIAHLVTFL
SSPLSSAINGSALRIDGGLVRSVF
>Mature_264_residues
MHMQLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAILQPVVADLGTEQGCQNVIEKY
PKVDILINNLGIFEPVEYFDIPDEDWFKLFEVNIMSGVRLTRSYLKKMIERKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSLSRSLAELTTGTNVTVNTIMPGSTLTEGVETMLNSLYPNEQLTIEEAEKRFMKENRPTSIIQRLIRPEEIAHLVTFL
SSPLSSAINGSALRIDGGLVRSVF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=29.2307692307692, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=30.2325581395349, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4504505, Length=212, Percent_Identity=29.7169811320755, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=26.7148014440433, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226371731, Length=185, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=31.5217391304348, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=31.7204301075269, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=29.045643153527, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4557649, Length=217, Percent_Identity=28.110599078341, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4503817, Length=278, Percent_Identity=25.5395683453237, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=27.8606965174129, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI10190746, Length=212, Percent_Identity=29.2452830188679, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=23.7354085603113, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40807363, Length=205, Percent_Identity=26.3414634146341, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=30.7392996108949, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=31.3953488372093, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787905, Length=264, Percent_Identity=31.0606060606061, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=30.0751879699248, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=30.3846153846154, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=27.9693486590038, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=28.0769230769231, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=25.0950570342205, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=24.7104247104247, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=29.2181069958848, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=24.8091603053435, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=27.6515151515151, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=218, Percent_Identity=27.0642201834862, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=32.0610687022901, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=31.2727272727273, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17568967, Length=215, Percent_Identity=28.8372093023256, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=31.203007518797, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=30.4832713754647, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=28.8888888888889, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.5589353612167, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=28.740157480315, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=29.2592592592593, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=29.8181818181818, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=27.4074074074074, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=275, Percent_Identity=28.3636363636364, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=28.1021897810219, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.1970802919708, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=29.1044776119403, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=29.6703296703297, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=26.0700389105058, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=27.2030651340996, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=28.7272727272727, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=29.8850574712644, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=27.4074074074074, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=163, Percent_Identity=32.5153374233129, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=29.3269230769231, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.4615384615385, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=208, Percent_Identity=27.4038461538462, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=25.7352941176471, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=273, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=268, Percent_Identity=30.2238805970149, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=185, Percent_Identity=30.8108108108108, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559552, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=27.2277227722772, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=22.9007633587786, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=169, Percent_Identity=28.9940828402367, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=28.0612244897959, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=29.4573643410853, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=28.957528957529, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=27.1317829457364, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=32.620320855615, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=32.620320855615, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=27.0992366412214, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28574402, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.5336787564767, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=27.3148148148148, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=25.968992248062, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17737361, Length=272, Percent_Identity=26.8382352941176, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24647946, Length=199, Percent_Identity=26.6331658291457, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553409, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647948, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356301, Length=238, Percent_Identity=27.3109243697479, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584752, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331216, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24649181, Length=223, Percent_Identity=26.0089686098655, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355631, Length=159, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 29219; Mature: 29219

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMQLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAIL
CCEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHH
QPVVADLGTEQGCQNVIEKYPKVDILINNLGIFEPVEYFDIPDEDWFKLFEVNIMSGVRL
HHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
TRSYLKKMIERKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSLSRSLAELTTGTNVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIMPGSTLTEGVETMLNSLYPNEQLTIEEAEKRFMKENRPTSIIQRLIRPEEIAHLVTFL
EECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHH
SSPLSSAINGSALRIDGGLVRSVF
HHHHHHHCCCCEEEECCCHHHHCC
>Mature Secondary Structure
MHMQLKGKTALVTGSTAGIGKAIATSLVAEGANVLINGRREENVNETIKEIRAQYPDAIL
CCEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHH
QPVVADLGTEQGCQNVIEKYPKVDILINNLGIFEPVEYFDIPDEDWFKLFEVNIMSGVRL
HHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
TRSYLKKMIERKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSLSRSLAELTTGTNVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIMPGSTLTEGVETMLNSLYPNEQLTIEEAEKRFMKENRPTSIIQRLIRPEEIAHLVTFL
EECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHH
SSPLSSAINGSALRIDGGLVRSVF
HHHHHHHCCCCEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]