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The map label for this gene is pyrR

Identifier: 227813200

GI number: 227813200

Start: 527459

End: 528001

Strand: Direct

Name: pyrR

Synonym: BAMEG_0599

Alternate gene names: 227813200

Gene position: 527459-528001 (Clockwise)

Preceding gene: 227813199

Following gene: 227813201

Centisome position: 10.09

GC content: 37.57

Gene sequence:

>543_bases
ATGCAAGAGAAAGCTGTCGTTTTAGATGACCAAATGATTCGCCGCGCTTTAACACGAATTAGTCATGAAATCGTGGAACG
AAATAAAGGTGTCGATAATTGTGTTCTTGTCGGAATTAAAACTCGTGGAATTTTTATTGCACAACGTTTGGCAGAACGAA
TTGGTCAAATTGAAGGAAAAGAAATGGAAGTTGGAGAGTTAGACATTACGTTATATCGAGATGATTTAACACTACAATCG
AAAAATAAAGAACCACTTGTAAAAGGTTCTGATATCCCTGTAGATATTACGAAGAAAAAAGTTATCCTTGTGGATGATGT
ATTATATACAGGCAGAACTGTTCGAGCAGCAATGGATGCTCTTATGGATTTAGGGAGACCATCACAAATCCAACTAGCGG
TTCTTGTTGATAGAGGTCATCGTGAACTACCAATTCGCGCTGATTATGTAGGAAAGAACATTCCAACATCAAGTGAAGAG
CGTATCGAAGTTGATTTGCAAGAGACAGATCAACAAGATCGAGTAAGCATATACGATAAGTAA

Upstream 100 bases:

>100_bases
GGTATGCTGTACCCTTTTTCAAAAGTCCTCTCGCACACGCTGAGAGGACTTTTTTTATACCATTACTCTCACGCAAGAAA
AAAGCTTGGAGGTGTAGAGC

Downstream 100 bases:

>100_bases
AGCCCTTTTAAATGTAGTCCTGTGAGGCTGCCAAAGGGTCTTGGCTTTCATATGTCAAATTTGGCATACGAAAGTGTAGG
ACTCTTTGTGCACAGGCACA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQS
KNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEE
RIEVDLQETDQQDRVSIYDK

Sequences:

>Translated_180_residues
MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQS
KNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEE
RIEVDLQETDQQDRVSIYDK
>Mature_180_residues
MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQS
KNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEE
RIEVDLQETDQQDRVSIYDK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_BACAA (C3P661)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868127.1
- ProteinModelPortal:   C3P661
- SMR:   C3P661
- EnsemblBacteria:   EBBACT00000126037
- GeneID:   7848464
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4055
- GeneTree:   EBGT00050000000816
- ProtClustDB:   PRK05205
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20410; Mature: 20410

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGK
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCC
EMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDA
EEEECEEEEEEEECCEEEECCCCCCCCCCCCCCEEECCCEEEEEECHHHCCCHHHHHHHH
LMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
HHHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEHHHCCCCCCEEECCC
>Mature Secondary Structure
MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGK
CCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCC
EMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDA
EEEECEEEEEEEECCEEEECCCCCCCCCCCCCCEEECCCEEEEEECHHHCCCHHHHHHHH
LMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
HHHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA