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The map label for this gene is pbp [H]

Identifier: 227813718

GI number: 227813718

Start: 1017641

End: 1018678

Strand: Reverse

Name: pbp [H]

Synonym: BAMEG_1122

Alternate gene names: 227813718

Gene position: 1018678-1017641 (Counterclockwise)

Preceding gene: 227813719

Following gene: 227813713

Centisome position: 19.48

GC content: 35.26

Gene sequence:

>1038_bases
ATGAAATTAAAAAGTAACAATATATACGAAAAAATGAACCAATATTCTGTTGTAGGTTTAAGTCTTGCTGTTATACGCGA
CGGCAAACTAGATGAAACAGCTGCTTTCGGAACGCTTGAATCCGGAACTAATAGAACTGTCACTATAGATTCCATATTCA
ATTCTTGTTCTATTAGTAAATTTATCACCACAATTCTCATACTAACATTATCCGATCTCAAAATCGTACATTTAGACGAA
GACGTTAATGATAGACTCACATCTTGGAACATCCCTACTAATCTATTTACTTCACAGAAAAAAGTCACATTGCGAAACTT
GTTAAGTCACCAATCTGGAATCATTGATCCTCCTAATAGCTTTGAACATTATCTACTTGCACAAGGGCAACCAAACATGT
CTGAACTCCTTGCCGGTAAAACATTATATTGCTCCGTACCTATTGAAGTAACTTATAAACCAGAAAGCGAATTTCACTAC
TCGGATGCAAACTTTTGTATAATCGAAATACTACTTGAAGATATAACTGGAAAGCCATTCAACCTTTTACTAGAAGAATC
TATATTTCAACCACTGCAAATGAAGAATAGTACAATCTTCTCTCCTGAAGACATAGATAAAACCGATGCTTTTGCTTGCG
GACATAATAAAGATGGCACCGTTACAAATGAGAAGTATCCATTTTATCCATTCGCAGCTGCTTCAGGTATTTGGACAACA
CCAACTGACTTATCAGCTTTAGTTATTGAAATCATTCATTCCTTACAAGGAAAAGGCAAACTAAAACTTTCTCAAAAAAC
AGTACAAGATATGATTTCTCCTCAAGGTTGCTCAAAATGGACTGGCTTAGGTGTTTTTCTAGATGATTTGAATGAAGACT
TACAAATTTATTCACTCGGATGGGGCGTTGGATTTCAATGTATGATGATATGCTATCCATACCGAGGTAATGGCGCTATT
ATAATGACGAACGCTGACTTAGGTGTTCATCAAATGGAAGGGATTATTGGTGACGTTTTAAAAACGTTATCGTTATAA

Upstream 100 bases:

>100_bases
TCATCTTTAATCGATGAAGTTTTTCTTTTTCTCTCATTCTCTCTATTTACTACTGTATAATAGAACTAACATTCTGTCTT
TTTTGAAGAAAGGAGTCACT

Downstream 100 bases:

>100_bases
TGAAAAAGAAAGAAGCTGTTCCTTTCAGCTTCTTTCTTATATAACATTTTTCGCAACAATTTTTATATGTTCTGGTGCGA
TAATCTCCGTTATACTTTCT

Product: putative penicillin-binding protein

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKLKSNNIYEKMNQYSVVGLSLAVIRDGKLDETAAFGTLESGTNRTVTIDSIFNSCSISKFITTILILTLSDLKIVHLDE
DVNDRLTSWNIPTNLFTSQKKVTLRNLLSHQSGIIDPPNSFEHYLLAQGQPNMSELLAGKTLYCSVPIEVTYKPESEFHY
SDANFCIIEILLEDITGKPFNLLLEESIFQPLQMKNSTIFSPEDIDKTDAFACGHNKDGTVTNEKYPFYPFAAASGIWTT
PTDLSALVIEIIHSLQGKGKLKLSQKTVQDMISPQGCSKWTGLGVFLDDLNEDLQIYSLGWGVGFQCMMICYPYRGNGAI
IMTNADLGVHQMEGIIGDVLKTLSL

Sequences:

>Translated_345_residues
MKLKSNNIYEKMNQYSVVGLSLAVIRDGKLDETAAFGTLESGTNRTVTIDSIFNSCSISKFITTILILTLSDLKIVHLDE
DVNDRLTSWNIPTNLFTSQKKVTLRNLLSHQSGIIDPPNSFEHYLLAQGQPNMSELLAGKTLYCSVPIEVTYKPESEFHY
SDANFCIIEILLEDITGKPFNLLLEESIFQPLQMKNSTIFSPEDIDKTDAFACGHNKDGTVTNEKYPFYPFAAASGIWTT
PTDLSALVIEIIHSLQGKGKLKLSQKTVQDMISPQGCSKWTGLGVFLDDLNEDLQIYSLGWGVGFQCMMICYPYRGNGAI
IMTNADLGVHQMEGIIGDVLKTLSL
>Mature_345_residues
MKLKSNNIYEKMNQYSVVGLSLAVIRDGKLDETAAFGTLESGTNRTVTIDSIFNSCSISKFITTILILTLSDLKIVHLDE
DVNDRLTSWNIPTNLFTSQKKVTLRNLLSHQSGIIDPPNSFEHYLLAQGQPNMSELLAGKTLYCSVPIEVTYKPESEFHY
SDANFCIIEILLEDITGKPFNLLLEESIFQPLQMKNSTIFSPEDIDKTDAFACGHNKDGTVTNEKYPFYPFAAASGIWTT
PTDLSALVIEIIHSLQGKGKLKLSQKTVQDMISPQGCSKWTGLGVFLDDLNEDLQIYSLGWGVGFQCMMICYPYRGNGAI
IMTNADLGVHQMEGIIGDVLKTLSL

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=354, Percent_Identity=27.4011299435028, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 38302; Mature: 38302

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKSNNIYEKMNQYSVVGLSLAVIRDGKLDETAAFGTLESGTNRTVTIDSIFNSCSISK
CCCCCCCHHHHHCCEEEEEEEEEEEECCCCCCHHHCCCCCCCCCCEEEHHHHHCCCCHHH
FITTILILTLSDLKIVHLDEDVNDRLTSWNIPTNLFTSQKKVTLRNLLSHQSGIIDPPNS
HHHHHHHHHHCCEEEEEECCCCCCCCEECCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCC
FEHYLLAQGQPNMSELLAGKTLYCSVPIEVTYKPESEFHYSDANFCIIEILLEDITGKPF
CCCEEEECCCCCHHHHHCCCEEEEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCCH
NLLLEESIFQPLQMKNSTIFSPEDIDKTDAFACGHNKDGTVTNEKYPFYPFAAASGIWTT
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCC
PTDLSALVIEIIHSLQGKGKLKLSQKTVQDMISPQGCSKWTGLGVFLDDLNEDLQIYSLG
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEE
WGVGFQCMMICYPYRGNGAIIMTNADLGVHQMEGIIGDVLKTLSL
CCCCEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKSNNIYEKMNQYSVVGLSLAVIRDGKLDETAAFGTLESGTNRTVTIDSIFNSCSISK
CCCCCCCHHHHHCCEEEEEEEEEEEECCCCCCHHHCCCCCCCCCCEEEHHHHHCCCCHHH
FITTILILTLSDLKIVHLDEDVNDRLTSWNIPTNLFTSQKKVTLRNLLSHQSGIIDPPNS
HHHHHHHHHHCCEEEEEECCCCCCCCEECCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCC
FEHYLLAQGQPNMSELLAGKTLYCSVPIEVTYKPESEFHYSDANFCIIEILLEDITGKPF
CCCEEEECCCCCHHHHHCCCEEEEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCCH
NLLLEESIFQPLQMKNSTIFSPEDIDKTDAFACGHNKDGTVTNEKYPFYPFAAASGIWTT
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCC
PTDLSALVIEIIHSLQGKGKLKLSQKTVQDMISPQGCSKWTGLGVFLDDLNEDLQIYSLG
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEE
WGVGFQCMMICYPYRGNGAIIMTNADLGVHQMEGIIGDVLKTLSL
CCCCEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]