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The map label for this gene is yciA [H]

Identifier: 227081850

GI number: 227081850

Start: 1780723

End: 1781163

Strand: Direct

Name: yciA [H]

Synonym: VCM66_1641

Alternate gene names: 227081850

Gene position: 1780723-1781163 (Clockwise)

Preceding gene: 227081849

Following gene: 227081851

Centisome position: 61.56

GC content: 48.53

Gene sequence:

>441_bases
TTGTTTGCTGTGGATCCCCAAATGAATCAAACCGTAAATTCACCTAAAGGCCAGCTTCTGCTGCGCACACTCGCAATGCC
TGCCGATACGAATGCAAATGGCGATATTTTTGGCGGCTGGATCATGTCTCAACTCGACTTAGCGGGCGGTATTCTCGCTA
AAGAGATCTCCTGTGGACGCATCGTGACTGTTTCTGTTTCCAGTATCACTTTTAAAAAACCTGTCAAAGTCGGTGACGTG
GTATGTTGCTACGGCGAATGCACCAAGATTGGCCGCACATCGATGTCGATCAATCTCGAAGTGTGGGTTAAGCCGGTCAA
AGAAGAGGGGGTCGGCGAACGTTTTCAAGTGTGTGAAGCCACCTTTAACTATGTGGCGATTGATGCAAATGGCCGCCCCA
GAGCAATAAGCCTCAGCAATGGATCACAGAAATCATCTTGA

Upstream 100 bases:

>100_bases
AAGCAGGAAGGAGATTGGCTGGGTATAAAGGGATGATCCAGTGACGAATTTGTGGTTATAATCCGCCCCTAATCCACAGC
GACCGTATTCGGTCGCTGTT

Downstream 100 bases:

>100_bases
TAGGCTGTGTTTCACAAGCGAGTTGCGTAGAGTATTGACTTTGCTTTTGGTCAGTTGATAAGGATTAAAGTGTTATGTGG
TATGTGATTTTTGCGCAGGA

Product: Acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MFAVDPQMNQTVNSPKGQLLLRTLAMPADTNANGDIFGGWIMSQLDLAGGILAKEISCGRIVTVSVSSITFKKPVKVGDV
VCCYGECTKIGRTSMSINLEVWVKPVKEEGVGERFQVCEATFNYVAIDANGRPRAISLSNGSQKSS

Sequences:

>Translated_146_residues
MFAVDPQMNQTVNSPKGQLLLRTLAMPADTNANGDIFGGWIMSQLDLAGGILAKEISCGRIVTVSVSSITFKKPVKVGDV
VCCYGECTKIGRTSMSINLEVWVKPVKEEGVGERFQVCEATFNYVAIDANGRPRAISLSNGSQKSS
>Mature_146_residues
MFAVDPQMNQTVNSPKGQLLLRTLAMPADTNANGDIFGGWIMSQLDLAGGILAKEISCGRIVTVSVSSITFKKPVKVGDV
VCCYGECTKIGRTSMSINLEVWVKPVKEEGVGERFQVCEATFNYVAIDANGRPRAISLSNGSQKSS

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=132, Percent_Identity=62.1212121212121, Blast_Score=183, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 15661; Mature: 15661

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAVDPQMNQTVNSPKGQLLLRTLAMPADTNANGDIFGGWIMSQLDLAGGILAKEISCGR
CCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCEEEEECCCCE
IVTVSVSSITFKKPVKVGDVVCCYGECTKIGRTSMSINLEVWVKPVKEEGVGERFQVCEA
EEEEEECEEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHC
TFNYVAIDANGRPRAISLSNGSQKSS
CCCEEEECCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MFAVDPQMNQTVNSPKGQLLLRTLAMPADTNANGDIFGGWIMSQLDLAGGILAKEISCGR
CCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCEEEEECCCCE
IVTVSVSSITFKKPVKVGDVVCCYGECTKIGRTSMSINLEVWVKPVKEEGVGERFQVCEA
EEEEEECEEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHC
TFNYVAIDANGRPRAISLSNGSQKSS
CCCEEEECCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]