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The map label for this gene is yaeL [C]

Identifier: 227082377

GI number: 227082377

Start: 2345584

End: 2346942

Strand: Reverse

Name: yaeL [C]

Synonym: VCM66_2176

Alternate gene names: 227082377

Gene position: 2346942-2345584 (Counterclockwise)

Preceding gene: 227082378

Following gene: 227082376

Centisome position: 81.14

GC content: 48.64

Gene sequence:

>1359_bases
ATGACCGACATATTGTGGAACTTTATCGCCTTCATCATTGCGCTGGGCATTCTCGTCGCAGTGCATGAGTTCGGACACTT
CTGGGTTGCCAGACGTTGCGGTGTGAAAGTTGAGAAATTTTCTATCGGTTTTGGGAAATCGATTTGGAAACGCGTCGGCC
ATGACGGTACAGAATACTCGATATCGATGATCCCACTCGGTGGTTACGTCAAAATGCTCGATGGACGTGTGGATGATGTT
CCCGCCGAACAGCAAGCCATGGCGTTTGATAAGCAGTCACTCTGGAAACGTTCTGCCATTGTGAGTGCGGGCCCCATTTT
TAACTTCCTCTTCGCAATCTTTGCCTATTGGCTGGTGTTTATGATCGGCGTACCAGCGGTCAAGCCTGTGATTGGCGAAG
TGACACCCTACTCGATTGCGGCTCAAGCGGGCCTTGAGCCGGGTATGGAGATCAAAGCGGTTTCTGGCGTGAATACTCCC
GACTGGGAATCGGTCAACATGGGCTTAATTGGTCATATTGGCGATGACAGTATGACGATCACCGTCTCCTCCGCCGAAGG
GGTGGGATTGAATGAAATTAAGACAATAAATCTGCGTGATTGGAACTTTGACCCAGAAACAGAGTCTGCTATGGGGGCGC
TTGGCTTTAAACCTTTTACCCCTGAGATTTCCAATCAGCTGACCAATGTTTCTGCGCAAGGTGCGGGTGAGCGTGCGGGT
TTACAAGTCGGTGATACCGTGTTGCAAATCAATGGACAAGCGGTTGAGGCTTGGCAACAAGTGGTCAATGCAATTCAAAG
TCATCCTAACGCGCCTATCGCAGTTATGGTTGAGCGAGCAGGCCAGCAAGTTGAACTCACTTTGATTCCCGATAGCCGTG
AGCTTTCGCAAGGAAAAGTGATTGGTTTTGCGGGAATCGCACCAAAAGTCGCAGAATGGCCGCAAAACTATCGATTTGAA
TTGCAATTTGGTGTATTTGAGTCGCTTGGTAAAGCGGTTGAAAAAAGCGGACAAGTGATTGACCTGACGGTCAGCATGTT
GAAAAAACTGTTGGTGGGCGATGTTGGGTTGAATAATCTCAGTGGTCCCATTTCGATTGCTAAAGGCGCAGGAACAACGG
CTGACTACGGCTTTGTGTACTTTTTAGGCTTTTTGGCTCTGATCAGTATTAACCTTGGCATTATCAACTTGGTGCCACTG
CCGATGCTGGATGGTGGTCATCTGTTGTTTTTCATGATTGAAGCGGTGATCCGTCGCCCTGTTCCGGAAAAGGTGCAGGA
AATGGGTTACCGGATTGGTGGTGCCATCATTTTCTCTTTAATGGCCGTTGCAATCTTTAACGATTTTACTCGCCTGTGA

Upstream 100 bases:

>100_bases
CGACCAACACCCAGTTACATTGCCGTGACTTGGAAAGCCTGCTTGAGCTAGATACAATGGCTCGGCATTTTGCCCATCAA
GTACTCAAAGAGCGCCAAGC

Downstream 100 bases:

>100_bases
TTGATAAACATTAGGCAAGAGTTGCAGTAAGGAAGAACTCAAAACAATATGGCGATGAAACAGATTCTGCTCGCGACACT
GCTTGCCACGAGCGTGTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDV
PAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTP
DWESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFE
LQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPL
PMLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTRL

Sequences:

>Translated_452_residues
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDV
PAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTP
DWESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFE
LQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPL
PMLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTRL
>Mature_451_residues
TDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDVP
AEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPD
WESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAGL
QVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFEL
QFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLP
MLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=452, Percent_Identity=53.3185840707965, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2253_VIBCH (Q9KPV9)

Other databases:

- EMBL:   AE003852
- PIR:   C82099
- RefSeq:   NP_231884.1
- ProteinModelPortal:   Q9KPV9
- SMR:   Q9KPV9
- MEROPS:   M50.004
- GeneID:   2613175
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC2253
- TIGR:   VC_2253
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- ProtClustDB:   CLSK874734
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 48983; Mature: 48851

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 23-23

Signals:

None

Transmembrane regions:

HASH(0x280fa42c)-; HASH(0x27ed82f8)-; HASH(0x27caf730)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
ISMIPLGGYVKMLDGRVDDVPAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVF
EEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPDWESVNMGLIGHIGDDSMTI
HHCCCHHHHHHCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
TVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
EEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKV
CEECCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCE
IGFAGIAPKVAEWPQNYRFELQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNL
EEEECCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLPMLDGGHLLFFMIEAVIRRP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
VPEKVQEMGYRIGGAIIFSLMAVAIFNDFTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
ISMIPLGGYVKMLDGRVDDVPAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVF
EEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPDWESVNMGLIGHIGDDSMTI
HHCCCHHHHHHCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
TVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
EEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKV
CEECCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCE
IGFAGIAPKVAEWPQNYRFELQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNL
EEEECCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLPMLDGGHLLFFMIEAVIRRP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
VPEKVQEMGYRIGGAIIFSLMAVAIFNDFTRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301