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The map label for this gene is macB2 [H]

Identifier: 227081720

GI number: 227081720

Start: 1625810

End: 1627024

Strand: Direct

Name: macB2 [H]

Synonym: VCM66_1506

Alternate gene names: 227081720

Gene position: 1625810-1627024 (Clockwise)

Preceding gene: 227081719

Following gene: 227081721

Centisome position: 56.21

GC content: 50.95

Gene sequence:

>1215_bases
ATGCGCCTCTTGTTACAGCAATCTTGGCAAACTTTGCTCGCTCATCGCCTGAAAAGCGTATTGGCGATCACCGCGATTAG
CTGGGGGGTGATTTCTGTGGTGATCTTGATGGCGCTCGGCGAAGGGTTTTATCGTGCTCAAACCGAATCCTTTCGCTTTC
TGTTGCAAGAAACACAAATGGTCGCCTCCGGCCAGACCAGCGAAGTGTGGCAAGGCATGCCTGCGAGACGCCCGATTCAA
CTGACCGAATCGTTAATGCGTGAAGTCGCACAACGTCCGGAGATCCAGCGTTACTCCATCGTCTATGAGAATCGAGAAGT
CTCCATCACCCAACAGCGAGGGACAGCGATTGGTAGTATGGTCAGTGGTGTGGATAGAGGGTATTTCTCTCTTGCTGGAT
TAAAACTCACCTTAGGTTCACGAGATTTCAGCCTTCATGATCAACACAACCACCGCCGTGTGGCCATTCTTGGCGATCAC
GTTGCAGCCACCAGCCAGCTTAAGATTGGAGATGAATTCAAAATTCGTGGCATCGCTTTTCGAGTGATTGGCATTATGGA
TGATGAAAGCAGCCGCTTTTCATTTGGTGATAACCAAAAAGTGTTTATTCCAAGCTCCACATTTAAAGACATTTGGGATA
CCCAACCGAACATGATGTTGGTACTGCCCGCACAAGGTGTTTCTAGCTGGGCGTTACGCGAGCAGTTACGTCACACTTTT
GCTCAGCGGTTACATTTCTCACCTGAGGATCAAGAGGCGGTCTTTCTCCCCGATTTCGGCAGTGGTGTTGCGGTGATCAC
TGCCATTTTACGAGGAATTCAAGCCTTTCTCGCCGCCAGTGGCATGATGACTATGGCTGTCGGCATCTTAGGCGTTGCCA
ATATGATGTTTTTAGCGGTGACCGAGCGTACGCGAGAAATCGGAGTACGTTTAGCCATTGGTGCTACACCGCAACGAATT
CAACAGCAGTTTTTATTAGAAGGATTGCTGCTGGTGGTCATCGGGGCGTTAGTCGGCTTACTGCTGGCCTACTTTGGCGT
GTTGCTGCTTAATCACCTTGGCCTACCCACGTGGCTTGGCGAGCCGGTGATCACTTCGACCACCGTCTGGCTTTCTATGT
TGGTGACCAGCATTTTAGCCTTAGCGGCGGCCTACTTCCCAGCTCGCAGAGCGGCGCAATTAGAGCCCGTCATTGCGCTC
AGTAGTCGGAGTTAA

Upstream 100 bases:

>100_bases
GTCGTTGGTATAGCTATTGGCGTCAGCGCATTGAGCTACTCAAATTAACAGGTCAGTTGAACGATAATGCCATCGCTCAG
CTTTCAGGAGCCTTTCGTTA

Downstream 100 bases:

>100_bases
TGCATGTTGCCAATAAGACAAATTATGCAGGAAATGGCGGCCGAAAAGCTCAGATTGAGCCTCACTATTTTGGCCGTTGC
GTGGTCAACCTTATGTATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRLLLQQSWQTLLAHRLKSVLAITAISWGVISVVILMALGEGFYRAQTESFRFLLQETQMVASGQTSEVWQGMPARRPIQ
LTESLMREVAQRPEIQRYSIVYENREVSITQQRGTAIGSMVSGVDRGYFSLAGLKLTLGSRDFSLHDQHNHRRVAILGDH
VAATSQLKIGDEFKIRGIAFRVIGIMDDESSRFSFGDNQKVFIPSSTFKDIWDTQPNMMLVLPAQGVSSWALREQLRHTF
AQRLHFSPEDQEAVFLPDFGSGVAVITAILRGIQAFLAASGMMTMAVGILGVANMMFLAVTERTREIGVRLAIGATPQRI
QQQFLLEGLLLVVIGALVGLLLAYFGVLLLNHLGLPTWLGEPVITSTTVWLSMLVTSILALAAAYFPARRAAQLEPVIAL
SSRS

Sequences:

>Translated_404_residues
MRLLLQQSWQTLLAHRLKSVLAITAISWGVISVVILMALGEGFYRAQTESFRFLLQETQMVASGQTSEVWQGMPARRPIQ
LTESLMREVAQRPEIQRYSIVYENREVSITQQRGTAIGSMVSGVDRGYFSLAGLKLTLGSRDFSLHDQHNHRRVAILGDH
VAATSQLKIGDEFKIRGIAFRVIGIMDDESSRFSFGDNQKVFIPSSTFKDIWDTQPNMMLVLPAQGVSSWALREQLRHTF
AQRLHFSPEDQEAVFLPDFGSGVAVITAILRGIQAFLAASGMMTMAVGILGVANMMFLAVTERTREIGVRLAIGATPQRI
QQQFLLEGLLLVVIGALVGLLLAYFGVLLLNHLGLPTWLGEPVITSTTVWLSMLVTSILALAAAYFPARRAAQLEPVIAL
SSRS
>Mature_404_residues
MRLLLQQSWQTLLAHRLKSVLAITAISWGVISVVILMALGEGFYRAQTESFRFLLQETQMVASGQTSEVWQGMPARRPIQ
LTESLMREVAQRPEIQRYSIVYENREVSITQQRGTAIGSMVSGVDRGYFSLAGLKLTLGSRDFSLHDQHNHRRVAILGDH
VAATSQLKIGDEFKIRGIAFRVIGIMDDESSRFSFGDNQKVFIPSSTFKDIWDTQPNMMLVLPAQGVSSWALREQLRHTF
AQRLHFSPEDQEAVFLPDFGSGVAVITAILRGIQAFLAASGMMTMAVGILGVANMMFLAVTERTREIGVRLAIGATPQRI
QQQFLLEGLLLVVIGALVGLLLAYFGVLLLNHLGLPTWLGEPVITSTTVWLSMLVTSILALAAAYFPARRAAQLEPVIAL
SSRS

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=24.8780487804878, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44656; Mature: 44656

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLQQSWQTLLAHRLKSVLAITAISWGVISVVILMALGEGFYRAQTESFRFLLQETQM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VASGQTSEVWQGMPARRPIQLTESLMREVAQRPEIQRYSIVYENREVSITQQRGTAIGSM
HHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEHHHCHHHHHH
VSGVDRGYFSLAGLKLTLGSRDFSLHDQHNHRRVAILGDHVAATSQLKIGDEFKIRGIAF
HHHHCCCHHEEECEEEEECCCCCCCCCCCCCCEEEEEECCHHCCCEEECCCCEEEEEEEE
RVIGIMDDESSRFSFGDNQKVFIPSSTFKDIWDTQPNMMLVLPAQGVSSWALREQLRHTF
EEEEEECCCCCCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
AQRLHFSPEDQEAVFLPDFGSGVAVITAILRGIQAFLAASGMMTMAVGILGVANMMFLAV
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TERTREIGVRLAIGATPQRIQQQFLLEGLLLVVIGALVGLLLAYFGVLLLNHLGLPTWLG
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
EPVITSTTVWLSMLVTSILALAAAYFPARRAAQLEPVIALSSRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
>Mature Secondary Structure
MRLLLQQSWQTLLAHRLKSVLAITAISWGVISVVILMALGEGFYRAQTESFRFLLQETQM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VASGQTSEVWQGMPARRPIQLTESLMREVAQRPEIQRYSIVYENREVSITQQRGTAIGSM
HHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEHHHCHHHHHH
VSGVDRGYFSLAGLKLTLGSRDFSLHDQHNHRRVAILGDHVAATSQLKIGDEFKIRGIAF
HHHHCCCHHEEECEEEEECCCCCCCCCCCCCCEEEEEECCHHCCCEEECCCCEEEEEEEE
RVIGIMDDESSRFSFGDNQKVFIPSSTFKDIWDTQPNMMLVLPAQGVSSWALREQLRHTF
EEEEEECCCCCCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
AQRLHFSPEDQEAVFLPDFGSGVAVITAILRGIQAFLAASGMMTMAVGILGVANMMFLAV
HHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TERTREIGVRLAIGATPQRIQQQFLLEGLLLVVIGALVGLLLAYFGVLLLNHLGLPTWLG
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
EPVITSTTVWLSMLVTSILALAAAYFPARRAAQLEPVIALSSRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA