Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 227081721

GI number: 227081721

Start: 1627028

End: 1628305

Strand: Direct

Name: macB [H]

Synonym: VCM66_1507

Alternate gene names: 227081721

Gene position: 1627028-1628305 (Clockwise)

Preceding gene: 227081720

Following gene: 227081722

Centisome position: 56.25

GC content: 50.7

Gene sequence:

>1278_bases
ATGTTGCCAATAAGACAAATTATGCAGGAAATGGCGGCCGAAAAGCTCAGATTGAGCCTCACTATTTTGGCCGTTGCGTG
GTCAACCTTATGTATCGCAGGGTTACTTGCGGTCGGTGAAGGGATCCGCAGTGGAATTGTACGCACCATCCAAAATGGCA
ATGGTAACCTGATTCATGTCAGCGGCGGTTATGCCACGCAAACCCATGGCCGTTTTCATGAGGGGCAAGCGCTTTCTCTC
ACCGAGCAAGATAGCCAAGTCTTGGCCGCTCTGCCTATGGTCAAACACGCACTTCCTTCGGCCGAGTGGCAAGAGCTGAT
CACGTTTGCAGATAAGCGTTCATGGATGATGCCTTACGCGGTCAAAAGTGAGTATCAGGCGATGAATAAACTGCGCTTGT
TACCCGGCGGGCGCTGGTTTAATCCCGTTGATGAAACACAGCAACGTAAAGTGGTCGTGCTCGGTTATCAACTCGCGGTA
CAACTGTTTAATCAGCAAGAGGGCGACTGGTTTAGCGGCGGCGAATTAGAGCAAGATCCTGTCGGTCAGATTGCCAAAAT
AGGCGCACACGAATTTACGGTGATCGGAGTGCTGGCCAAAAACAGCGGCAACATTGAGCAGGGTTCACCTATTGATTACA
GTGGTTTTACGCCATTCAGTACTTGGCAGCGTTTTCACCCCAACCAAGCGATCAGCGGAATTAACCTTGAACCGAGGGTG
GGCAGTGACCGTCAAGCGTTGGCAGCCACGGTACAGCAAGTGTTAAAACGCAAATACGCCGCCAGCTTGCAAGATCAGCA
AATTGTCATGGTGCAAGACCACTTTTTGAGCCAGAAAAGTATGCAGCAGTTTCTGCTGAGACTACAAAGCTTCCTTGGCA
TTATTGGGTTTATCACTTTAGCCGTGGCAAGTTTAGGCATTACCAATGTGATGTTTGCTACCGTGAAGCGGGCCACACGC
GACATTGGCGTACGCATGGCCGTAGGTGCAACCCCCAATACCATTCGCTGCCACTATTTGGCTCAATCTTTGATCACCAT
GGGCATGGGAGGAATTGCCGGCTTAGGTGTGACATTTGCGATGGTTCGCCTACTCGCCGCCATTCCTTTACAGGGCAATC
CGATTTATGACCACTTAGGCCAACCGGTTCCAGAGCTGTCGCTTAGCGTCATTGTGATAGTGATTGTCACCATTACCGTG
ATGGGCATTGTTGCGGCGTGGTTGCCAGCCAACCATGCGGCGAAAGTGACACCGTTACAAGCATTACAGAGTGAATAA

Upstream 100 bases:

>100_bases
GTTGGTGACCAGCATTTTAGCCTTAGCGGCGGCCTACTTCCCAGCTCGCAGAGCGGCGCAATTAGAGCCCGTCATTGCGC
TCAGTAGTCGGAGTTAATGC

Downstream 100 bases:

>100_bases
TGAAGTCTTTATCTCCTGCTCCTTTGGTGGAGCTACAGCAAATTTGTAAACATTACACCAGTGGGCAAAACGTGGTTAAA
GCGCTTGATGGCGTCGACTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLPIRQIMQEMAAEKLRLSLTILAVAWSTLCIAGLLAVGEGIRSGIVRTIQNGNGNLIHVSGGYATQTHGRFHEGQALSL
TEQDSQVLAALPMVKHALPSAEWQELITFADKRSWMMPYAVKSEYQAMNKLRLLPGGRWFNPVDETQQRKVVVLGYQLAV
QLFNQQEGDWFSGGELEQDPVGQIAKIGAHEFTVIGVLAKNSGNIEQGSPIDYSGFTPFSTWQRFHPNQAISGINLEPRV
GSDRQALAATVQQVLKRKYAASLQDQQIVMVQDHFLSQKSMQQFLLRLQSFLGIIGFITLAVASLGITNVMFATVKRATR
DIGVRMAVGATPNTIRCHYLAQSLITMGMGGIAGLGVTFAMVRLLAAIPLQGNPIYDHLGQPVPELSLSVIVIVIVTITV
MGIVAAWLPANHAAKVTPLQALQSE

Sequences:

>Translated_425_residues
MLPIRQIMQEMAAEKLRLSLTILAVAWSTLCIAGLLAVGEGIRSGIVRTIQNGNGNLIHVSGGYATQTHGRFHEGQALSL
TEQDSQVLAALPMVKHALPSAEWQELITFADKRSWMMPYAVKSEYQAMNKLRLLPGGRWFNPVDETQQRKVVVLGYQLAV
QLFNQQEGDWFSGGELEQDPVGQIAKIGAHEFTVIGVLAKNSGNIEQGSPIDYSGFTPFSTWQRFHPNQAISGINLEPRV
GSDRQALAATVQQVLKRKYAASLQDQQIVMVQDHFLSQKSMQQFLLRLQSFLGIIGFITLAVASLGITNVMFATVKRATR
DIGVRMAVGATPNTIRCHYLAQSLITMGMGGIAGLGVTFAMVRLLAAIPLQGNPIYDHLGQPVPELSLSVIVIVIVTITV
MGIVAAWLPANHAAKVTPLQALQSE
>Mature_425_residues
MLPIRQIMQEMAAEKLRLSLTILAVAWSTLCIAGLLAVGEGIRSGIVRTIQNGNGNLIHVSGGYATQTHGRFHEGQALSL
TEQDSQVLAALPMVKHALPSAEWQELITFADKRSWMMPYAVKSEYQAMNKLRLLPGGRWFNPVDETQQRKVVVLGYQLAV
QLFNQQEGDWFSGGELEQDPVGQIAKIGAHEFTVIGVLAKNSGNIEQGSPIDYSGFTPFSTWQRFHPNQAISGINLEPRV
GSDRQALAATVQQVLKRKYAASLQDQQIVMVQDHFLSQKSMQQFLLRLQSFLGIIGFITLAVASLGITNVMFATVKRATR
DIGVRMAVGATPNTIRCHYLAQSLITMGMGGIAGLGVTFAMVRLLAAIPLQGNPIYDHLGQPVPELSLSVIVIVIVTITV
MGIVAAWLPANHAAKVTPLQALQSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=423, Percent_Identity=25.7683215130024, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46329; Mature: 46329

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIRQIMQEMAAEKLRLSLTILAVAWSTLCIAGLLAVGEGIRSGIVRTIQNGNGNLIHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SGGYATQTHGRFHEGQALSLTEQDSQVLAALPMVKHALPSAEWQELITFADKRSWMMPYA
ECCCEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHH
VKSEYQAMNKLRLLPGGRWFNPVDETQQRKVVVLGYQLAVQLFNQQEGDWFSGGELEQDP
HHHHHHHHHHEEECCCCCCCCCCCHHHCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCH
VGQIAKIGAHEFTVIGVLAKNSGNIEQGSPIDYSGFTPFSTWQRFHPNQAISGINLEPRV
HHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
GSDRQALAATVQQVLKRKYAASLQDQQIVMVQDHFLSQKSMQQFLLRLQSFLGIIGFITL
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVASLGITNVMFATVKRATRDIGVRMAVGATPNTIRCHYLAQSLITMGMGGIAGLGVTFA
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
MVRLLAAIPLQGNPIYDHLGQPVPELSLSVIVIVIVTITVMGIVAAWLPANHAAKVTPLQ
HHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
ALQSE
HHCCC
>Mature Secondary Structure
MLPIRQIMQEMAAEKLRLSLTILAVAWSTLCIAGLLAVGEGIRSGIVRTIQNGNGNLIHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SGGYATQTHGRFHEGQALSLTEQDSQVLAALPMVKHALPSAEWQELITFADKRSWMMPYA
ECCCEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHH
VKSEYQAMNKLRLLPGGRWFNPVDETQQRKVVVLGYQLAVQLFNQQEGDWFSGGELEQDP
HHHHHHHHHHEEECCCCCCCCCCCHHHCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCH
VGQIAKIGAHEFTVIGVLAKNSGNIEQGSPIDYSGFTPFSTWQRFHPNQAISGINLEPRV
HHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
GSDRQALAATVQQVLKRKYAASLQDQQIVMVQDHFLSQKSMQQFLLRLQSFLGIIGFITL
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVASLGITNVMFATVKRATRDIGVRMAVGATPNTIRCHYLAQSLITMGMGGIAGLGVTFA
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
MVRLLAAIPLQGNPIYDHLGQPVPELSLSVIVIVIVTITVMGIVAAWLPANHAAKVTPLQ
HHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
ALQSE
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA