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The map label for this gene is nrdR [H]

Identifier: 227082396

GI number: 227082396

Start: 2363463

End: 2363933

Strand: Reverse

Name: nrdR [H]

Synonym: VCM66_2195

Alternate gene names: 227082396

Gene position: 2363933-2363463 (Counterclockwise)

Preceding gene: 227082397

Following gene: 227082395

Centisome position: 81.73

GC content: 47.56

Gene sequence:

>471_bases
TTGCCTTGTTATGGAGGTAATATGCATTGTCCTTTCTGTTCTGAAAACGATACCAAAGTGATCGATTCACGTCTGGTGGC
TGACGGACATCAAGTGCGCCGTCGTCGTCAGTGTCTGGCTTGTAATGAGCGCTTTACCACCTTTGAAACCGCGGAGTTAG
TGATGCCGCGCGTGATCAAATCGAATGGTAATCGTGAGCCTTTTGATGAAGAGAAAATGATTGGTGGCTTGCAGCGCGCA
TTGGAAAAGCGCCCAGTGAGTGCAGATGCGATTGAACTGGCGATCAGCACCATAAAATCTAAGCTACGTGCCACTGGCGA
GCGTGAAGTTCCGAGTAAACTGATTGGTAACTTGGTGATGGAACAGCTGAAAGTGCTAGATAAAGTGGCCTATATTCGCT
TTGCATCCGTATATCGTAGTTTTGAAGATGTCCGTGAATTTGGCGAGGAGATCGCCAAACTGCAGGACTAA

Upstream 100 bases:

>100_bases
CAATTACCTGTCACGCAGCTAAAATTCAAGCAAAGATGTGATGTAAAGGGGCTTCGCGCCCCTTTTTCTTTGGCTCTCAA
CAGCACATCGGCTACACTGG

Downstream 100 bases:

>100_bases
CCGATAGGATTAACTGAAAGCGATTATGCCTATGTTTACCTCTTTTGATCATCAAATGATGTCTCGCGCGATTGAACTTG
CGTGGCGCGGGCGTTTTACC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MPCYGGNMHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRA
LEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD

Sequences:

>Translated_156_residues
MPCYGGNMHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRA
LEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
>Mature_155_residues
PCYGGNMHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRAL
EKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=79.1946308724832, Blast_Score=246, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17755; Mature: 17623

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCYGGNMHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIK
CCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SNGNREPFDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVM
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PCYGGNMHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIK
CCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SNGNREPFDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVM
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA