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The map label for this gene is sdaC-2 [H]

Identifier: 227081808

GI number: 227081808

Start: 1736738

End: 1737991

Strand: Direct

Name: sdaC-2 [H]

Synonym: VCM66_1597

Alternate gene names: 227081808

Gene position: 1736738-1737991 (Clockwise)

Preceding gene: 227081806

Following gene: 227081809

Centisome position: 60.04

GC content: 47.85

Gene sequence:

>1254_bases
GTGAAAGACTCTCAGGAAGTGACCCATTTTAGTGCTGCCCGTTCCTCAAAATGGACTCAACATGATACCTATTGGTTACT
AAGCCTATTTGGTACAGCAGTAGGTGCAGGGATTTTATTTTTACCGATCAATATTGGCTTAGGGGGATTCTGGCCGCTGG
TGCTGATGGCAGTATTAGCCTTTCCTATGACCTATCTGTCCCACCGTGGACTGGCGCGTTTTGTACTTTCATCACGTCGC
CCAAATGCCGATTTTACTGATGTGGTCGAAGAGCACTTTGGCCAAAATGCTGGACGATTGATTTCCCTACTCTATTTTTT
ATCGATTTTTCCTATTCTGCTTATCTACGGTGTTGGCCTTACCAACACAGTCGATAGTTTCTTGGTTAACCAAGCGGACA
TGGTATCGCCGCCACGCGCACTACTTTCTGGTGCTTTAGTGTTTGGGCTTATCGCTATCATGCTCAGTGGCGAGAAAATC
ATGCTGCGCGCTTTTGCCATCATGGTTTATCCGCTGGCGGCGATCCTTGCCCTACTCTCGCTGTATTTGATCCCTTACTG
GTCAATGCCTTCGTTTGATTTTCCGCAAACCAGCGATTTTCTGCACACTGTATGGCTGGCCGTACCGGTAGTGGTGTTCT
CATTCAGCCATGCTGCGGCCATTTCAAGTTTTGCCAATATCCAGCGTCGTCATTATGGTGAACAAGCTGATCAAAAGTCT
GAGCAGATTCTGCGCCACACTAGCGTGGTCTTAATTTTGTTTGTGTTGTTGTTTGTCTTCTCTTGTGTACTTGCCCTTTC
GCCACAAGCACTGCAAGAAGCCAAAGCACAAAACATTTCGGTGCTGACTTATCTGGCCAATGTCACTGACAACCCATTTA
TCGCGACGCTCGGGCCTCTGGTCGCCTTCATCGCCATCACCTCTTCCTTCCTCGGCCACTTCTTAGGGGCGCGTGAAAGT
TTATCTGGCCTACTGACCAAAAACTTAGGGGTATCACTACGTTTGGCGGAACGTCTCACCATCGGCTTTTTATTTGTCAC
CATCTGGATCGCTGCAATCCTCAACCCAAGCATTTTGGGCATGATGGAAGCGCTTTCTGGTCCAGTCATCGCAATGATTC
TATTCATAATGCCGATGATTGCCGTCTTCAAAGTGCCCGCCCTGCGTGAACATCAAAAACGTTTCAGCACTTTCTTCGTG
TTACTGGTTGGATTGCTCGCCGTTTCTGCTCTGCTCTACAGTTTACTTCGCTAA

Upstream 100 bases:

>100_bases
CGGAAAATTCCAGTGATTATGACCAGTATCGCAAAATGATCATAACCACTAATAGGAGTAGGATTCGCCACATTATTATT
TTTAGAGAAGTGAGATTTCA

Downstream 100 bases:

>100_bases
ATTTCCTGCGCTATTGGCTCCCAGCTGGGAGCCAAATTCCACACTGCCTCATTTCTGATGAATAAATCCAGTTCAACCTG
TCACAGAGTTGGCCAATAAT

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKDSQEVTHFSAARSSKWTQHDTYWLLSLFGTAVGAGILFLPINIGLGGFWPLVLMAVLAFPMTYLSHRGLARFVLSSRR
PNADFTDVVEEHFGQNAGRLISLLYFLSIFPILLIYGVGLTNTVDSFLVNQADMVSPPRALLSGALVFGLIAIMLSGEKI
MLRAFAIMVYPLAAILALLSLYLIPYWSMPSFDFPQTSDFLHTVWLAVPVVVFSFSHAAAISSFANIQRRHYGEQADQKS
EQILRHTSVVLILFVLLFVFSCVLALSPQALQEAKAQNISVLTYLANVTDNPFIATLGPLVAFIAITSSFLGHFLGARES
LSGLLTKNLGVSLRLAERLTIGFLFVTIWIAAILNPSILGMMEALSGPVIAMILFIMPMIAVFKVPALREHQKRFSTFFV
LLVGLLAVSALLYSLLR

Sequences:

>Translated_417_residues
MKDSQEVTHFSAARSSKWTQHDTYWLLSLFGTAVGAGILFLPINIGLGGFWPLVLMAVLAFPMTYLSHRGLARFVLSSRR
PNADFTDVVEEHFGQNAGRLISLLYFLSIFPILLIYGVGLTNTVDSFLVNQADMVSPPRALLSGALVFGLIAIMLSGEKI
MLRAFAIMVYPLAAILALLSLYLIPYWSMPSFDFPQTSDFLHTVWLAVPVVVFSFSHAAAISSFANIQRRHYGEQADQKS
EQILRHTSVVLILFVLLFVFSCVLALSPQALQEAKAQNISVLTYLANVTDNPFIATLGPLVAFIAITSSFLGHFLGARES
LSGLLTKNLGVSLRLAERLTIGFLFVTIWIAAILNPSILGMMEALSGPVIAMILFIMPMIAVFKVPALREHQKRFSTFFV
LLVGLLAVSALLYSLLR
>Mature_417_residues
MKDSQEVTHFSAARSSKWTQHDTYWLLSLFGTAVGAGILFLPINIGLGGFWPLVLMAVLAFPMTYLSHRGLARFVLSSRR
PNADFTDVVEEHFGQNAGRLISLLYFLSIFPILLIYGVGLTNTVDSFLVNQADMVSPPRALLSGALVFGLIAIMLSGEKI
MLRAFAIMVYPLAAILALLSLYLIPYWSMPSFDFPQTSDFLHTVWLAVPVVVFSFSHAAAISSFANIQRRHYGEQADQKS
EQILRHTSVVLILFVLLFVFSCVLALSPQALQEAKAQNISVLTYLANVTDNPFIATLGPLVAFIAITSSFLGHFLGARES
LSGLLTKNLGVSLRLAERLTIGFLFVTIWIAAILNPSILGMMEALSGPVIAMILFIMPMIAVFKVPALREHQKRFSTFFV
LLVGLLAVSALLYSLLR

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=427, Percent_Identity=51.288056206089, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1789504, Length=433, Percent_Identity=38.3371824480369, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789211, Length=411, Percent_Identity=35.2798053527981, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1789961, Length=402, Percent_Identity=25.8706467661692, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI145693183, Length=410, Percent_Identity=26.3414634146341, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 45893; Mature: 45893

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSQEVTHFSAARSSKWTQHDTYWLLSLFGTAVGAGILFLPINIGLGGFWPLVLMAVLA
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHH
FPMTYLSHRGLARFVLSSRRPNADFTDVVEEHFGQNAGRLISLLYFLSIFPILLIYGVGL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
TNTVDSFLVNQADMVSPPRALLSGALVFGLIAIMLSGEKIMLRAFAIMVYPLAAILALLS
HHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LYLIPYWSMPSFDFPQTSDFLHTVWLAVPVVVFSFSHAAAISSFANIQRRHYGEQADQKS
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EQILRHTSVVLILFVLLFVFSCVLALSPQALQEAKAQNISVLTYLANVTDNPFIATLGPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
VAFIAITSSFLGHFLGARESLSGLLTKNLGVSLRLAERLTIGFLFVTIWIAAILNPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MMEALSGPVIAMILFIMPMIAVFKVPALREHQKRFSTFFVLLVGLLAVSALLYSLLR
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKDSQEVTHFSAARSSKWTQHDTYWLLSLFGTAVGAGILFLPINIGLGGFWPLVLMAVLA
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHH
FPMTYLSHRGLARFVLSSRRPNADFTDVVEEHFGQNAGRLISLLYFLSIFPILLIYGVGL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
TNTVDSFLVNQADMVSPPRALLSGALVFGLIAIMLSGEKIMLRAFAIMVYPLAAILALLS
HHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LYLIPYWSMPSFDFPQTSDFLHTVWLAVPVVVFSFSHAAAISSFANIQRRHYGEQADQKS
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EQILRHTSVVLILFVLLFVFSCVLALSPQALQEAKAQNISVLTYLANVTDNPFIATLGPL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
VAFIAITSSFLGHFLGARESLSGLLTKNLGVSLRLAERLTIGFLFVTIWIAAILNPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MMEALSGPVIAMILFIMPMIAVFKVPALREHQKRFSTFFVLLVGLLAVSALLYSLLR
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]