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The map label for this gene is murG [H]

Identifier: 227813180

GI number: 227813180

Start: 509097

End: 510248

Strand: Direct

Name: murG [H]

Synonym: BAMEG_0578

Alternate gene names: 227813180

Gene position: 509097-510248 (Clockwise)

Preceding gene: 227813179

Following gene: 227813181

Centisome position: 9.73

GC content: 36.63

Gene sequence:

>1152_bases
ATGTATATAGAAATAAATACGACTGAAATAAGAAAAAGAGAAGCGGAGGAGTTAGTAGTGCGTGTATTAGTAAGTGGTGG
GGGCACTGGAGGTCATATTTATCCGGCTCTTGCTTTAATAAGAGAAATAAAAAAATTAAATCCGGAAGCAAGGTTTTTAT
ATATTGGTACGGAAAATGGATTAGAGAGTACAATCGTTCCAAAAGCAGGTATACCGTTTCAATCTATTGTTATAAGTGGA
TTTAAGCGTAAAATATCGTTAGATAACGTGAAAACGGTGATGCGTTTCCTAAAAGGTGTACAAGACAGTAAGCGATATAT
TCGTCGTTTCAATCCAGATATTGTAATTGGAACGGGTGGATATGTATGTGGACCTGTTGTATATGCTGCGGCAAAATTAG
GTATTCCAACGATTGTACATGAACAAAATAGTGTACCTGGTGTAACGAATAAATTTTTAAGCCGCTATGTTGATAAAGTT
GCAGTTTGTTTTGAAGCGGCTGCAGAACATTTTCCACAGTCAAAAGTGGTCATGACAGGAAATCCACGAGCGTCAGAAGT
AATGGATCAAAATGGAATGAAAGGAAAACGTTCAGTAGGTTTATCCCTTCCTAAAAAATCCGTGCTTATTTTTGGTGGAA
GCCGTGGGGCTAGACCAATTAACGATGCTTTCGTAGAGGCGATTGAACAGTTTGGAAATAAAAGTTACGAAATATTGTAT
GTAACAGGTGAAGTTCATTATGACAAAGTGATGGAAGCAGTGAAGCAAAAAGGGAATCCGAATAATGTTATTATTAAACC
TTTCATTCATAATATGCCAGAAGTACTTACAGGTGTAGATCTTGTTGTTTCAAGAGCTGGGGCAACAACACTTGCAGAAT
TAACAGCGTTAGGTAAGCCGAGTGTGTTAATTCCGAGTCCGTATGTAACAAATAACCATCAGGAAAAAAATGCACGTTCT
GTTGTCGATAAAGGAGCAGCAAAAATGTTGCTTGAAAAAGATTTAACAGCTGAAACACTTATTCGTGATATTGATGAGAT
TTTATTAGATGCACAAACATTACAAAATATGAAGCTTGCTGCTGGGCAATTAGGTATTCCAGATGCAGCAAATAAGCTGT
ATGAAGTCATGAATAAGCTTGTAAAAAAATAA

Upstream 100 bases:

>100_bases
GTTAATGGCAGTAGGTGTATTATTAAATATAAGTCGCCATTCTCGCTACTAAACCCTGTTTTATAAGACAGGGTTTTTCG
TATGTGCGTGAAGAAACAAT

Downstream 100 bases:

>100_bases
CGTTAGGTGAACGCCCTGCATACTACTGTAATAAGGATGCTGAGTATGGGGGAGATTGTTTATGGAGCAATTAGTAAATG
AGCTTATACAAGCAAATGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 1 [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MYIEINTTEIRKREAEELVVRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISG
FKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKV
AVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILY
VTGEVHYDKVMEAVKQKGNPNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARS
VVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Sequences:

>Translated_383_residues
MYIEINTTEIRKREAEELVVRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISG
FKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKV
AVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILY
VTGEVHYDKVMEAVKQKGNPNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARS
VVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK
>Mature_383_residues
MYIEINTTEIRKREAEELVVRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISG
FKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKV
AVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILY
VTGEVHYDKVMEAVKQKGNPNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARS
VVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=31.767955801105, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 41888; Mature: 41888

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIEINTTEIRKREAEELVVRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENG
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
LESTIVPKAGIPFQSIVISGFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGG
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCC
YVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTG
HHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
NPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILY
CCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
VTGEVHYDKVMEAVKQKGNPNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKP
EECCCCHHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCC
SVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLA
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLGIPDAANKLYEVMNKLVKK
CCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYIEINTTEIRKREAEELVVRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENG
CEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
LESTIVPKAGIPFQSIVISGFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGG
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCC
YVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTG
HHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
NPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILY
CCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
VTGEVHYDKVMEAVKQKGNPNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKP
EECCCCHHHHHHHHHHCCCCCCEEEEHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCC
SVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLA
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLGIPDAANKLYEVMNKLVKK
CCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]