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The map label for this gene is ribD [H]

Identifier: 227082395

GI number: 227082395

Start: 2362334

End: 2363437

Strand: Reverse

Name: ribD [H]

Synonym: VCM66_2194

Alternate gene names: 227082395

Gene position: 2363437-2362334 (Counterclockwise)

Preceding gene: 227082396

Following gene: 227082394

Centisome position: 81.71

GC content: 51.9

Gene sequence:

>1104_bases
ATGCCTATGTTTACCTCTTTTGATCATCAAATGATGTCTCGCGCGATTGAACTTGCGTGGCGCGGGCGTTTTACCACTTC
TCCTAATCCTAATGTCGGCTGCGTGATCACTCGCGGTGAGCAGATTGTAGGGGAAGGTTTCCATTTTCGCGCGGGCGAAC
CCCATGCTGAAGTGCATGCTATGCGCCAAGCCGGTGAGCTTACTCGCGGTGCGACCGCTTATGTCACTTTAGAGCCTTGC
TCTCATTATGGTCGCACACCGCCTTGTGCTGAAGGGCTTATTAAAGCCGGGGTTGCGAAAGTGATTTGCGCAATGCAAGA
CCCTAACCCACAAGTGGCGGGGAAGGGCGTACAAATGCTGCGTGATGCCGGGATTGAGGTTGAAGTGGGGTTGCTGGAAG
CGGATGCTCGAGTACTCAACCGCGGTTTTCTAAAACGTATGGAAACCGGCATGCCTTTTGTGCAGCTTAAAATGGCGGCG
AGTCTCGATGGACAAACCGCGCTCGCTAACGGTAAAAGCCAGTGGATTACCTCTCCTGCAGCACGTAAAGATGTTCAGCG
GTTTCGCGCGCAAGCCAGTGCGATTCTCTCCACCAGTCAAACGGTGCTGGCGGATAATGCTTCTCTGGCGGTGCGTTGGT
ACGATTTACCGTCATCGGTACAGGCGCAATACGCAGAAGCGGATTTGCGTCAGCCACTGCGGGTGATTTTGGATCGTCAA
CATCAATTGCATCCAGAGTTAGCGTTATACCAAACACCTTCACCCGTGCTGCGAGTTGCCAGCGAGAATGCCGAACTCTG
TATCTCTGCTGAGAACGGAAAGCTTGATTTGCGTGAGCTTTTGGCACTACTCGCTCAGCAACACAATGTGAATCAACTCT
GGGTAGAGGCGGGGAGCCAACTGGCTCAATCTTTGATTGAGCAAAAGTTGGTGGATGAAATCATTCTCTATTTAGCGCCG
AAACTGATGGGCAGTGATGGCCGTGGTTTATTTGGCGCGCTCGGTTTGACGGAAATGGCTGAGGCCATTGAACTCAAAAT
AGAAGATTGTCGAATGGTGGGGGCAGATTTGCGGATCATCGCCACCCCAAAAACAAAAGATTAG

Upstream 100 bases:

>100_bases
CGCTTTGCATCCGTATATCGTAGTTTTGAAGATGTCCGTGAATTTGGCGAGGAGATCGCCAAACTGCAGGACTAACCGAT
AGGATTAACTGAAAGCGATT

Downstream 100 bases:

>100_bases
CATTATGTTTACAGGTATTGTTGAAGCGGTTGGCAAGCTGACCGCTATTATCCCTAAAGGCAGCGACGTCACCATCAGTG
TAGATGTGGGTAAGCTGGAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MPMFTSFDHQMMSRAIELAWRGRFTTSPNPNVGCVITRGEQIVGEGFHFRAGEPHAEVHAMRQAGELTRGATAYVTLEPC
SHYGRTPPCAEGLIKAGVAKVICAMQDPNPQVAGKGVQMLRDAGIEVEVGLLEADARVLNRGFLKRMETGMPFVQLKMAA
SLDGQTALANGKSQWITSPAARKDVQRFRAQASAILSTSQTVLADNASLAVRWYDLPSSVQAQYAEADLRQPLRVILDRQ
HQLHPELALYQTPSPVLRVASENAELCISAENGKLDLRELLALLAQQHNVNQLWVEAGSQLAQSLIEQKLVDEIILYLAP
KLMGSDGRGLFGALGLTEMAEAIELKIEDCRMVGADLRIIATPKTKD

Sequences:

>Translated_367_residues
MPMFTSFDHQMMSRAIELAWRGRFTTSPNPNVGCVITRGEQIVGEGFHFRAGEPHAEVHAMRQAGELTRGATAYVTLEPC
SHYGRTPPCAEGLIKAGVAKVICAMQDPNPQVAGKGVQMLRDAGIEVEVGLLEADARVLNRGFLKRMETGMPFVQLKMAA
SLDGQTALANGKSQWITSPAARKDVQRFRAQASAILSTSQTVLADNASLAVRWYDLPSSVQAQYAEADLRQPLRVILDRQ
HQLHPELALYQTPSPVLRVASENAELCISAENGKLDLRELLALLAQQHNVNQLWVEAGSQLAQSLIEQKLVDEIILYLAP
KLMGSDGRGLFGALGLTEMAEAIELKIEDCRMVGADLRIIATPKTKD
>Mature_366_residues
PMFTSFDHQMMSRAIELAWRGRFTTSPNPNVGCVITRGEQIVGEGFHFRAGEPHAEVHAMRQAGELTRGATAYVTLEPCS
HYGRTPPCAEGLIKAGVAKVICAMQDPNPQVAGKGVQMLRDAGIEVEVGLLEADARVLNRGFLKRMETGMPFVQLKMAAS
LDGQTALANGKSQWITSPAARKDVQRFRAQASAILSTSQTVLADNASLAVRWYDLPSSVQAQYAEADLRQPLRVILDRQH
QLHPELALYQTPSPVLRVASENAELCISAENGKLDLRELLALLAQQHNVNQLWVEAGSQLAQSLIEQKLVDEIILYLAPK
LMGSDGRGLFGALGLTEMAEAIELKIEDCRMVGADLRIIATPKTKD

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=359, Percent_Identity=54.874651810585, Blast_Score=398, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6319629, Length=188, Percent_Identity=26.063829787234, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40105; Mature: 39973

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMFTSFDHQMMSRAIELAWRGRFTTSPNPNVGCVITRGEQIVGEGFHFRAGEPHAEVHA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHCCCCEECCCCCHHHHHH
MRQAGELTRGATAYVTLEPCSHYGRTPPCAEGLIKAGVAKVICAMQDPNPQVAGKGVQML
HHHHHHHCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
RDAGIEVEVGLLEADARVLNRGFLKRMETGMPFVQLKMAASLDGQTALANGKSQWITSPA
HHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCHHHCCCHH
ARKDVQRFRAQASAILSTSQTVLADNASLAVRWYDLPSSVQAQYAEADLRQPLRVILDRQ
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCH
HQLHPELALYQTPSPVLRVASENAELCISAENGKLDLRELLALLAQQHNVNQLWVEAGSQ
HHCCCCEEEECCCCHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
LAQSLIEQKLVDEIILYLAPKLMGSDGRGLFGALGLTEMAEAIELKIEDCRMVGADLRII
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHEEECCCEEEE
ATPKTKD
ECCCCCC
>Mature Secondary Structure 
PMFTSFDHQMMSRAIELAWRGRFTTSPNPNVGCVITRGEQIVGEGFHFRAGEPHAEVHA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHCCCCEECCCCCHHHHHH
MRQAGELTRGATAYVTLEPCSHYGRTPPCAEGLIKAGVAKVICAMQDPNPQVAGKGVQML
HHHHHHHCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
RDAGIEVEVGLLEADARVLNRGFLKRMETGMPFVQLKMAASLDGQTALANGKSQWITSPA
HHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCHHHCCCHH
ARKDVQRFRAQASAILSTSQTVLADNASLAVRWYDLPSSVQAQYAEADLRQPLRVILDRQ
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCH
HQLHPELALYQTPSPVLRVASENAELCISAENGKLDLRELLALLAQQHNVNQLWVEAGSQ
HHCCCCEEEECCCCHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
LAQSLIEQKLVDEIILYLAPKLMGSDGRGLFGALGLTEMAEAIELKIEDCRMVGADLRII
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHEEECCCEEEE
ATPKTKD
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]