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The map label for this gene is yhdH [H]

Identifier: 227081820

GI number: 227081820

Start: 1747555

End: 1748901

Strand: Reverse

Name: yhdH [H]

Synonym: VCM66_1609

Alternate gene names: 227081820

Gene position: 1748901-1747555 (Counterclockwise)

Preceding gene: 227081823

Following gene: 227081819

Centisome position: 60.46

GC content: 46.92

Gene sequence:

>1347_bases
TTGGTAGCAAATATGGCAAGTGGTTCTAGAGGTCAGTTCACCTCTCGATTTGGATTTATTATGGCTGCAGCGGGTTCTGC
GGTGGGGCTTGGCAATGTGTGGGGCTTCCCAACTCAAGCTGCCAGTAATGGTGGTGCCGTTTTCCTTTTGGTTTATCTCT
GTATGGTCTTTCTTCTCGCTTACCCGATGTTGGTGGCGGAGTTAACCATTGGGCGTTATGGTCAATCTAACCCGATACGT
GCATTTCGCTCTGTTTGGCCGCAAGGCAAATGGGGTGCGATTTTGCTTGGTGTTATCGGCATGGTCGTGGTGTCACTTAT
CCTTAGCTTTTACGCCATCGTCGCAGGCTGGCTAGTTGGCTCCCTGTTTGGTAGTGGCTTAACGCTGATTGGTGCCGACA
GTGCAAGTCAGTGGCTAACCTCGTTCAGTACTGAGCGAAATCTCATTCTGATGGTGTCATTCATGGTATTGACCATGTTT
GTGGTGCGTAACGGTGTCGCTAACGGGATTGAAAAATGGTCTACCCGTTTAATGCCACTGCTATTTGTTTTGTTTGGTTT
ACTGACGGTGTACATCTTCACTCAAGAGGGTGCTCTGGATGGACTCAAAATGTATCTGGTACCAGATTTGAGCCACTTTA
CGCCTGATGTTGTGGTTAGTGCGATGGGACAAGCCTTCTTCTCACTATCACTGGGTGTATGCGTGATGACCACTTATGGC
TCATACCTCAACAAAGAAGCAAATTTGCCGAAAACTGCAGCACAAGTGGCTTTGATTGATACTGGTGTCGCCTTCATTGC
TGGCTTGATGGTACTGCCTGCCATGTTTGTTGCGAAACACAACGGTGTGGAGATTTTCTCTTCATCTGGTGAGTTACTCA
ATTCTGATACCTTAGTCTTTACCGTGTTACCTGCGATGTTTGACACCATGGGGGCGGTAGGTGCTGTGATTGGTATTATC
TTCTTCCTTTTGATGATCATTGCCGCATTGACTTCTTCCATTTCTATGTTGGAAGTGCCCGTCGCTTGCGCAGTGGAAGA
GTTACAGCAGAAACGATCTAGTGCGGTGTTATGGATTGGCGGTTTGGTCACGATCATTTCAGGTGTGATTGTGCTGAATT
TTTCCAGCTTGTTTGGTTTAGTGATTAATTTCACCACGGTTTACTCGCAACCGATCATCGCACTTTTGATTACCTTGATT
GCGGGTTGGATTTGGAATCGTAACCAGATCCTATCGGAGCTGAAACAAGGCTGCCCTGACATTGAAAACAGCCTATTTTG
GAAAATCTGGCCTTGGTATGTGCGTCTTGTCTGCCCGGTTCTGATGTTGATGGTGTTTTTCGCTTAA

Upstream 100 bases:

>100_bases
TTGAACTGATTTACTTGCCATACTTACAAAGTTAGTGATGATTTTGTCATGTGTAATTTTATTTTTACACCTACAATCAT
AAGCAAACAAACACAATTCA

Downstream 100 bases:

>100_bases
GTAACCTGAGTAACAGAACTTTGCAGATAAAGCGGCTTTTCAGCCGCTTTATCTTTTGGTTTTGGGTATATAATCACGCC
GCAAAGTGAGGCGTATTTAT

Product: putative sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MVANMASGSRGQFTSRFGFIMAAAGSAVGLGNVWGFPTQAASNGGAVFLLVYLCMVFLLAYPMLVAELTIGRYGQSNPIR
AFRSVWPQGKWGAILLGVIGMVVVSLILSFYAIVAGWLVGSLFGSGLTLIGADSASQWLTSFSTERNLILMVSFMVLTMF
VVRNGVANGIEKWSTRLMPLLFVLFGLLTVYIFTQEGALDGLKMYLVPDLSHFTPDVVVSAMGQAFFSLSLGVCVMTTYG
SYLNKEANLPKTAAQVALIDTGVAFIAGLMVLPAMFVAKHNGVEIFSSSGELLNSDTLVFTVLPAMFDTMGAVGAVIGII
FFLLMIIAALTSSISMLEVPVACAVEELQQKRSSAVLWIGGLVTIISGVIVLNFSSLFGLVINFTTVYSQPIIALLITLI
AGWIWNRNQILSELKQGCPDIENSLFWKIWPWYVRLVCPVLMLMVFFA

Sequences:

>Translated_448_residues
MVANMASGSRGQFTSRFGFIMAAAGSAVGLGNVWGFPTQAASNGGAVFLLVYLCMVFLLAYPMLVAELTIGRYGQSNPIR
AFRSVWPQGKWGAILLGVIGMVVVSLILSFYAIVAGWLVGSLFGSGLTLIGADSASQWLTSFSTERNLILMVSFMVLTMF
VVRNGVANGIEKWSTRLMPLLFVLFGLLTVYIFTQEGALDGLKMYLVPDLSHFTPDVVVSAMGQAFFSLSLGVCVMTTYG
SYLNKEANLPKTAAQVALIDTGVAFIAGLMVLPAMFVAKHNGVEIFSSSGELLNSDTLVFTVLPAMFDTMGAVGAVIGII
FFLLMIIAALTSSISMLEVPVACAVEELQQKRSSAVLWIGGLVTIISGVIVLNFSSLFGLVINFTTVYSQPIIALLITLI
AGWIWNRNQILSELKQGCPDIENSLFWKIWPWYVRLVCPVLMLMVFFA
>Mature_448_residues
MVANMASGSRGQFTSRFGFIMAAAGSAVGLGNVWGFPTQAASNGGAVFLLVYLCMVFLLAYPMLVAELTIGRYGQSNPIR
AFRSVWPQGKWGAILLGVIGMVVVSLILSFYAIVAGWLVGSLFGSGLTLIGADSASQWLTSFSTERNLILMVSFMVLTMF
VVRNGVANGIEKWSTRLMPLLFVLFGLLTVYIFTQEGALDGLKMYLVPDLSHFTPDVVVSAMGQAFFSLSLGVCVMTTYG
SYLNKEANLPKTAAQVALIDTGVAFIAGLMVLPAMFVAKHNGVEIFSSSGELLNSDTLVFTVLPAMFDTMGAVGAVIGII
FFLLMIIAALTSSISMLEVPVACAVEELQQKRSSAVLWIGGLVTIISGVIVLNFSSLFGLVINFTTVYSQPIIALLITLI
AGWIWNRNQILSELKQGCPDIENSLFWKIWPWYVRLVCPVLMLMVFFA

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=479, Percent_Identity=22.5469728601253, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184408, Length=398, Percent_Identity=25.6281407035176, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI171184406, Length=398, Percent_Identity=25.6281407035176, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI171184404, Length=398, Percent_Identity=25.6281407035176, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI197276623, Length=334, Percent_Identity=26.6467065868263, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI54607094, Length=334, Percent_Identity=26.6467065868263, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI7657587, Length=395, Percent_Identity=24.5569620253165, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI5032097, Length=335, Percent_Identity=28.955223880597, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4507043, Length=467, Percent_Identity=22.0556745182013, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI289191351, Length=407, Percent_Identity=23.8329238329238, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557046, Length=407, Percent_Identity=23.8329238329238, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI289191377, Length=407, Percent_Identity=23.8329238329238, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI134304856, Length=443, Percent_Identity=22.3476297968397, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507041, Length=495, Percent_Identity=23.4343434343434, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI58219014, Length=305, Percent_Identity=23.9344262295082, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI218563756, Length=335, Percent_Identity=27.4626865671642, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI188528618, Length=411, Percent_Identity=23.6009732360097, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=22.9508196721311, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI92859670, Length=153, Percent_Identity=28.7581699346405, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI11181770, Length=301, Percent_Identity=25.9136212624585, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI197276625, Length=149, Percent_Identity=30.2013422818792, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=464, Percent_Identity=26.2931034482759, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535731, Length=112, Percent_Identity=38.3928571428571, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=116, Percent_Identity=35.3448275862069, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=115, Percent_Identity=33.0434782608696, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212642127, Length=102, Percent_Identity=35.2941176470588, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24762620, Length=506, Percent_Identity=25.6916996047431, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24661428, Length=497, Percent_Identity=24.1448692152917, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24652942, Length=491, Percent_Identity=22.1995926680244, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45551088, Length=491, Percent_Identity=22.1995926680244, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17136952, Length=375, Percent_Identity=23.7333333333333, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24654186, Length=307, Percent_Identity=25.4071661237785, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364394, Length=375, Percent_Identity=23.7333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574704, Length=375, Percent_Identity=23.7333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136950, Length=375, Percent_Identity=23.7333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574702, Length=375, Percent_Identity=23.7333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639514, Length=301, Percent_Identity=26.9102990033223, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639516, Length=301, Percent_Identity=26.9102990033223, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221329674, Length=301, Percent_Identity=26.9102990033223, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364136, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582567, Length=324, Percent_Identity=23.4567901234568, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48393; Mature: 48393

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00141 ASP_PROTEASE ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVANMASGSRGQFTSRFGFIMAAAGSAVGLGNVWGFPTQAASNGGAVFLLVYLCMVFLLA
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
YPMLVAELTIGRYGQSNPIRAFRSVWPQGKWGAILLGVIGMVVVSLILSFYAIVAGWLVG
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFGSGLTLIGADSASQWLTSFSTERNLILMVSFMVLTMFVVRNGVANGIEKWSTRLMPL
HHHHCCCEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVLFGLLTVYIFTQEGALDGLKMYLVPDLSHFTPDVVVSAMGQAFFSLSLGVCVMTTYG
HHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SYLNKEANLPKTAAQVALIDTGVAFIAGLMVLPAMFVAKHNGVEIFSSSGELLNSDTLVF
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHH
TVLPAMFDTMGAVGAVIGIIFFLLMIIAALTSSISMLEVPVACAVEELQQKRSSAVLWIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEHHH
GLVTIISGVIVLNFSSLFGLVINFTTVYSQPIIALLITLIAGWIWNRNQILSELKQGCPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
IENSLFWKIWPWYVRLVCPVLMLMVFFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]